This issue of Critical Care Clinics focuses on Rapid Response Systems and Fluid Resuscitation, with topics including: RRS Now; Triggering Criteria: Big Data; Triggering Criteria: Continuous Monitoring; Measuring instability; Surgery/Trauma RRT; Obstetric RRT; Difficult airway rapid response teams; and Sepsis rapid response teams.

This issue of Critical Care Clinics, edited by Mervyn singer and Manu Shankar-Hari, includes: Sepsis 3.0 Definitions; Epidemiology and Outcomes; Pathophysiology of sepsis; Pathophysiology of Septic shock; Mechanism of organ dysfunction in sepsis; Endocrine and metabolic alterations in sepsis: challenges and treatments; The immune system in sepsis; Nutrition and Sepsis; Common sense approach to managing sepsis; Biomarkers for sepsis and their use; Personalizing sepsis care; Novel interventions - What’s new and the future; and Long term outcomes following Sepsis.

This issue of Critical Care Clinics focuses on Mechanical Circulatory Support. Editors Nitin Puri and Michael Baram have assembled an expert team of authors on topics such as: History of ECMO; Evolution current technique and equipment; Program Development; Review ELSO standards; Cardiac Failure of medical management; Cardiac Management and Complications; Pre-Respiratory; Respiratory Management and Complications; Post ECMO management; Post ECMO complication; DVT; Transport- Interhospital and How to prep patient; ECHO; Family understanding of ECMO (to cannulate or not); Pharmacy, Nutrition, Blood Management; Transport; The future of ECMO and ventilation.

This issue of Critical Care Clinics focuses on Psychiatric Aspects of Critical Care Medicine. Editor Jose Maldonado has assembled an expert team of authors on topics such as: Psychiatric Aspects of Organ Transplantation in Critical Care; Medical Complications of Psychiatric Treatment; Psychiatric and Palliative Care in the ICU; Psychiatric Aspects of Heart and Lung Disease in Critical Care; Alcohol Withdrawal Syndromes: Assessment and Management; Substance Abuse and Withdrawal in the Critical Care Setting; Mood Disorders and The Outcome of Suicidal Thoughts and Attempts; Anxiety Disorders and the Outcomes of Trauma; Assessment and Management of Toxidromes in the Critical Care Unit; Neuropsychiatric Consequences of Trauma and Head Injury; Detection and Management of Pre-Existing Cognitive Impairment in the Critical Care Unit; Delirium: Pathophysiology, Diagnosis and Treatment; Neuropsychiatric Aspects of Infectious Processes.

Dr. Michael Pinsky has assembled an expert team of authors on the topic of Hemodynamic Monitoring. Articles topics include: The interface between monitoring and physiology at the bedside; Defining goals of resuscitation in the critically ill; Minimally invasive hemodynamic monitoring; Bedside ultrasound for the intensivist; Invasive hemodynamic monitoring; Functional hemodynamic monitoring; Using what you get: dynamic physiological signatures of critical illness; and Effect of organizational issues on resuscitation effectiveness.

In this issue of Critical Care Clinics, guest editors Drs. David N. Hager, Kyle Gunnerson, and Stephen Macdonald bring their considerable expertise to the topic of Critical Illness Outside the ICU. Top experts cover key topics such as flight transport of the critically ill; models of critical care in the emergency department; in-hospital triage; rapid response teams; early warning systems; ICU without walls; and more. - Contains 14 relevant, practice-oriented topics the role of intermediate care; PACU care; critical care in rural settings; critical care in austere settings; tele-ICU support; alternate care pathways for the patient with multimorbidity; and more. - Provides in-depth clinical reviews on critical illness outside the ICU, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The issue of Hospital Medicine Clinics, Guest Edited by Nicholas J. Kenyon and Mithu Molla, will include Management of Hospitalized Patients with Asthma and Chronic Obstructive Lung Disease; The Hospitalized Patient with Acute Pneumonia; Evaluation and Management of the Hospitalized Patient with Interstitial Lung Disease; Triage and Rapid Response Systems in the Hospitalized Patient with Respiratory and Critical Illness; Noninvasive Ventilation and Respiratory Adjuncts in Hospitalized Patients; Mechanical Ventilation in Patients with Decompensated Respiratory Failure; Diagnosis and Management of Pulmonary Embolism in the Hospitalized Patient; Sleep Disorders in the Hospitalized Patient; Palliative Care and Rehabilitation in the Hospitalized Patient with Respiratory Illness; Acquired Malnutrition in the Hospitalized Patient with Respiratory and Critical Illness; and Use of Bedside Ultrasound in the Hospitalized Patient.

Dr. John Kellum has assembled an essential update on the topic of Nephrology as it relates to Critical Care Medicine. Articles include: Diagnostic criteria, Biomarkers for AKI, Sepsis-induced AKI,Drug-induced AKI, Cardio-renal syndrome,Surgery Associated AKI,Contrast-induced AKI, Principles of Fluid Therapy,Fluid composition and clinical effects, Renal replacement therapy, and Understanding acid-base.

Topics include: Cardiac Arrest as a Public Health Concern, Prehospital Cardiac Arrest, Cardiopulmonary Resuscitation, Cardioactive Medications in Cardiac Arrest, Airway Management in Cardiac Arrest, Rapid Response Teams, and Pediatric Cardiac Arrest.

This issue of Critical Care Clinics focuses on Burn Resuscitation in the ICU. Articles include: The Physiologic Basis of Burn Shock and the Need for Aggressive Fluid Resuscitation; The Use of Colloid in Burn Resuscitation; Monitoring and Endpoints of Burn Resuscitation; Vitamin C in Burn Resuscitation; Pediatric Burn Resuscitation; Burn resuscitation in the Austere Environment; Failed Burn resuscitation; and more!