Describes dynamic state of metabolic systems, while paving the way for fully predictive modeling frameworks.

Integrating recent research on the physiology and modelling of bioreactions and bioreactors, the authors present a comprehensive, unified introduction to the principles and practices of the field. The work features nearly 100 detailed design examples and problems, many of which are suitable for hands-on demonstrations on a personal computer or for expanded research. The text will serve as a highly instructive guide for students in bioengineering and biotechnology, as well as biochemical, chemical, and environmental engineering.

Alongside presenting the fundamentals, this book reviews the state of the art of mathematical modeling and control of bioprocesses, while demonstrating the application in various biological systems important to industry. At the same time, the application of different types of models and control strategies are illustrated, taking into account the recent developments in reactor modeling. In addition to modeling and control, the metabolic flux analysis and the metabolic design and their application to bioprocesses are considered.

The present text is a complete revision of the 2nd edition from 2003 of the book with the same title. In recognition of the fast pace at which biotechnology is moving we have rewritten several chapters to include new scientific progress in the field from 2000 to 2010. More important we have changed the focus of the book to support its use, not only in universities, but also as a guide to design new processes and equipment in the bio-industry. A new chapter has been included on the prospects of the bio-refinery to replace many of the oil- and gas based processes for production of especially bulk chemicals. This chapter also serves to make students in Chemical Engineering and in the Bio-Sciences enthusiastic about the whole research field. As in previous editions we hope that the book can be used as textbook for classes, even at the undergraduate level, where chemical engineering students come to work side by side with students from biochemistry and microbiology. To help the chemical engineering students Chapter 1 includes a brief review of the most important parts of microbial metabolism. In our opinion this review is sufficient to understand microbial physiology at a sufficiently high level to profit from the rest of the book. Likewise the bio-students will not be overwhelmed by mathematics, but since the objective of the book is to teach quantitative process analysis and process design at a hands-on level some mathematics and model analysis is needed. We hope that the about 100 detailed examples and text notes, together with many instructive problems will be sufficient to illustrate how model analysis is used, also in Bio-reaction Engineering.

This book is a printed edition of the Special Issue "Feature Papers for Celebrating the Fifth Anniversary of the Founding of Processes" that was published in Processes

"Optimization for Chemical and Biochemical Engineering - Theory, Algorithms, Modeling and Applications"--

The go-to guide to learn the principles and practices of design and analysis in chemical engineering.

Discover tools to perform Life Cycle Analysis (LCA) and develop sustainable chemical technologies in this valuable guide for chemists, engineers and practitioners. Tackling one of the key challenges of modern industrial chemical engineering, this book introduces tools to assess the environmental footprint and economics of key chemical processes that make the ingredients of everyday products such as plastics, synthetic fibers, detergents and fuels. Describing diverse industrial processes in detail, it provides process flow diagrams including raw material sourcing, catalytic reactors, separation units, process equipment and recycle streams. The book clearly explains elements of LCA and how various software tools, available in the public domain and commercially, can be used to perform LCA. Supported by real-world practical examples and case studies provided by industrial and academic chemists and chemical engineers, this is an essential tool for readers involved in implementing LCA, and developing next-generation sustainable chemical technologies.

A unique text covering basic and advanced concepts of optimization theory and methods for process systems engineers. With examples illustrating key concepts and algorithms, and exercises involving theoretical derivations, numerical problems and modeling systems, it is ideal for single-semester, graduate courses in process systems engineering.

This book is a printed edition of the Special Issue "Microbial Community Modeling: Prediction of Microbial Interactions and Community Dynamics" that was published in Processes