In this issue of Otolaryngologic Clinics, guest editors Drs. Devyani Lal, Angela Donaldson, and David Jang bring their considerable expertise to the topic of Unified Airway Disease. Unified airway disease is a recently defined entity that alludes to inflammation disease processes that involve both upper and lower airway, and co-management of these conditions by otolaryngologists and allergy immunologists often result in improved outcomes. In this issue, experts in the field provide a thorough overview of the pathophysiology, diagnosis, and management of unified airway disease through the perspective of an otolaryngologist co-managing the patient with an allergy-immunology colleague. - Contains 16 practice-oriented topics including environmental factors; eosinophilic disease; non-eosinophilic and granulomatous disease; cystic fibrosis; pediatric unified airway disease; unified airway disease medical and surgical management; future directions; and more. - Provides in-depth clinical reviews on unified airway disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Devyani Lal, Angela Donaldson, and David Jang bring their considerable expertise to the topic of Unified Airway Disease. Unified airway disease is a recently defined entity that alludes to inflammation disease processes that involve both upper and lower airway, and co-management of these conditions by otolaryngologists and allergy immunologists often result in improved outcomes. In this issue, experts in the field provide a thorough overview of the pathophysiology, diagnosis, and management of unified airway disease through the perspective of an otolaryngologist co-managing the patient with an allergy-immunology colleague. Contains 16 practice-oriented topics including environmental factors; eosinophilic disease; non-eosinophilic and granulomatous disease; cystic fibrosis; pediatric unified airway disease; unified airway disease medical and surgical management; future directions; and more. Provides in-depth clinical reviews on unified airway disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

A model developed in the past 5 years is that of the "Unified Airway." The concept in this model is that the respiratory mucosa from the middle ear, through the nose and sinuses, down the trachea and through the larynx, and into the bronchioles represents a common epithelium that responds to stimuli in a similar manner. Diseases that affect one portion of this epithelium, therefore, will commonly affect one or more other components. This model has been used to explain the strong overlap and comorbidities among diseases such as allergic rhinitis, chronic rhinosinusitis, and asthma. Since otolaryngologists commonly treat patients with rhinitis, rhinosinusitis, and laryngitis, a full exploration of the overlap among these diseases, as well as the importance of lower respiratory inflammation, is presented in this issue.

This issue of Otolaryngologic Clinics, Guest Edited by Murugappan Ramanathan Jr. and James Whitman Mims, is devoted to Allergy for the Otolaryngologist. Articles in this issue include: New Horizons in the Management of Allergy; The Role of the Sinonasal Epithelium in Allergy; The Role of Allergy in Chronic Rhinosinusitis; Manifestations of Inhalant Allergies Beyond the Nose; The Role of Allergy in Otologic Disease; Asthma Management for the Otolaryngologist; Rational Approach to Allergy Testing (in vitro/in vivo); Advances in Food Allergy; Contemporary Pharmacotherapy of Allergic Inflammation; Clinical Applications of SLIT; Efficacy of SLIT/SCIT; Immunotherapy: Treating with Fewer Allergens?; Management of Anaphylaxis; and Future Horizons in Allergy.

In this issue of Otolaryngologic Clinics, guest editors Drs. Sarah K. Wise and Daniel M. Beswick bring their considerable expertise to the topic of Allergy and Asthma in Otolaryngology. Top experts in the field provide a comprehensive review of up-to-date management strategies for allergic rhinitis and asthma in otolaryngologic settings, including diagnosis, treatment, anticipated future therapies, and associated comorbidities. Contains 15 relevant, practice-oriented topics including the burden of asthma and allergic rhinitis: epidemiology and health care costs; management of asthma for the otolaryngologist: current and future therapies; promising new diagnostic and treatment modalities for allergic rhinitis; update on the role of fungus in allergy, asthma, and the unified airway; air quality, allergic rhinitis, and asthma; allergic rhinitis and its effect on sleep; and more. Provides in-depth clinical reviews on allergy and asthma in otolaryngology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Both acute and chronic cough are responsible for a significant number of ambulatory medical visits annually. The recent comprehensive understanding that “cough is a reflection of underlying disease pays tribute to the multifactorial causes, as well recognition of the respiratory and upper digestive tract as a “physiologic unit. This publication highlights the advances made in managing cough and brings these to otolaryngology practitioners in a concise forum, as well as presenting issues of special interest to laryngologists such as paradoxical vocal fold motion, disordered breathing, irritable larynx, evolution of the vagus as a protective circuit, the importance of cough in deglutition, and surgical interventions. Some of the topics include: The cough reflex, sensory receptors, and neurogenic mediators; Mucus and mucins; Cough and Swallowing dysfunction; Cough due to asthma, cough-variant asthma, and nonasthmatic eosinophilic bronchitis; Occupational, environmental, and irritant induced cough; Pharmacologic management; Unexplained cough; Cough in the pediatric population; and Rhinogenic laryngitis, cough and the unified airway; among others.

In this issue of Otolaryngologic Clinics, guest editors Drs. Karen M. Kost and Gina D. Jefferson bring their considerable expertise to the topic of Larynx Cancer. Top experts in the field cover key topics such as perioperative assessment/prehabilitation; dysplastic lesions of the larynx; radiation for early glottic cancer; surgical management of supraglottic cancer; salvage surgery; vocal rehabilitation and quality of life; swallowing function after treatment of laryngeal cancer; end-of-life care; and more. Contains 18 relevant, practice-oriented topics including diagnostic assessment (imaging) and staging of laryngeal cancer; surgical treatment of early glottic cancer; surgical management of advanced glottic cancer; the role of robotic surgery in laryngeal cancer; reconstruction options; and more. Provides in-depth clinical reviews on larynx cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Erika Woodson and Matthew Carlson bring their considerable expertise to the topic of Vestibular Schwannoma. Top experts in the field cover key topics such as evidenced-based management and new conceptual framework for wait-and-scan management of vestibular schwannoma; optimizing facial nerve outcomes during microsurgery; management of NF2-associated vestibular schwannomas; medical therapy for vestibular schwannoma; salvage management of vestibular schwannoma; and more. - Contains 19 relevant, practice-oriented topics including guiding patients through decision making in sporadic vestibular management; intraoperative cochlear nerve monitoring in sporadic vestibular schwannoma; stereotactic radiosurgery for sporadic vestibular schwannoma; management of complications in vestibular schwannoma surgery; quality of life outcomes for sporadic vestibular schwannoma; and more. - Provides in-depth clinical reviews on vestibular schwannoma, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Romaine F. Johnson and Elton M. Lambert bring their considerable expertise to the topic of Pediatric Otolaryngology. Top experts in the field cover key topics such as single-sided deafness, eustachian tube dysfunction, drug-induced sleep endoscopy; drooling and aspiration; pediatric tracheostomy teams; 3-D printing in otolaryngology; and more. Contains 15 relevant, practice-oriented topics including enhanced recovery after surgery; aerodigestive approaches to chronic cough; slide tracheoplasty: tracheal rings and beyond; COVID-19 and pediatric otolaryngology; and more. Provides in-depth clinical reviews on pediatric otolaryngology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.