There is an ever-increasing emphasis on evidence-based medicine that is distinguished by systematic crafting of the patient-centered research question, detailed literature searches, and careful appraisal of the resulting evidence. The consensus that ultimately emerges must then be applied in specific clinical settings, and it is to this process that translational effectiveness analysis refers. This portable and easy-to-use handbook is intended as a practical teaching guide on translational effectiveness for students and clinicians. Specifically, it will serve as a primer on patient-centered outcomes research methodology in the health sciences and explain how to acquire and understand the fundamental data that determine which reports are valued as the “best available” evidence. It presents an accessible and readily intelligible set of principles which doctors, dentists, nurses, and insurance carriers will be able to use in the process of health care-related decision-making. ​

Practical Biostatistics: A Step-by-Step Approach for Evidence-Based Medicine, Second Edition presents a complete resource of biostatistical knowledge meant for health sciences students, researchers and health care professionals. The book's content covers the investigator's hypothesis, collective health, observational studies, the biostatistics of intervention studies, clinical trials and additional concepts. Chapters are written in a didactic way, making them easier to comprehend by readers with little or no background on statistics. Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision-making using statistical analyses of scientific methods and outcomes to drive further experimentation and diagnosis. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or hands-on guide on how to effectively incorporate biostatistics in clinical trials and research projects. - Explains biostatistics in a didactic way for students, researchers and professionals of health sciences with little or no background on mathematics - Presents a new section dedicated to epidemiology and public health, broadening content from the previous edition - Written by medical doctors with vast experience on biostatistics and teaching who develop the content based on real cases for better applicability by readers

*Customized presentation for biological investigators with examples taken from current clinical trials in multiple disciplines.

This book addresses the challenge of presenting biostatistics to medical and health science audiences coherently. Tailored for students and researchers, its 13 chapters progress logically from foundational concepts like measurement scales and statistical calculations to advanced topics such as probability, correlation, regression and Health and disease measures. Practical examples enhance relevance, and its gradual approach ensures easy comprehension even for non-statisticians. The book's practical emphasis shines as it culminates in teaching the use of SPSS software for result interpretation, bridging theory and practice effectively. It empowers medical professionals to confidently understand and apply statistical concepts in their work, serving as an indispensable resource in navigating the intricacies of biostatistics in medical and health sciences.

This book is designed to enable dentists to understand various aspects of dental sleep medicine, and to recognize the signs and symptoms of sleep disorders in their patients. It discusses potential negative impact of a sleep disorder on oral and systemic health, and shows how to collaborate with others in order to implement appropriate patient management. The first part of the book concentrated on the scientific background of sleep medicine in connection to dentistry covering the physiology of sleep, classifications of sleep disorders, their diagnosis as well as medical and dental comorbidities. The second part of the book is dedicated to clinical applications like CPAP therapy, oral appliance therapy, surgical procedures and adjunct therapies. Last, the future of dental sleep medicine is discussed. Each chapter is written by specialized researchers and clinicians in the field making the book a useful guide for dental clinicians all around the world.

All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the _x001F_field of bioinformatics, as well as some future directions. Each chapter is didactically organized and includes introduction, applications, tools, and future directions to cover the topics thoroughly. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high-throughput technologies, drug informatics, system and network biology, and machine learning. It is a valuable resource for researchers and graduate students who are interested to learn more about bioinformatics to apply in their research work. - Presents a holistic learning experience, beginning with an introduction to bioinformatics to recent advancements in the field - Discusses bioinformatics as a practice rather than in theory focusing on more application-oriented topics as high-throughput technologies, system and network biology, and workflow management systems - Encompasses chapters on statistics and machine learning to assist readers in deciphering trends and patterns in biological data

Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.

Essentials of Biostatistics in Public Health, Fourth Edition provides a fundamental and engaging background for students learning to apply and appropriately interpret biostatistics applications in the field of public health. Many examples are drawn directly from the author's remarkable clinical experiences with the renowned Framingham Heart Study, making this text practical, interesting, and accessible for those with little mathematical background. The examples are real, relevant, and manageable in size so that students can easily focus on applications rather than become overwhelmed by computations. The Fourth Edition has been thoroughly updated, and now offers a new chapter on career opportunities in biostatistics and new case studies focused on COVID-19 within each chapter. This edition also includes free access to JMP® Student Subscription (a $29.95 value). New cases based on COVID-19 highlight the importance and practical applications of biostatistics for addressing the pandemic.

"Biostatistics in Clinical Trials" gehört zur Reihe 'Wiley Reference Series in Biostatistics' und basiert auf der renommierten 'Encyclopedia of Biostatistics'. Dieser Band enthält 25% neues Material, umfassend aktualisierte Artikel und Verweise aus der Enzyklopädie sowie prägnante Definitionen und Einführungen in zahlreiche Grundlagen aus der aktuellen Literatur. Darüber hinaus wird eine Reihe neuer Themen behandelt, wie z.B. Bayesche Methoden, ethische Fragen und die Nutzen-Risiko-Bewertung. Durch umfangreiche Querverweise findet der Leser rasch Definitionen und verwandte Konzepte .