Topics include: Automated external defibrillation, Airway management during CPR, Could we remove ventilation from ABC's of CPR?, Advances in mechanical interventions during CPR, The role of vasopressor agents during CPR, Optimizing the timing of defibrillation: the role of VF waveform analysis during CPR, Therapeutic hypothermia during and after CPR, and Advances in brain resuscitation: beyond hypothermia.

In this issue of Critical Care Clinics, guest editors Drs. David N. Hager, Kyle Gunnerson, and Stephen Macdonald bring their considerable expertise to the topic of Critical Illness Outside the ICU. Top experts cover key topics such as flight transport of the critically ill; models of critical care in the emergency department; in-hospital triage; rapid response teams; early warning systems; ICU without walls; and more. - Contains 14 relevant, practice-oriented topics the role of intermediate care; PACU care; critical care in rural settings; critical care in austere settings; tele-ICU support; alternate care pathways for the patient with multimorbidity; and more. - Provides in-depth clinical reviews on critical illness outside the ICU, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics focuses on Rapid Response Systems and Fluid Resuscitation, with topics including: RRS Now; Triggering Criteria: Big Data; Triggering Criteria: Continuous Monitoring; Measuring instability; Surgery/Trauma RRT; Obstetric RRT; Difficult airway rapid response teams; and Sepsis rapid response teams.

In this issue of Critical Care Clinics, guest editors Drs. Lauren R. Sorce and Joy D. Howell bring their considerable expertise to the topic of Pediatric Critical Care. Top experts in the field cover key topics such as point-of-care ultrasound for pediatric critical care providers; transfusion strategies in the 21st century; global pediatric critical care; workforce diversity; and more. - Contains 13 relevant, practice-oriented topics including pediatric redeployment: unique challenges created by COVID-19; ECMO then and now; PCCM in 21st century and beyond; pediatric critical care outcomes; cardiac output monitoring; and more. - Provides in-depth clinical reviews on pediatric critical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Critical Care Clinics, guest editors Drs. Lori Shutter and Deepa Malaiyandi bring their considerable expertise to the topic of Neurocritical Care, a rapidly growing specialty of complex care. Top experts in the field provide up-to-date articles on important clinical trials and evidence-based care of the critically ill patient with neurological injury. - Contains 16 practice-oriented topics including current management of acute ischemic stroke; status epilepticus: a neurological emergency; neurotrauma and ICP management; neuropharmacology in the ICU; artificial intelligence and big data science in neurocritical care; and more. - Provides in-depth clinical reviews on neurocritical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics, Guest Edited by Dr. Stephen M. Pastores and Dr. Wendy R. Greene, focuses on Critical Care of the Cancer Patient (Pastores) and Geriatric Critical Care (Greene). Dr. Pastores' section of the issue is devoted to Critical Care of the Cancer Patient and includes the following topics: Triage and Prognostication of Cancer Patients Admitted to the ICU; ICU Organization and Interdisciplinary Care for Critically Ill Patients with Cancer; Critical Care of the Hematopoietic Stem Cell Transplant Recipient; Management of Drug Toxicities; Acute Kidney Injury in the Critically Ill Patient with Cancer; Infectious Disease Complications in Cancer Patients; and Palliative, Ethics, and End-of-Life Care Issues in the Cancer Patient. Dr. Green's section of the issue, devoted to Geriatric Critical Care, includes the following topics: The effect of aging physiology on critical care; The frailty syndrome: a critical issue in geriatric oncology; Detection of delirium in the intensive care unit: comparison of confusion assessment method for the intensive care unit with confusion assessment method ratings; Evidence-based geriatric nursing protocols for best practice; The effect of dementia in the critically ill geriatric patient; Nutritional assessment: a primary component of multidimensional geriatric assessment in the ICU; Rehabilitation concerns in the geriatric critically ill and injured; and Geriatric palliative care.

In this issue of Critical Care Clinics, guest editors Drs. Steven Hollenberg and José L. Diaz-Gomez bring their considerable expertise to the topic of Cardiovascular Intensive Care. Top experts cover key topics such as hemodynamic monitoring in the cardiac ICU; the role of ultrasound in the cardiac ICU; cardiogenic shock; management of patients after cardiac arrest; temporary mechanical circulatory support; and more. - Contains 16 relevant, practice-oriented topics including the changing epidemiology of the cardiac intensive care unit; diagnosis and management of LVAD emergencies; design and execution of clinical trials in the CICU; end-of life issues in patients with mechanical circulatory support; and more. - Provides in-depth clinical reviews on cardiovascular intensive care, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Critical Care Clinics, guest edited by Dr. Mitchell M. Levy, focuses on Biomarkers in Critical Care. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: The History of Biomarkers; Biomarkers for Identifying Infection; Procalcitonin: Where Are We Now?; Soluble TREM-1: Diagnosis or Prognosis?; Lubricin as a Biomarker in Sepsis; Check Point Inhibitors and Their Role in Immunosuppression in Sepsis; Metabolomics and the Microbiome as Biomarkers in Sepsis; Lactate: Where Are We Now?; Predicting Renal Dysfunction; Biomarkers in the Evolution of ARDS; Biomarkers and RV Dysfunction; Biomarkers and Precision Medicine: State of the Art; The Use of Biomarkers for Population Homogeneity in Clinical Trials; and The Future of Biomarkers.

This issue of Critical Care Clinics focuses on Mechanical Circulatory Support. Editors Nitin Puri and Michael Baram have assembled an expert team of authors on topics such as: History of ECMO; Evolution current technique and equipment; Program Development; Review ELSO standards; Cardiac Failure of medical management; Cardiac Management and Complications; Pre-Respiratory; Respiratory Management and Complications; Post ECMO management; Post ECMO complication; DVT; Transport- Interhospital and How to prep patient; ECHO; Family understanding of ECMO (to cannulate or not); Pharmacy, Nutrition, Blood Management; Transport; The future of ECMO and ventilation.

Topics include: A Critical re-appraisal of Factor VIIa; Thrombocytopenia: Hit vs non-HIT causes; Transfusion Reactions: Newer concepts on the pathophysiology, incidence, treatment and prevention of TRALI; The utility of diagnostic scoring systems for DIC; Newer anticoagulants; Anemia in the ICU; The role of plasmapheresis in critical illness; The use of erythropoiesis stimulating agents in the ICU; and Coagulopathy in the ICU: DIC vs Liver disease. Is this distinction important?