This issue of Otolaryngologic Clinics, Guest Edited by Murugappan Ramanathan Jr. and James Whitman Mims, is devoted to Allergy for the Otolaryngologist. Articles in this issue include: New Horizons in the Management of Allergy; The Role of the Sinonasal Epithelium in Allergy; The Role of Allergy in Chronic Rhinosinusitis; Manifestations of Inhalant Allergies Beyond the Nose; The Role of Allergy in Otologic Disease; Asthma Management for the Otolaryngologist; Rational Approach to Allergy Testing (in vitro/in vivo); Advances in Food Allergy; Contemporary Pharmacotherapy of Allergic Inflammation; Clinical Applications of SLIT; Efficacy of SLIT/SCIT; Immunotherapy: Treating with Fewer Allergens?; Management of Anaphylaxis; and Future Horizons in Allergy.

This issue of Otolaryngologic Clinics, guest edited by Drs. Sarah K. Wise, Ashkan Monfared, and Nicole C. Schmitt is devoted to Biologics in Otolaryngology. This issue is one of six selected each year by our series consulting editor, Dr. Sujana S. Chandrasekhar. Articles in this issue include: Biologics in otolaryngology overview, Current evidence for biologic therapy in chronic rhinosinusitis with nasal polyposis, Choosing the right patient for biologic therapy in CRSwNP, Knowledge gaps and research needs for biologic therapy in rhinology practice, Mechanisms and practical use of biologic therapies for allergy and asthma indications, Immunotherapeutic strategies in head and neck cancer, Cetuximab in head and neck cancer, Anti-PD-1 immune checkpoint blockade for head and neck cancer, Advances in adoptive cell therapy for head and neck cancer, Biologics for the treatment of recurrent respiratory papillomatosis, Past and future biologics for otologic disorders, Biological treatments for Neurofibromatosis Type II and other skullbase disorders, and Biologics in treatment of autoimmune ear disorders.

In this issue of Otolaryngologic Clinics, guest editors Drs. Anais Rameau and Matthew G. Crowson bring their considerable expertise to the topic of Artificial Intelligence in Otolaryngology. Top experts in the field cover timely topics in the areas of Best Practices, AI Modalities, Implementation and Governance, and Subspecialty AI. - Contains 17 relevant, practice-oriented topics including clinical data/machine learning; generative AI and otolaryngology-head and neck surgery; ethics; AI in otology and neurotology; AI in facial plastic and reconstructive surgery; AI in pediatric otolaryngology; and more. - Provides in-depth clinical reviews on artificial intelligence in otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Michael D. Seidman and Marilene B. Wang bring their considerable expertise to the topic of Complementary and Integrative Medicine and Nutrition in Otolaryngology. Many patients use heath care approaches that are not part of conventional medical care or that may have origins outside of usual Western practice, while also using conventional health care. In this issue, top experts summarize the current knowledge of complementary and integrative medicine and nutrition as they relate to the care of patients in otolaryngology practices, providing a comprehensive resource that physicians and allied health providers can rely on for accurate patient counseling. - Contains 19 practice-oriented topics including diet and health; why otolaryngologists should be interested in psychedelic medicine; probiotics for otolaryngology disorders; sinus issues and natural alternatives; CIM and prevention of hearing loss; CIM and the voice; natural alternatives and the common cold/flu; otitis media; and more. - Provides in-depth clinical reviews on complementary and integrative medicine and nutrition in otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Romaine F. Johnson and Elton M. Lambert bring their considerable expertise to the topic of Pediatric Otolaryngology. Top experts in the field cover key topics such as single-sided deafness, eustachian tube dysfunction, drug-induced sleep endoscopy; drooling and aspiration; pediatric tracheostomy teams; 3-D printing in otolaryngology; and more. - Contains 15 relevant, practice-oriented topics including enhanced recovery after surgery; aerodigestive approaches to chronic cough; slide tracheoplasty: tracheal rings and beyond; COVID-19 and pediatric otolaryngology; and more. - Provides in-depth clinical reviews on pediatric otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Joni K. Doherty and Michael Setzen bring their considerable expertise to the topic of Comprehensive Management of Headache for the Otolaryngologist. As many types of headache tend to masquerade as sinus headache, an understanding of the peripheral mechanisms of specific headache types is essential for otolaryngologists to effectively diagnose and treat patients, according to a study published in the American Journal of Otolaryngology. In this issue, top experts in the field address key issues such as novel devices for sinus headache, headache diagnosis in children and adolescents, headache and pregnancy, side-locked and nummular headaches, and much more. - Contains 14 relevant, practice-oriented topics including the role of the otolaryngologist in the evaluation and management of headache; "Sinus headache: rhinogenic headache, nonrhinogenic headache, or migraine; idiopathic intracranial hypertension; neuralgia and atypical facial, ear, and head pain; and more. - Provides in-depth clinical reviews on comprehensive management of headache, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Jayne Stevens and Kiran Kakarala bring their considerable expertise to the topic of Reconstruction Options in Otolaryngology. Top experts in the field cover major salient topics regarding reconstruction in otolaryngology—from management of trauma and facial nerve reconstruction to free flap options and optimizing functional outcomes in oncologic resections—making this issue an up-to-date, one-stop reference for surgeons involved in head and neck reconstruction. - Contains 19 practice-oriented topics including oral cavity reconstruction; lateral skull base and auricular reconstruction; reconstruction after skin cancer resection; management of facial trauma; virtual surgical planning in head and neck reconstruction; prosthetics in head and neck reconstruction; and more. - Provides in-depth clinical reviews of reconstruction options in otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Regina Rodman and C. Michael Haben bring their considerable expertise to the topic of Gender Affirmation Surgery in Otolaryngology. Top experts in the field cover key topics such as masculinization laryngoplasty; facial analysis, browlift and brow position; genioplasty for chin reduction; Adam's apple reduction; cheek augmentation; voice tuning refinements with laser; and more. - Contains 17 relevant, practice-oriented topics including approach to the transgender patient; impact and expectations of hormone replacement therapy or orchiectomy on the timing of, or necessity for, gender affirmation voice surgery; the role of voice as a source of dysphoria and gender identity; feminization laryngoplasty; voice and speech training for the transgender patient: what the otolaryngologist should know; and more. - Provides in-depth clinical reviews on gender affirmation surgery in otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Otolaryngologic Clinics, guest editors Drs. Karen M. Kost and Gina D. Jefferson bring their considerable expertise to the topic of Larynx Cancer. Top experts in the field cover key topics such as perioperative assessment/prehabilitation; dysplastic lesions of the larynx; radiation for early glottic cancer; surgical management of supraglottic cancer; salvage surgery; vocal rehabilitation and quality of life; swallowing function after treatment of laryngeal cancer; end-of-life care; and more. - Contains 18 relevant, practice-oriented topics including diagnostic assessment (imaging) and staging of laryngeal cancer; surgical treatment of early glottic cancer; surgical management of advanced glottic cancer; the role of robotic surgery in laryngeal cancer; reconstruction options; and more. - Provides in-depth clinical reviews on larynx cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Otolaryngologic Clinics, Guest Edited by Drs. Anna A. Pashkova, Peter F. Svider, and Jean Anderson Eloy, is devoted to Pain Management for the Otolaryngologist. This issue is one of six selected each year by our series Consulting Editor, Sujana S. Chandrasekhar. Articles in this important issue include: Overview of Pain Management for the Otolaryngologist; Pre-Operative Optimization; Local Blocks and Regional Anesthesia in the Head and Neck; Acute Pain Management following Head and Neck Surgery; Acute Pain Management following Sleep Surgery; Perioperative Analgesia for Thyroid and Parathyroid Surgery; Perioperative Analgesia for Sinus Surgery; Perioperative Analgesia following Otologic Surgery; Acute Pain Management following Facial Plastic Surgery; Perioperative Analgesia for Pediatric Patients Undergoing Otolaryngologic Procedures; Non-Opioid Adjuncts and Alternatives; Postoperative Analgesia in the Chronic Pain Patient; Non-Enteral Pain Management; Chronic Pain Management in the Head and Neck Patient; Controlled Substance Agreements; Pain Psychology; Sinus Headache; and Quality Improvement in Pain Medicine.