Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis, Pulmonary Alveolar Microlithiasis, Primary Ciliary Dyskinesia, Birt-Hogg-Dube Syndrome, Hermansky-Pudlak Syndrome, Hereditary Hemorrhagic Telangiectasia, Non-CF Bronchiectasis, Eosinophilic Lung Diseases, Benign Metastasizing Leiomyomata, and more!

Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease provides a comprehensive, clinically focused textbook on rare and so-called ‘orphan’ pulmonary diseases. The book is oriented towards the diagnostic approach, including manifestations suggesting the disease, diagnostic criteria, methods of diagnostic confirmation, and differential diagnosis, with an overview of management.

This issue of Clinics in Chest Medicine focuses on Sepsis. Articles include: The changing epidemiology and definition of sepsis; risk stratification and prognosis in sepsis: what have we learned from biomarkers and microarrays?;Sepsis outside the ICU: development and implementation of sepsis alert systems; The use of ultrasound in caring for the septic patient; Sepsis resuscitation: Fluid choice and dose; Beyond the golden hours: caring for the septic patient after the initial resuscitation; Vasopressors during sepsis: selection and targets; Dysglycemia and glucose control during sepsis; Cardiac function and dysfunction in sepsis;Goal Directed Resuscitation in Septic Shock; and more!

Dr. Jon Koff has assembled and expert team of authors of the topic of Cystic Fibrosis. Articles include: Epidemiology and Pathobiology, Genetics and genetic medicine in Cystic Fibrosis, Innate and Adaptive Immunity in Cystic Fibrosis, Microbiome in Cystic Fibrosis, Diagnostic Testing in Cystic Fibrosis, Treating Pseudomonas in Cystic Fibrosis, Diagnosis of Adult Patients with Cystic Fibrosis, Transition from Pediatrics to Adult Care, Lung Transplant in Cystic Fibrosis, and more!

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.

This issue of Clinics in Chest Medicine focuses on Advances in Mechanical Ventilation. Articles include: Mechanical Ventilation Design Features; Assessing Respiratory System Mechanical Function; Ventilator Induced Lung Injury; Managing Acute Lung Injury; Patient-Ventilator Interactions; Extracorporeal Gas Exchange; Preventing Ventilator Associated Infections; Ventilator Discontinuation Process; Ventilator Management of the Non-injured Lung; Non-invasive Ventilation; and more!

This book has been replaced by "Rare Diseases of the Respiratory System", ISBN 978-1-84984-167-2 A respiratory physician is only likely to see a few orphan lung diseases each year or even during their career. However, it is essential that specialists are able identify, confirm and diagnosis orphan lung disease in a patient. This Monograph comprehensively covers the most common and/or complex orphan lung diseases. It should be seen as a solid companion to the respiratory specialist each time they need to consider a diagnosis of an orphan disease.

This issue of Clinics in Chest Medicine focuses on Sarciodosis. Drs. Baughman and Culver have put together an expert roster of authors for articles concerning: Etiology of sarcoidosis, Immunology of sarcoidosis, Genetics of Sarcoidosis, Diagnosis of sarcoidosis, Chest imaging, Biomarkers and genetic profiles, Pulmonary Sarcoidosis, Neurosarcoidosis, Cardiac Sarcoidosis, Ocular Sarcoidosis, Quality of life assessments, and more!

This issue of Clinics in Chest Medicine focuses on Pulmonary Complications of Non-Pulmonary Malignancy. Editors Guang-Shing Cheng and Jennifer Possick have assembled an expert team of authors on topics such as: Pulmonary manifestations of non-pulmonary solid malgnancies; Pulmonary manifestations of leukemia and lymphoma; Radiation pneumonitis; Toxicities from conventional chemotherapy; Toxicities from novel targeted therapies; Bacterial pneumonia; Fungal pneumonia; Viral pneumonia; IPS and other early onset non-infectious pulmonary syndromes; Pulmonary GVHD and other late-onset non-infectious pulmonary syndromes; Pulmonary function and pre-transplant risk assessment; Diagnostic Evaluation of Pulmonary Abnormalities in Hematologic Malignancy and HCT; Acute respiratory failure in patients with non-pulmonary malignancy; Critical care prognosis and outcomes in patients with non-pulmonary malignancy; and Palliative and end-of-life care.

This issue of Thoracic Surgery Clinics, guest edited by Dr. Henning A. Gaissert, is devoted to The Chest Wall. Dr. Gaissert has assembled expert authors to review the following topics: Acute Infections of the Chest Wall; Chronic Infections of the Chest Wall; Thoracoplasty for TB in the 21st Century; Chest Wall Trauma: Conservative Management and Surgical Reconstruction; Minimally Invasive Repair of the Pectus Excavatum/Carinatum; Surgical Implications of the Straight Back Syndrome; Management of Primary Soft Tissue Tumors of the Chest Wall; Management of Lung Cancer Invading the Superior Sulcus; Management of Breast Cancer Invading the Chest Wall; Chest Wall Reconstruction without Prosthetic Material; Surgical Management of the Radiated Chest Wall and its Complications; Surgical Management of Primary Tumors of the Osseous Chest Wall; Surgical Management of Lung Cancer Involving the Chest Wall; Prosthetic Reconstruction of the Chest Wall, and more!