Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials. - Customized presentation for biological investigators with examples taken from current clinical trials in multiple disciplines - Clear and concise definitions and examples provide a pragmatic guide to bring clarity to the applications of statistics in improving human health - Addresses the challenge of assimilation of mathematical concepts to better interpret literature, to build stronger studies, to present research effectively, and to improve communication with supporting biostatisticians

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures. This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares. Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research. Is illustrated throughout with simple examples to clarify the statistical methodology. Explains Bayes’ theorem pictorially. Features exercises, with answers to alternate questions, enabling use as a course text. Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

Basic Biostatistics is a concise, introductory text that covers biostatistical principles and focuses on the common types of data encountered in public health and biomedical fields. The text puts equal emphasis on exploratory and confirmatory statistical methods. Sampling, exploratory data analysis, estimation, hypothesis testing, and power and precision are covered through detailed, illustrative examples. The book is organized into three parts: Part I addresses basic concepts and techniques; Part II covers analytic techniques for quantitative response variables; and Part III covers techniques for categorical responses. The Second Edition offers many new exercises as well as an all new chapter on "Poisson Random Variables and the Analysis of Rates." With language, examples, and exercises that are accessible to students with modest mathematical backgrounds, this is the perfect introductory biostatistics text for undergraduates and graduates in various fields of public health. Features: Illustrative, relevant examples and exercises incorporated throughout the book. Answers to odd-numbered exercises provided in the back of the book. (Instructors may requests answers to even-numbered exercises from the publisher. Chapters are intentionally brief and limited in scope to allow for flexibility in the order of coverage. Equal attention is given to manual calculations as well as the use of statistical software such as StaTable, SPSS, and WinPepi. Comprehensive Companion Website with Student and Instructor's Resources.

*Customized presentation for biological investigators with examples taken from current clinical trials in multiple disciplines.

This practical guide to survival data and its analysis for readers with a minimal background in statistics shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts as bias, confounding, independence, and interaction are presented in the context of survival analysis and also are basic components of a broad range of applications. These topics make up essentially a 'second-year', one-semester biostatistics course in survival analysis concepts and techniques for non-statisticians.

Analyze your biostatistics data with JMP! Trevor Bihl's Biostatistics Using JMP: A Practical Guide provides a practical introduction on using JMP, the interactive statistical discovery software, to solve biostatistical problems. Providing extensive breadth, from summary statistics to neural networks, this essential volume offers a comprehensive, step-by-step guide to using JMP to handle your data. The first biostatistical book to focus on software, Biostatistics Using JMP discusses such topics as data visualization, data wrangling, data cleaning, histograms, box plots, Pareto plots, scatter plots, hypothesis tests, confidence intervals, analysis of variance, regression, curve fitting, clustering, classification, discriminant analysis, neural networks, decision trees, logistic regression, survival analysis, control charts, and metaanalysis. Written for university students, professors, those who perform biological/biomedical experiments, laboratory managers, and research scientists, Biostatistics Using JMP provides a practical approach to using JMP to solve your biostatistical problems.

Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology

Learn biostatistics the easy way. This outstanding resource presents the key concepts you need to understand biostatistics and how to apply them in clinical medicine. Easy-to-understand examples and analogies explain complex concepts, and practical applications provide you with real tools for use in daily practice. The book's organization is intuitive, so that concepts build upon one another, maximizing understanding. This book will give you the confidence to appraise the existing literature - and the vocabulary you need to discuss it. - Uses an easy-to-understand presentation and writing style to make the material easily accessible. - Places its emphasis on concepts, not formulas, for more clinical-based guidance. - Focuses on practical applications of biostatistics to medical practice to give you a better understanding of how and why research is conducted. - Presents concise but comprehensive coverage to create easily accessible yet complete information. - Provides examples, analogies, and memorization tips to make the material easier to absorb.

This book focuses on novel approaches that provide a reliable basis for identifying which patients are likely to benefit from each treatment. Aimed at both clinical investigators and statisticians, it covers the development and validation of prognostic and predictive biomarkers and their integration into clinical trials.

Focuses on the prevention and treatment of missing data in longitudinal clinical trials, looking at key principles and explaining analytic methods.