The new edition of this atlas integrates all significant advances made in the past 15 years in molecular pathology, tumor virology, and genetics of cervical cancer. It emphasizes the importance of these advances in facilitating its pathological diagnosis and in op- mizing clinical management and prognosis. A new chapter on immunohistochemistry has been added, which includes refined detection methods, e. g., the overexpression of INK4a p16 as a molecular marker in the early differential diagnosis of premalignant - sions. The section on etiology and pathogenesis in human papillomavirus-induced neoplasia has been incorporated to represent new insights into the sequences of cel- lar and nuclear deregulation at the molecular level. All chapters have been revised to - clude the newest advances and relevant experiences in how to interpret and manage cervical disease; they are supported by the addition of 35 new microphotographic ill- trations. The tumor nomenclature is adapted to the latest edition of the WHO classi- cation; the morphology code of the international classification of diseases for oncology (ICD-O) has been added. We have also updated the list of references by adding recent relevant publications. Again, the staff of Springer-Verlag deserve our thanks for their patience and skill in preparing the manuscript and in reproducing the microphotographs. Heidelberg, February 2005 Gisela Dallenbach-Hellweg, Magnus von Knebel Doeberitz, and Marcus J. Trunk Heading2 Preface to the First Edition During the past decade our understanding of the histopathology of the cervix uteri has changed greatly.

An atlas covering the normal and pathologic histology of the uterine cervix. Differential diagnosis is given in detail yet related to clinical aspects, so that a functional de- scription of benefit in daily practice is achieved.

Functional description of the entire aspect of the morphologic changes in the uterine cervix taking into consideration cytologic, histpathologic, immunohistochemical and virological findings. There will be specific therapeutic proposals based on an accurate diagnosis. Utilization of other related scientific disciplines such as electron microscopy, endocrinology, biochemistry, cytogenetics will be emphasized. The purpose is a close interdisciplinary cooperation between gynecologists and pathologists.

Complete with over 500 high-quality, full-colour histographs and cytographs, this fourth volume in Dr Shu's gynaecologic cytopathology series provides a complete review of cytopathology of the uterine cervix. It examines the techniques of specimen collection and the diagnostic accuracy of the criteria. Photographs and case studies are selected from a research collection of over 2.5 million pap smears.

This book provides a practical guide to the diagnosis of cervical lesions. Chapters detail recent changes to diagnostic criteria and classification and the impacts these developments have on patient management. The anatomy and histology of the cervix are discussed, along with macroscopic and microscopic changes, prognostic and predictive parameters, epidemiological data, and staging systems. Atlas of Diagnostic Pathology of the Cervix: A Case-Based Approach utilizes diagnostic algorithms and highlights to offer readers appropriate management criteria and aims to give trainees, practicing pathologists, and gynecologists a case-based approach to the treatment of cervical lesions.

This book presents colored gross and microphotographs of histopathology sections of both common and uncommon tumors of the female genital tract, and also includes the immunohistochemistry of the important lesions. Further, it explains the salient diagnostic features and the immunocytochemistry, molecular pathology and differential diagnosis of each lesion with brief references and discusses recent advances in the diagnosis of these tumors. With numerous images offering guidance on diagnosing different lesions of the female genital tract, the book is intended for practicing pathologists and post-graduate students as well as for gynecology practitioners and post-graduate students.

In America and Europe, carbon dioxide has been widely used as the distention medium in hysteroscopy, in contrast to the widespread use of liquid hysteroscopy in Japan. There are merits and demerits for both media, but the author prefers liquid hysteroscopy because of reduced leakage into the abdominal cavity, reduced glare, and improved debris removal. Although TV images captured with a flexible endoscope are employed for routine work, the author insists on using a single-lens reflex camera with a rigid endoscope for producing wonderfully clear photographs. Having carried out between 400 and 550 examinations a year for the last 20 years, the author has built up an impressive library of quintessential diagnostic images. Over 200 of these photographs are reproduced in color in this atlas to provide a visual guide to uterine abnormalities of unparalleled breadth and clarity.