Microbiome and Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America

In this first-of-its-kind issue of Rheumatic Disease Clinics, guest editor Dr. Bryant R. England brings his considerable expertise to the topic of Environmental Triggers for Rheumatic Diseases. In practical, state-of-the-art articles, top experts examine the connection between some of the most commonly seen rheumatic disease and environmental triggers for the disease. Contains 13 practice-oriented topics including inhalant and mucosal-related environmental risks for rheumatoid arthritis; lifestyle, hormonal, and microbial-related environmental risks for rheumatoid arthritis; environmental risks for systemic lupus erythematosus; environmental risks for osteoarthritis; targeting environmental risks to prevent rheumatic diseases; and more. Provides in-depth clinical reviews on environmental triggers for rheumatic diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Rheumatic Disease Clinics will include articles such as: Vaccines and Biologics- efficacy and toxicity; Improving Vaccine administration in Practice; HCV and rheumatology; HBV reactivation and rheumatic disease; Herpes zoster in rheumatic diseases; Opportunistic infections in biologic therapy, risk and prevention; and many more!

Guest edited by Drs. Jonathan Kay and Sergio Schwartzman, this issue of Rheumatic Disease Clinics will cover Controversies in Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles explore several questions, including, but not limited to: Is triple therapy or methotrexate plus a biologic the initial treatment of choice for RA patients; Is hypo or hyper-uricemia a risk requiring treatment for cardiac morbidity and mortality; Are there benefits and risks to biosimilars from a patient perspective; Should platelet-rich plasma be used to treat osteoarthritis; Is there a role for stem cell therapy to treat cartilage defects in osteoarthritis; Should any rheumatology patient, today, be treated with bone marrow ablation and stem cell transplantation; Is there effective prevention, prophylaxis, or treatment for CPPD arthritis; Is fibromyalgia a psychiatric disease or a pain syndrome; Should cyclophosphamide still be used to treat ANCA-associated vasculitis; Does methotrexate have a place in the treatment of psoriatic arthritis; Should hydroxychloroquine dosing be limited because of potential ocular toxicity; and Should generalized immunosuppression or targeted organ treatment be the best principle for overall management of SLE.

In this first-of-its-kind issue of Rheumatic Disease Clinics, guest editor Dr. Bryant R. England brings his considerable expertise to the topic of Environmental Triggers for Rheumatic Diseases. In practical, state-of-the-art articles, top experts examine the connection between some of the most commonly seen rheumatic disease and environmental triggers for the disease. Contains 13 practice-oriented topics including inhalant and mucosal-related environmental risks for rheumatoid arthritis; lifestyle, hormonal, and microbial-related environmental risks for rheumatoid arthritis; environmental risks for systemic lupus erythematosus; environmental risks for osteoarthritis; targeting environmental risks to prevent rheumatic diseases; and more. Provides in-depth clinical reviews on environmental triggers for rheumatic diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Rheumatic Disease Clinics, guest editor Dr. Erin Janssen brings her considerable expertise to the topic of New and Emerging Rheumatic Diseases. Top experts in the field cover issues such as approach to diagnosing in-born errors of immunity; Type I interferonopathies; SOCS1 and immune dysregulation; manifestations of DADA2; COPA syndrome; and more. - Contains 15 relevant, practice-oriented topics including T cell tolerance/Treg defects; gene defects in early onset IBD/colitis; autoimmunity with cytoskeletal d/o - WAS, DOCK8; autoimmune and autoinflammatory neurologic conditions; genes in HLH and that predispose to MAS; mutations in severe COVID/MISC; and more. - Provides in-depth clinical reviews on new and emerging rheumatic diseases, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Guest edited by Drs. Daniel J. Wallace and R. Swamy Venuturupalli, this issue of Rheumatic Disease Clinics will cover several key areas of interest related to Best Practices and Challenges to the Practice of Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles in this issue include, but are not limited to: The Economics of Rheumatology Practice in the United States, Manpower trends in rheumatology, Challenges to practicing rheumatology in an academic center, Challenges in practicing rheumatology in a government setting, Challenges to practicing rheumatology in a small private practice setting, Challenges to working in a large multispecialty organization, Challenges to practicing pediatric rheumatology, Clinical trials in rheumatology, Challenges in having an infusion center, Implementing treatment to target in the clinic, Future directions: implementing new technologies in clinical practice, Possible Challenges in Optimizing Medical Education for Rheumatologists, and the challenges of approaching and managing gout.

Guest edited by Dr. Brian Mandell, this issue of Medical Clinics of North America will cover several key areas of interest related to Rheumatology. This issue is one of six selected each year by our series Consulting Editor, Dr. Jack Ende. Articles in this issue include but are not limited to: Vaccinations in Patients with Rheumatic Disease: Consider Disease and Therapy, Rheumatic Complications of Immune Checkpoint Inhibitors, Managing the Cardiovascular Risk in Patients with Rheumatic Disease, Statin associated myalgias and muscle injury – recognizing and managing both while still lowering the low-density lipoprotein, Perioperative Management of Rheumatic Disease and Therapies, Fibromyalgia: Recognition and Management in the Primary Care Office, Management and Cure of Gouty Arthritis, Update on the Treatment of Giant Cell Arteritis and Polymyalgia Rheumatica, Suspecting and Diagnosing the Patient with Spondyloarthritis and What to Expect from Therapy, Pregnancy and Management in Women with Rheumatoid Arthritis, Systemic Lupus Erythematosus and Obstetrical Antiphospholipid Syndrome, Rheumatoid Arthritis: Early Diagnosis and Treatment, Management of Knee Osteoarthritis: What Internists Need to Know, Antinuclear antibody (ANA) testing for the diagnosis of Systemic Lupus Erythematosus (SLE), and more.

This issue of Rheumatic Disease Clinics, guest edited by Drs. Karina Torralba and James D. Katz, will discuss Education and Professional Development in Rheumatology. This issue is one of four each year selected by our series consulting editor, Dr. Michael Weisman. Articles in this issue include, but are not limited to: From Classroom to Clinic: Clinical Reasoning via Active Learning Strategies; Self-directed Learning of Musculoskeletal Ultrasound for clinicians in practice; Enhancing the inpatient consult service with the Fellow as a Teacher; Translating Quality Improvement in Education to clinical practice; Beyond Class-Rheum: Applying Clinical Epidemiology into Practice; Ethics and Industry Interactions: Impact on Specialty Training, Clinical Practice and Research; Mind the Gap: Improving Care in Pediatric-to-Adult Rheumatology Transitional Clinics; Underserved Communities: Enhancing care with Graduate Medical Education; Turning OSCE into reality; Online Resources for Enhancing Clinical Skills; and Addressing Health Disparities in Medical Education and Clinical Practice.

This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.