This book introduces some basic mathematical tools in reaction-diffusion models, with applications to spatial ecology and evolutionary biology. It is divided into four parts. The first part is an introduction to the maximum principle, the theory of principal eigenvalues for elliptic and periodic-parabolic equations and systems, and the theory of principal Floquet bundles. The second part concerns the applications in spatial ecology. We discuss the dynamics of a single species and two competing species, as well as some recent progress on N competing species in bounded domains. Some related results on stream populations and phytoplankton populations are also included. We also discuss the spreading properties of a single species in an unbounded spatial domain, as modeled by the Fisher-KPP equation. The third part concerns the applications in evolutionary biology. We describe the basic notions of adaptive dynamics, such as evolutionarily stable strategies and evolutionary branching points, in the context of a competition model of stream populations. We also discuss a class of selection-mutation models describing a population structured along a continuous phenotypical trait. The fourth part consists of several appendices, which present a self-contained treatment of some basic abstract theories in functional analysis and dynamical systems. Topics include the Krein-Rutman theorem for linear and nonlinear operators, as well as some elements of monotone dynamical systems and abstract competition systems. Most of the book is self-contained and it is aimed at graduate students and researchers who are interested in the theory and applications of reaction-diffusion equations.

By using mathematical models to describe the physical, biological or chemical phenomena, one of the most common results is either a differential equation or a system of differential equations, together with the correct boundary and initial conditions. The determination and interpretation of their solution are at the base of applied mathematics. Hence the analytical and numerical study of the differential equation is very much essential for all theoretical and experimental researchers, and this book helps to develop skills in this area.Recently non-linear differential equations were widely used to model many of the interesting and relevant phenomena found in many fields of science and technology on a mathematical basis. This problem is to inspire them in various fields such as economics, medical biology, plasma physics, particle physics, differential geometry, engineering, signal processing, electrochemistry and materials science.This book contains seven chapters and practical applications to the problems of the real world. The first chapter is specifically for those with limited mathematical background. Chapter one presents the introduction of non-linear reaction-diffusion systems, various boundary conditions and examples. Real-life application of non-linear reaction-diffusion in different fields with some important non-linear equations is also discussed. In Chapter 2, mathematical preliminaries and various advanced methods of solving non-linear differential equations such as Homotopy perturbation method, variational iteration method, exponential function method etc. are described with examples.Steady and non-steady state reaction-diffusion equations in the plane sheet (chapter 3), cylinder (chapter 4) and spherical (chapter 5) are analyzed. The analytical results published by various researchers in referred journals during 2007-2020 have been addressed in these chapters 4 to 6, and this leads to conclusions and recommendations on what approaches to use on non-linear reaction-diffusion equations.Convection-diffusion problems arise very often in applied sciences and engineering. Non-linear convection-diffusion equations and corresponding analytical solutions in various fields of chemical sciences are discussed in chapter6. Numerical methods are used to provide approximate results for the non-linear problems, and their importance is felt when it is impossible or difficult to solve a given problem analytically. Chapter 7 identifies some of the numerical methods for finding solutions to non-linear differential equations.

This work considers a small random perturbation of alpha-stable jump type nonlinear reaction-diffusion equations with Dirichlet boundary conditions over an interval. It has two stable points whose domains of attraction meet in a separating manifold with several saddle points. Extending a method developed by Imkeller and Pavlyukevich it proves that in contrast to a Gaussian perturbation, the expected exit and transition times between the domains of attraction depend polynomially on the noise intensity in the small intensity limit. Moreover the solution exhibits metastable behavior: there is a polynomial time scale along which the solution dynamics correspond asymptotically to the dynamic behavior of a finite-state Markov chain switching between the stable states.

This book presents several fundamental results in solving nonlinear reaction-diffusion equations and systems using symmetry-based methods. Reaction-diffusion systems are fundamental modeling tools for mathematical biology with applications to ecology, population dynamics, pattern formation, morphogenesis, enzymatic reactions and chemotaxis. The book discusses the properties of nonlinear reaction-diffusion systems, which are relevant for biological applications, from the symmetry point of view, providing rigorous definitions and constructive algorithms to search for conditional symmetry (a nontrivial generalization of the well-known Lie symmetry) of nonlinear reaction-diffusion systems. In order to present applications to population dynamics, it focuses mainly on two- and three-component diffusive Lotka-Volterra systems. While it is primarily a valuable guide for researchers working with reaction-diffusion systems and those developing the theoretical aspects of conditional symmetry conception, parts of the book can also be used in master’s level mathematical biology courses.

Modeling and analyzing the dynamics of chemical mixtures by means of differ- tial equations is one of the prime concerns of chemical engineering theorists. These equations often take the form of systems of nonlinear parabolic partial d- ferential equations, or reaction-diffusion equations, when there is diffusion of chemical substances involved. A good overview of this endeavor can be had by re- ing the two volumes by R. Aris (1975), who himself was one of the main contributors to the theory. Enthusiasm for the models developed has been shared by parts of the mathematical community, and these models have, in fact, provided motivation for some beautiful mathematical results. There are analogies between chemical reactors and certain biological systems. One such analogy is rather obvious: a single living organism is a dynamic structure built of molecules and ions, many of which react and diffuse. Other analogies are less obvious; for example, the electric potential of a membrane can diffuse like a chemical, and of course can interact with real chemical species (ions) which are transported through the membrane. These facts gave rise to Hodgkin's and Huxley's celebrated model for the propagation of nerve signals. On the level of populations, individuals interact and move about, and so it is not surprising that here, again, the simplest continuous space-time interaction-migration models have the same g- eral appearance as those for diffusing and reacting chemical systems.

The book is about reaction-diffusion equations in unbounded domains with a special emphasis on traveling waves and their generalizations as well as on different notions of propagation. It includes a general presentation of all the classical results in this area. Even for some well known results, in some cases, original proofs are included which are simpler and more elegant than the known ones. The book gives a fairly comprehensive and coherent account of the recent developments and current research in this active area. It also contains some of the basic results about elliptic and parabolic partial differential equations and a chapter on the different versions of the maximum principles. Thus, it also serves as an introduction to these topics. Each chapter is made as much autonomous as possible. Each one has a specific introduction as well as brief mentions of extensions or of related subjects. Some outstanding open problems are mentioned along the way. Each introduction states the goals of the chapter, some of its main results, the framework and indicates how the chapter is organized. The book is addressed to researchers and graduate students in mathematics, in particular in analysis, partial differential equations and applied mathematics. It will be of interest as well to researchers and graduate students concerned by mathematical modeling in physics and in biology. It is planed to be a reference book of lasting value with all the important results on a topic which is commonly used in these fields.

This practical introduction to stochastic reaction-diffusion modelling is based on courses taught at the University of Oxford. The authors discuss the essence of mathematical methods which appear (under different names) in a number of interdisciplinary scientific fields bridging mathematics and computations with biology and chemistry. The book can be used both for self-study and as a supporting text for advanced undergraduate or beginning graduate-level courses in applied mathematics. New mathematical approaches are explained using simple examples of biological models, which range in size from simulations of small biomolecules to groups of animals. The book starts with stochastic modelling of chemical reactions, introducing stochastic simulation algorithms and mathematical methods for analysis of stochastic models. Different stochastic spatio-temporal models are then studied, including models of diffusion and stochastic reaction-diffusion modelling. The methods covered include molecular dynamics, Brownian dynamics, velocity jump processes and compartment-based (lattice-based) models.

Although the book is largely self-contained, some knowledge of the mathematics of differential equations is necessary. Thus the book is intended for mathematicians who are interested in the application of their subject to the biological sciences and for biologists with some mathematical training. It is also suitable for postgraduate mathematics students and for undergraduate mathematicians taking a course in mathematical biology. Increasing use of mathematics in developmental biology, ecology, physiology, and many other areas in the biological sciences has produced a need for a complete, mathematical reference for laboratory practice. In this volume, biological scientists will find a rich resource of interesting applications and illustrations of various mathematical techniques that can be used to analyze reaction-diffusion systems. Concepts covered here include:**systems of ordinary differential equations**conservative systems**the scalar reaction-diffusion equation**analytic techniques for systems of parabolic partial differential equations**bifurcation theory**asymptotic methods for oscillatory systems**singular perturbations**macromolecular carriers -- asymptotic techniques.