In this issue of Critical Care Clinics, guest editors Drs. Robert M. Kliegman and Brett J. Bordini bring their considerable expertise to the topic of Undiagnosed and Rare Diseases in Critical Care. Top experts in the field cover key topics such as critical genetic arrhythmia disorders, uncommon causes of rhabdomyolysis, status epilepsy syndromes, autoimmune encephalitis, rapid-onset paralysis and weakness, and more. - Contains 17 relevant, practice-oriented topics including understanding cognitive diagnostic errors in the ICU; rapid WES/WGS in the ICU; diagnostic time-outs to improve diagnosis; when "sepsis is not sepsis: MAS, HLH, malignancies and other sepsis mimics; all that wheezes is not asthma or bronchiolitis; and more. - Provides in-depth clinical reviews on undiagnosed and rare diseases in critical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Critical Care Clinics, guest editors Drs. Lori Shutter and Deepa Malaiyandi bring their considerable expertise to the topic of Neurocritical Care, a rapidly growing specialty of complex care. Top experts in the field provide up-to-date articles on important clinical trials and evidence-based care of the critically ill patient with neurological injury. - Contains 16 practice-oriented topics including current management of acute ischemic stroke; status epilepticus: a neurological emergency; neurotrauma and ICP management; neuropharmacology in the ICU; artificial intelligence and big data science in neurocritical care; and more. - Provides in-depth clinical reviews on neurocritical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Critical Care Clinics, guest editors Drs. Michelle Ng Gong and Gregory S. Martin bring their considerable expertise to the topic of COVID-19. Top experts in the field cover key topics such as ECMO in COVID-19, neurologic manifestations and sequelae in COVID-19, pediatric COVID-19, anti-viral and anti-inflammatory therapeutics in COVID-19, the critical care surge during COVID-19 and lessons for the future, and more. - Contains 11 relevant, practice-oriented topics including post-acute sequelae of SARS CoV-2 infection; COVID-19 and renal failure; the role of acute thrombosis in COVID-19; COVID ARDS: different phenotype of ARDS or same diversity of phenotype in ARDS; COVID-19 in the critically ill pregnant patient; and more. - Provides in-depth clinical reviews on COVID-19, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics, guest edited by Dr. Janice L. Zimmerman, focuses on Toxicology. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Pharmacokinetic and pharmacodynamic principles for toxicology, Use of extracorporeal techniques in poisonings, Drugs of Abuse, Cardiovascular Drug Toxicity, Anticoagulant and Anti-platelet Drug Toxicity and Psychotropic Agents.

This issue of Critical Care Clinics, guest edited by Drs. Michael Matthay and Kathleen Dori Lui, focuses on Acute Respiratory Distress Syndrome. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Epidemiology, Environmental Factors, Clinical Diagnosis, Physiology of ARDS, including COVID-19, Pathogenesis Based on Clinical Studies, Genetics of ARDS, Ventilator Management and Rescue Therapy with ECMO, Acute Kidney Injury and ARDS, Pharmacologic Therapies and ARDS and Long Term Outcomes from ARDS. - Provides in-depth, clinical reviews on ARDS, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Critical Care Clinics, guest editors Drs. Robert M. Kliegman and Brett J. Bordini bring their considerable expertise to the topic of Undiagnosed and Rare Diseases in Critical Care. Top experts in the field cover key topics such as critical genetic arrhythmia disorders, uncommon causes of rhabdomyolysis, status epilepsy syndromes, autoimmune encephalitis, rapid-onset paralysis and weakness, and more. Contains 17 relevant, practice-oriented topics including understanding cognitive diagnostic errors in the ICU; rapid WES/WGS in the ICU; diagnostic time-outs to improve diagnosis; when "sepsis" is not sepsis: MAS, HLH, malignancies and other sepsis mimics; all that wheezes is not asthma or bronchiolitis; and more. Provides in-depth clinical reviews on undiagnosed and rare diseases in critical care, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Critical Care Clinics, guest editor Paul Bergl brings his considerable expertise to the topic of Diagnostic Excellence in the ICU. - Provides in-depth, clinical reviews on the latest updates in Diagnostic Excellence in the ICU, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Medical Clinics of North America, guest editors Drs. Heather Toth, Robert Kliegman, and Brett Bordini brings their considerable expertise to the topic of Adolescent Undiagnosed and Rare Diseases. Top experts address diagnostic dilemmas, disease mimics, unusual manifestations of common diseases, and rare disorders presenting as more common diseases in adolescents. - Contains 15 relevant, practice-oriented topics including syndromes with severe acne; common variable immunodeficiency (CVID); overlapping pain syndrome; late onset congenital hypoventilation syndrome (LOCH); adolescent onset of muscle weakness; and more. - Provides in-depth clinical reviews on adolescent undiagnosed and rare diseases, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Critical Care Nursing Clinics, guest editor and clinical nurse specialist Cynthia Benz brings her considerable expertise to the topic of Care for the Liver Failure Patient. Nurse involvement in chronic and fatal liver diseases requires interventions to improve symptom control, reduce inpatient care, prevent worsening of condition, and improve quality of life. In this issue, top experts focus on these nursing interventions for patients experiencing liver failure or the eventuality of liver failure. - Contains 11 practice-oriented topics including acute liver failure in the pediatric patient; right sided heart failure and liver failure; hepatocellular carcinoma; ascites; esophageal varices; and more. - Provides in-depth clinical reviews on care for the liver failure patient, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.