Pediatric osteology, a medical specialty that has come of age, has contributed to the understanding of adult bone diseases as well. This second edition reference updates the 2003 edition with more emphasis on management as well as new and revised contributions. Thirty chapters present basic information regarding bone development, tools and techniques for evaluation (including a new chapter on radiographic imaging), and the specifics of various diseases. The three editors are affiliated as follows: Francis H. Glorieux (McGill U., Canada), John M. Pettifor (Chir Hani Baragwanath Hospital, South Africa), and Harald Juppner (Harvard Medical School, US). Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).

The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.

There has been a rapid expansion of knowledge in the field of paediatric calcium and bone disorders over the past twenty years. Advances have been made in the underlying genetic basis for many conditions in conjunction with progress in bone density and geometry imaging and the development of new treatment options. The 2nd revised edition of ‘Calcium and Bone Disorders in Children and Adolescents’ presents up-to-date information on many aspects included in the 1st edition such as the physiology, pathology, diagnosis and management of numerous conditions including a chapter of case histories illustrating clinical aspects. New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. Providing a comprehensive update, this book is a useful clinical resource for paediatricians and specialists in endocrinology, metabolic bone disease, nephrology, rheumatology, radiology, orthopaedics and clinical genetics who may be faced with a child with a calcium and/or bone disorder.

Specific operative and nonoperative techniques and their results are stressed. The book is extensively illustrated with drawings, most of which were made for this book, microscopy photos, and serial radiographs. The reader learns of pediatric orthopedic deformity in relation to normal and abnormal developmental biology, the worsening of untreated disease with growth, and the diagnostic and treatment interventions required based on the stage of progression.* Treatments are correlated with the pathologic state of the disorder* Discusses disorders from earliest onset to the final state showing how the altered biology leads to progressively greater clinical deformity* Initial chapter focuses on development bone biology stressing a broad based approach involving histologic, gene and molecular, and biomechanical features* Subsequent chapters discuss the pathogenesis of the various deformities, natural history, radiographic and imaging findings and orthopaedic and surgical management

No other book covers the pathology of the bone marrow in children as extensively as Pediatric Bone Marrow. It provides a wide background for the understanding of bone marrow disease in children and its difference from that of the adult population. The text illustrates the morphology of the peripheral blood, bone marrow aspirate and bone marrow biopsy. It is useful for the diagnosis of pediatric disorders in the bone marrow, making it an ideal guide for pediatric pathologists, hematologists, oncologists and medical technologists or any physician involved in the diagnosis of pediatric bone marrow disorders.

This book is a comprehensive and up-to-date compendium on all aspects of sarcomas of bone and soft tissues in childhood and adolescence. After introductory chapters on the history, epidemiology, and biology of pediatric sarcomas, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. The pathology and biology of this diverse group of tumors are extensively reviewed. Promising new treatment approaches are discussed, and strategies for the development of new agents are appraised. The major common pediatric sarcomas, including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma, are covered in detail. The authors are internationally recognized experts who offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of childhood and adolescent sarcomas and will prove invaluable to specialists, generalists, and trainees alike.

This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.

This book is an indispensable reference for pediatric and musculoskeletal radiologists, as well as orthopedic surgeons. It offers in depth analysis of pediatric orthopedic imaging, covering normal and aberrant development as well as both common and unusual pediatric disorders. Chapters on the spine, shoulder, elbow, hand and wrist, hip and pelvis, lower extremity, and foot and ankle address site-specific congenital and acquired lesions. Subsequent chapters cover generalized orthopedic diseases such as neurofibromatosis and osteogenesis imperfecta, infectious processes, neuromuscular diseases, musculoskeletal tumors, trauma, and orthopedic procedures. The chapters review associated epidemiology, clinical presentation and evolution, treatment, and differential diagnoses, with in-depht analysis of imaging characteristics. With more than 1800 images, high-quality MRI, CT, and US examples complement the radiographs of a broad variety of musculoskeletal disorders.

In the past, determination of bone maturity relied on visual evaluation of skeletal development in the hand and wrist, most commonly using the Greulich and Pyle atlas. The Gilsanz and Ratib digital atlas takes advantage of digital imaging and provides a more effective and objective approach to assessment of skeletal maturity. The atlas integrates the key morphological features of ossification in the bones of the hand and wrist and provides idealized, sex- and age-specific images of skeletal development New to this revised second edition is a description and user manual for Bone Age for iPad®, iPhone® and iPod touch®, which can be purchased and used separately from this book. The App can be easily employed to calculate the deviation of the patient’s age from the normal range and to predict a possible growth delay. This easy-to-use atlas and the related App will be invaluable for radiologists, endocrinologists, and pediatricians and also relevant to forensic physicians.

​The Pediatric Foot and Ankle is a comprehensive overview of the current evaluation, diagnosis, and management strategies for various foot and ankle disorders in the pediatric patient. It begins with a general history and physical and radiographic exam of the child’s lower extremity to establish normal parameters. Specific disorders are then described in detail, including neurological abnormalities, congenital deformities, and traumatic episodes. Expert authors in each area not only provide their insight and experience for proper diagnosis and treatment, but also proffer available evidence-based medicine on the topic. Since there is currently very little available to the surgeon regarding pediatric foot and ankle surgery, this book is a comprehensive authority on the topic, providing both surgical pearls and evidence-based medicine.