In this issue of Critical Care Clinics, guest editor Paul Bergl brings his considerable expertise to the topic of Diagnostic Excellence in the ICU. Provides in-depth, clinical reviews on the latest updates in Diagnostic Excellence in the ICU, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Critical Care Clinics, guest editor Paul Bergl brings his considerable expertise to the topic of Diagnostic Excellence in the ICU. Provides in-depth, clinical reviews on the latest updates in Diagnostic Excellence in the ICU, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Critical Care Clinics, guest edited by Dr. Janice L. Zimmerman, focuses on Toxicology. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Pharmacokinetic and pharmacodynamic principles for toxicology, Use of extracorporeal techniques in poisonings, Drugs of Abuse, Cardiovascular Drug Toxicity, Anticoagulant and Anti-platelet Drug Toxicity and Psychotropic Agents.

In this issue of Critical Care Clinics, guest editors Drs. Michelle Ng Gong and Gregory S. Martin bring their considerable expertise to the topic of COVID-19. Top experts in the field cover key topics such as ECMO in COVID-19, neurologic manifestations and sequelae in COVID-19, pediatric COVID-19, anti-viral and anti-inflammatory therapeutics in COVID-19, the critical care surge during COVID-19 and lessons for the future, and more. - Contains 11 relevant, practice-oriented topics including post-acute sequelae of SARS CoV-2 infection; COVID-19 and renal failure; the role of acute thrombosis in COVID-19; COVID ARDS: different phenotype of ARDS or same diversity of phenotype in ARDS; COVID-19 in the critically ill pregnant patient; and more. - Provides in-depth clinical reviews on COVID-19, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics, guest edited by Drs. Michael Matthay and Kathleen Dori Lui, focuses on Acute Respiratory Distress Syndrome. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Epidemiology, Environmental Factors, Clinical Diagnosis, Physiology of ARDS, including COVID-19, Pathogenesis Based on Clinical Studies, Genetics of ARDS, Ventilator Management and Rescue Therapy with ECMO, Acute Kidney Injury and ARDS, Pharmacologic Therapies and ARDS and Long Term Outcomes from ARDS. - Provides in-depth, clinical reviews on ARDS, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Critical Care Clinics, guest editors Drs. Robert M. Kliegman and Brett J. Bordini bring their considerable expertise to the topic of Undiagnosed and Rare Diseases in Critical Care. Top experts in the field cover key topics such as critical genetic arrhythmia disorders, uncommon causes of rhabdomyolysis, status epilepsy syndromes, autoimmune encephalitis, rapid-onset paralysis and weakness, and more. - Contains 17 relevant, practice-oriented topics including understanding cognitive diagnostic errors in the ICU; rapid WES/WGS in the ICU; diagnostic time-outs to improve diagnosis; when "sepsis is not sepsis: MAS, HLH, malignancies and other sepsis mimics; all that wheezes is not asthma or bronchiolitis; and more. - Provides in-depth clinical reviews on undiagnosed and rare diseases in critical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics edited by Dr. Robert Hyzy on Enhancing the Quality of Care in the ICU features topics such as: Taking Central Line-Associated Bloodstream Infection Rates to Zero, Preventing ICU Delirium, Avoiding Clostridium difficile associated diarrhea, Reducing ventilator associated complications and pneumonia, Can Venous Thromboembolism be avoided?, Preventing urinary catheter associated infections, Improving ICU quality through collaboratives, Do performance measures enhance patient quality in the ICU, and The Future of Quality in the ICU.

In this issue of Critical Care Clinics, guest editors Drs. Rishikesan Kamaleswaran and Andre L. Holder bring their considerable expertise to the topic of Data Science in Critical Care. Data science, the field of study dedicated to the principled extraction of knowledge from complex data, is particularly relevant in the critical care setting. In this issue, top experts in the field cover key topics such as refining our understanding and classification of critical illness using biomarker-based phenotyping; predictive modeling using AI/ML on EHR data; classification and prediction using waveform-based data; creating trustworthy and fair AI systems; and more. - Contains 15 relevant, practice-oriented topics including AI and the imaging revolution; designing "living, breathing clinical trials: lessons learned from the COVID-19 pandemic; the patient or the population: knowing the limitations of our data to make smart clinical decisions; weighing the cost vs. benefit of AI in healthcare; and more. - Provides in-depth clinical reviews on data science in critical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Evidence-Based Practice of Critical Care, 2nd Edition, presents objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly 200 critical-care experts, this highly regarded title remains the only book of its kind that provides a comprehensive framework for translating evidence into practice, making it a valuable resource for both residents and practitioners. Tap into the expertise of nearly 200 critical-care experts who discuss the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines. Find the information you need quickly with tables that summarize the available literature and recommended clinical approaches. Navigate a full range of challenges from routine care to complicated and special situations. Stay up to date with new issues and controversies such as the redefinition of sepsis • changing approaches to fluid administration • immune suppression in sepsis • monitoring the microcirculation • the long-term sequelae of critical illness • minimizing ventilator associated lung injury • the benefits of evidence-based medicine management guidelines • rapid response teams • and more. Benefit from all-new sections covering persistent critical illness and the role of advanced practice nurses and physician assistants in the ICU.