This issue of Radiologic Clinics of North America focuses on Imaging of the Reproductive Age Female, and is edited by Dr. Liina Poder. Articles will include: Imaging Safety and Technical Considerations in the Reproductive Age Female; Imaging of Infertility: Hysterosalpingograms to MRI; Imaging Spectrum of Benign Uterine Disease and Treatment Options; Imaging of Benign Adnexal Disease; Imaging Spectrum of Endometriosis (Endometriomas to Deep Infiltrative Endometriosis); Imaging of The Female Pelvic Floor: Current Implications and New Horizons; Imaging of Acute Pelvic Pain: Nonpregnant; Imaging of Acute Pelvic Pain: Pregnant (ectopic and first trimester viability updated); Nonfetal Imaging During Pregnancy: Acute Abdomen/Pelvis; Nonfetal Imaging During Pregnancy: Placental Related Disease; Imaging of Gynecologic Malingancy in a Reproductive Age Female: Fertility Sparing; Imaging of Gynecologic Malignancy in A Reproductive Age Female: Cancer During Pregnancy; Imaging of Post/Peripartum Complications; Role of Interventional Procedures in Obstetrics and Gynecology, and more!

This issue of Radiologic Clinics of North America focuses on Imaging of the Reproductive Age Female, and is edited by Dr. Liina Poder. Articles will include: Imaging Safety and Technical Considerations in the Reproductive Age Female; Imaging of Infertility: Hysterosalpingograms to MRI; Imaging Spectrum of Benign Uterine Disease and Treatment Options; Imaging of Benign Adnexal Disease; Imaging Spectrum of Endometriosis (Endometriomas to Deep Infiltrative Endometriosis); Imaging of The Female Pelvic Floor: Current Implications and New Horizons; Imaging of Acute Pelvic Pain: Nonpregnant; Imaging of Acute Pelvic Pain: Pregnant (ectopic and first trimester viability updated); Nonfetal Imaging During Pregnancy: Acute Abdomen/Pelvis; Nonfetal Imaging During Pregnancy: Placental Related Disease; Imaging of Gynecologic Malingancy in a Reproductive Age Female: Fertility Sparing; Imaging of Gynecologic Malignancy in A Reproductive Age Female: Cancer During Pregnancy; Imaging of Post/Peripartum Complications; Role of Interventional Procedures in Obstetrics and Gynecology, and more!

This book concisely covers the latest developments in the application of direct oral anticoagulants (DOACs) within cardiovascular medicine. It details the pharmacodynamics and pharmacokinetic mechanisms of DOACs and their application in treating patients with conditions ranging from coronary heart disease through kidney disease and cancer, including their perioperative management. Direct Oral Anticoagulants: From Pharmacology to Clinical Practice systematically describes the underlying mechanisms associated with DOACs and their use to treat a range of conditions and is an indispensable resource for all trainee and practicing physicians in a range of disciplines seeking a concise up-to-date resource on the topic.

The Handbook of Small Animal Radiology and Ultrasound: Techniques and Differential Diagnoses provides a user-friendly reference for a wide range of radiographic and ultrasonographic findings in dogs and cats. Key features Enables successful and clear interpretation of radiographs and ultrasonograms Offers clearly sequenced text arrangement from the identification of the radiographic or sonographic abnormalities to a list of subsequent considerations for each sign Prioritizes different clinical findings to tailor further diagnostic tests or therapeutic interventions Takes imaging abnormalities from the descriptive to the interpretative New to this edition Colour throughout enhances user-friendliness Many new conditions Extra illustrations show techniques and normal anatomy Additional information on techniques, normal appearance and disease processes Expanded Further Reading sections This book is intended for all users of small animal diagnostic imaging, from radiologists through to general practitioners to veterinary students, and will be an invaluable supplement to existing references in the subject.

In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42. - Written and edited by highly experienced, board-certified toxicologic pathologists - Includes more than 700 high-resolution microscopic images from organs that are typically examined in safety assessment toxicology studies - Detailed figure legends and chapter narratives present the salient features of each organ at each time interval - Figures are available for further study via Elsevier's Virtual Microscope, which allows viewing of microscopic images at higher magnification - Valuable resource for toxicologic pathologists who are confronted with interpretation of lesions in juvenile rats in situations where age-matched concurrent controls are not available for comparison, e.g., with unscheduled decedents - Figures are available for further study on ScienceDirect with Virtual Microscope, which allows viewing of microscopic images at higher magnification

Pediatric osteology, a medical specialty that has come of age, has contributed to the understanding of adult bone diseases as well. This second edition reference updates the 2003 edition with more emphasis on management as well as new and revised contributions. Thirty chapters present basic information regarding bone development, tools and techniques for evaluation (including a new chapter on radiographic imaging), and the specifics of various diseases. The three editors are affiliated as follows: Francis H. Glorieux (McGill U., Canada), John M. Pettifor (Chir Hani Baragwanath Hospital, South Africa), and Harald Juppner (Harvard Medical School, US). Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).

Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text covers the full range of obstetric and gynecologic pathology, including information on treatment and patient management. Written largely by the pathology and clinical faculty at Harvard's Brigham and Women's Hospital, it covers the most up-to-date information available in the field, including molecular genetics and diagnostics. Drs. Christopher P. Crum and Marisa R. Nucci are joined by new editors Scott R. Granter, Brooke E. Howitt, Mana M. Parast, and Theonia K. Boyd, to provide complete, beautifully illustrated coverage of both neoplastic and non-neoplastic disorders of the female genital system, ideal for improving pathological diagnosis. - Provides distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice. - Features more than 2,250 full-color images, key points at the end of each chapter, and an appendix with commonly used ICD-10 codes - Covers topics not often found in gynecologic pathology textbooks, such as vulvodynia, and diseases of the anus. - Approaches topics from a practice-oriented point of view, beginning with clinical presentation and progressing through histopathology, differential diagnosis, and treatment for each disorder. - Emphasizes new practice issues and their biologic basis including approaches to vulvar, cervical and endometrial precursors as well as the underpinnings of cervical, endometrial and ovarian cancer. - A comprehensive look at mesenchymal neoplasia, including not only lower genital tract and uterus but also the retroperitoneum. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource. - Illustrated with over a hundred black and white and color images to assist understanding - Contains detailed descriptions and explanations to accompany all images helping with self-study - Designed for toxicologic research for people from diverse backgrounds including biochemistry, pharmacology, physiology, immunology, and general biomedical sciences

Covering a comprehensive range of common, rare, benign and malignant lesions, Pathology of the Female Reproductive Tract, 3rd Edition, authored by an international panel of subspecialty experts, brings you the latest scientific and diagnostic information for diseases of the female reproductive tract. From basic concepts of pathophysiology and diagnostic criteria to clinical correlation, this updated medical reference book delivers an integrated and practical approach to diagnosis and management of women with reproductive tract disorders. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Quickly and easily access key information with user-friendly bullet points, diagnostic flowcharts, decision-making algorithms, summary tables, and take-home messages, as well as a "Road Map" at the beginning of each chapter for effortless navigation. - Avoid diagnostic errors with the help of practical, expert advice on common pitfalls in differential diagnosis. - Take optimal advantage of the most recent and clinically useful ancillary diagnostic methods, including molecular biomarkers, immunohistochemistry, and genetic studies. - Provide the most accurate and up-to-date diagnostic and prognostic indicators possible by familiarizing yourself with the latest classification and staging systems for all diseases and disorders of the female genital tract. - Stay completely current on the latest histological and molecular standards for diagnosis and prognosis. - Clearly visualize the appearance of each tumor or tumor-like lesion being discussed through improved and updated images.