An excellent resource for practitioners who participate in the care of transplant patients, this comprehensive new second edition covers all aspects of heart and lung transplantation. Each area of the field is fully addressed, with documentation and practical points for patient management provided throughout. An especially notable feature of this new edition is the greatly expanded coverage of lung transplantation, with every chapter rewritten to reflect changes to current information in the field. Complete coverage of all aspects of heart and lung transplantation, including evaluation and management of transplant patients, anesthetic and operative techniques, postoperative care, biopsy techniques, immunosuppressive management, long-term management, and pediatric transplantation. Thorough discussions of programmatic issues, donor evaluation and graft preservation, morbidity associated with transplantation, and future implications. Contributions from renowned experts, many from Johns Hopkins University and Stanford University. Includes two new editors: Edward Kasper, MD and James Theodore, MD. Offers significantly expanded coverage on lung transplantation, sections on single lung transplantation, current rejection management, new operative techniques, and effective patient care. Presents several new chapters including: Medical and Surgical Alternatives to Cardiac Transplantation (Ch. 8), Living Related Lung Transplantation (Ch. 43), Lung Pathology (Ch. 28), Immunosuppressive Therapy in the 21st Century (Ch. 48), and Management of Congestive Heart Failure in the 21st Century (Ch. 49). Covers new information on quality of care, circulatory support and Mechanical Circulatory Assistance Prior to Heart Transplantation (Ch. 12).

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​

Lung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, the book is divided into four broad sections: General Topics, Donor Management, Recipient Management and Outcome, and the Future o

Lung transplantation is a successful therapeutic option for patients with end-stage respiratory failure. Although the clinical outcomes of this procedure have been constantly improving, yet the care of patients undergoing lung transplantation is still a striking challenge for the entire team involved in the process. The complexity of a clinical lung transplant program requires a trained, multi-specialist team and a continuing technical update. Technology provides exciting new opportunities for the improvement of clinical outcomes. This text provides a comprehensive, practical and up-to-date insight into clinical lung transplantation. It moves along the pre-, intra-, and post-operative phases of transplantation. It explores the most relevant surgical, medical and immunological concepts of this field. The contents focusses not only on the technical, scientific and medical aspects of lung transplantation, but also on the administrative, regulatory and nursing topics of running a lung transplant program. Rather than presenting purely theoretical chapters, the text sets the focus on clinical dilemmas and practical issues involving all the professionals who actively run a lung transplant program. The reader will be able to access the book for reference on any topic related to clinical care in lung transplantation. This text is intended as a practical resource for surgeons, physicians and health professionals involved in lung transplantation or in setting up a lung transplant program. All chapters are written by experts in their fields and will include the most up to date scientific and clinical information. The overall intent of this publication is to assist the health care provider in all the daily aspects of lung transplantation and to offer a modern, practical source of suggestions and answers.

The first book of its kind, this reference describes current diagnostic and treatment strategies for acute and chronic heart failure in the fetus, neonate, child, and young adult-encompassing every aspect of pediatric heart failure including historical perspectives, the latest technologies in mechanical circulatory support, and recent information on the psychosocial aspects of heart failure in children.

This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.

Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy. This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.

This truly comprehensive reference is devoted to every aspect of heart transplantation. It not only covers the surgical procedures for the donor and recipient, but also explores pre and post operative patient management, operative techniques and non-surgical cardiac management options. The 3 reasons you need this book are: (1) Extensive outline and bolded phrases will provide you with QUICK and EASY access to the information; (2) Over 700 illustrations will provide an additional visual aid to enhance your understanding of the text; and (3) Access to information on all the most currently used immunosuppressive drugs and other modalities with helpful tables

The Lung Transplantation Handbook (Second Edition), originally published under the title Things You Should Know About Lung Transplantation: Before, During and After has now been updated and expanded in this, the second edition.

Pediatric Heart Transplantation