It gives us great pleasure to contribute a short introduction outstanding book. This comprehensive work provides an to this important volume. immense fund of information, and will be an invaluable The transplantation of thoracic organs - heart,heart source of knowledge to physicians, surgeons, and scientists lung, lung - is a field of surgery that is expanding annually. for many years to come. The use of mechanical assist devices and artificial hearts to support patients awaiting transplantation is also developing rapidly, and further advances in this field may eventually April 1990 Christiaan Barnard lead to a totally implantable device that will function Cape Town, South Africa successfully for many years. It is therefore timely that such a volume as this should be made available to those who wish to be brought up-to date with the current state of knowledge in these related fields. The editors have done us all a great service in bringing together experts in every aspect of heart and Nazih Zuhdi lung transplantation and replacement to contribute to this Oklahoma City, USA Xl Preface The fields of the transplantation and replacement of thoracic Refinements in bioengineering have enabled mechanical organs have expanded immensely since the first human assist devices and the total artificial heart to support patients to-human heart transplant was performed in 1967. This successfully until a suitable donor becomes available.

A comprehensive text from the leading transplant centres on the medical management of thoracic organ transplantation, covering the assessment of patients for possible transplantation, through to managing patients after transplantation including any possible complications and shared care aspects of long term management

This book presents a clear and concise summary of the clinical tenets of lung transplantation with an update on recent developments in the field. It examines the operational principles which underpin successful lung transplantation and shows how an evidenced based approach combined with wisdom borne of experience leads to better outcomes in day-to-day management. Focused on simplicity and elegance of style with ample visual images, this book provides a unique overview of trends and strategies for the best outcomes in lung transplantation. Approachable and easily digested, this book will be a go-to resource for professionals seeking a succinct and well-illustrated guide to this growing area of surgical transplantation.

An excellent resource for practitioners who participate in the care of transplant patients, this comprehensive new second edition covers all aspects of heart and lung transplantation. Each area of the field is fully addressed, with documentation and practical points for patient management provided throughout. An especially notable feature of this new edition is the greatly expanded coverage of lung transplantation, with every chapter rewritten to reflect changes to current information in the field. Complete coverage of all aspects of heart and lung transplantation, including evaluation and management of transplant patients, anesthetic and operative techniques, postoperative care, biopsy techniques, immunosuppressive management, long-term management, and pediatric transplantation. Thorough discussions of programmatic issues, donor evaluation and graft preservation, morbidity associated with transplantation, and future implications. Contributions from renowned experts, many from Johns Hopkins University and Stanford University. Includes two new editors: Edward Kasper, MD and James Theodore, MD. Offers significantly expanded coverage on lung transplantation, sections on single lung transplantation, current rejection management, new operative techniques, and effective patient care. Presents several new chapters including: Medical and Surgical Alternatives to Cardiac Transplantation (Ch. 8), Living Related Lung Transplantation (Ch. 43), Lung Pathology (Ch. 28), Immunosuppressive Therapy in the 21st Century (Ch. 48), and Management of Congestive Heart Failure in the 21st Century (Ch. 49). Covers new information on quality of care, circulatory support and Mechanical Circulatory Assistance Prior to Heart Transplantation (Ch. 12).

We are truly in an era of change not only in terms of technology but in the type of patient we are caring for. That is why I feel this book is exciting in that it presents the team approach to the transplant patient. I am confident that the pioneers of cardiac transplantation would be pleased with our response to challenges in healthcare today and be pleased with the final product.

The first book of its kind, this reference describes current diagnostic and treatment strategies for acute and chronic heart failure in the fetus, neonate, child, and young adult-encompassing every aspect of pediatric heart failure including historical perspectives, the latest technologies in mechanical circulatory support, and recent information on the psychosocial aspects of heart failure in children.

Introductory Chapter: Dedicated Initial Giants Breaking the Barriers to Successful Cardiac Transplantation Therapy.

Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease Comprehensive textbook covering all aspects of the care of patients with advanced heart or lung disease Transplantation and Mechanical Support for End-Stage Heart and Lung Disease is the most comprehensive and contemporary textbook available that addresses the medical and surgical treatment options for patients with end-stage heart and lung disease. All facets of these complex and resource-intensive therapies are covered by leading experts — including the basics of transplant immunology, databases, regulatory and ethical aspects of transplantation and conventional and new modalities of donor organ harvest. Transplantation and Mechanical Support for End-Stage Heart and Lung Disease includes further information on topics such as: Historical developments that facilitated heart and lung transplantation; engineering advances in continuous flow technologies Transplant organizations, oversight, structure, process, databases and registries in the thoracic transplants and MCS field Current strategies in immune modulation, desensitization protocols and mechanisms of allograft rejection and tolerance/immunosenescence Detailed descriptions of donor and recipient surgical procedures as well as comprehensive implantation techniques for all available short- and long-term mechanical circulatory support devices, including ECMO Organ allocation and prioritization, donor evaluation, high risk donors, marginal donors, and risk assessment Richly enhanced with summary tables and color illustrations to provide an engaging and supportive learning experience, the book will serve as a highly valuable source of contemporary knowledge for medical students, residents, nurses, perfusionists, physicians and surgeons involved in the care of these desperately ill group of patients. “This comprehensive book covers all aspects of advanced heart and lung failure treatment, including shock, short-term and durable mechanical assistance, as well as transplantation. The in-depth information will be welcome by newcomers in the field as well as seasoned veterans.” —Andreas Zuckermann, M.D Vice-Chair, Department of Cardiac Surgery, Director of Cardiac Transplantation Program, Medical University of Vienna, Vienna General Hospital “This comprehensive tour-de-force compendium covers practical issues of clinical administration, program development, care pathways, ongoing challenges and opportunities in each treatment area as a must go-to reference for guidance in the rapidly evolving fields of mechanical circulatory support and transplantation.” —Mandeep R. Mehra, MBBS, MSc, FRCP Executive Director, Center for Advanced Heart Disease, Brigham and Women’s Hospital, Harvard Medical School “This unique textbook authored by key opinion leaders is a refreshing ???wind of change??? in our field, one that will well serve all professionals involved in the care of end-stage heart and lung patients for many years to come.” —Marcelo Cypel MD, MSc, FACS, FRCSC Surgical Director Ajmera Transplant Centre at UHN , University of Toronto

Experimental Lung Transplantation: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Experimental Lung Transplantation in a concise format. The editors have built Experimental Lung Transplantation: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Experimental Lung Transplantation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Experimental Lung Transplantation: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.