Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. - Covers the depth and breadth of this interdisciplinary area of research - Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering - Contains contributions from leading experts in the field that are heavily illustrated

With contributions by numerous experts

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.

Biofliudics has gained in importance in recent years, forcing engineers to redefine mechanical engineering theories and apply them to biological functions. To date, no book has successfully done this. Biofliud Mechanics in Cardiovascular Systems is one of the first books to take an interdisciplinary approach to the subject. Written by a professor and researcher, this book will combine engineering principles with human biology to deliver a text specifically designed for biomedical engineering professionals and students.

New Frontiers in Biomedical Engineering will be an edited work taken from the 1st Annual World Congress of Chinese Biomedical Engineers - Taipei, Taiwan 2002. As the economy develops rapidly in China and the Asian-Pacific population merges into the global healthcare system, many researchers in the West are trying to make contact with the Chinese BME scientists. At WCCBME 2002, invited leaders, materials scientists, bioengineers, molecular and cellular biologists, orthopaedic surgeons, and manufacturers from P.R. of China, Taiwan, Singapore and Hong Kong covered all five major BME domains: biomechanics, biomaterials and tissue engineering, medical imaging, biophotonics and instrumentation, and rehabilitation. This edited work taken from the World Congress proceedings will capture worldwide readership.

This text describes and illustrates with some 700 detailed anatomic and surgical drawings the whole spectrum of surgical procedures employed to treat acquired and congenital diseases of the heart and great vessels in adults and children. A rather traditional chapter on history of cardiac surgery precedes chapters dedicated to quality improvement, followed by ICU management in adult and pediatric cardiac surgery, and techniques of extracorporeal circulation in both age groups. Further special topics are cardiovascular tissue engineering, minimally invasive cardiac surgery, endovascular treatment of aortic diseases, and cardiac assist devices, including total artificial heart. Written by 71 internationally recognized experts from 40 cardiac units in Central Europe and North America, this book will be invaluable not only for both novice and experienced surgeons, but also for all physicians, nurses, and technicians caring for patients with heart disease of any type, at any age.

A practical manual to aid the management of women with heart disease who are pregnant or who are considering pregnancy, Heart Disease in Pregnancy also provides an introduction to the physiological changes of pregnancy and the relevant obstetric knowledge and processes needed for a cardiologist to successfully manage a pregnant woman.