Symposium on Algorithms (ESA '93), held in Bad Honnef, near Boon, in Germany, September 30 - October 2, 1993. The symposium is intended to launchan annual series of international conferences, held in early fall, covering the field of algorithms. Within the scope of the symposium lies all research on algorithms, theoretical as well as applied, that is carried out in the fields of computer science and discrete applied mathematics. The symposium aims to cater to both of these research communities and to intensify the exchange between them. The volume contains 35 contributed papers selected from 101 proposals submitted in response to the call for papers, as well as three invited lectures: "Evolution of an algorithm" by Michael Paterson, "Complexity of disjoint paths problems in planar graphs" by Alexander Schrijver, and "Sequence comparison and statistical significance in molecular biology" by Michael S. Waterman.

This book brings together recent developments in Alzheimer's disease research with related discoveries in the field of cell biology. The book moves between basic cell biological concepts that form the underpinnings of modern Alzheimer's disease research, and current findings about proteins and cellular processes affected by the disease. Divided into three topics, the book addresses (1) protein trafficking, a problem that has become germane to the study of the amyloid precursor protein; (2) phosphorylation, a problem that underlies studies of the pathological transformation of tau to paired helical filaments; and (3) cell death, a pervasive problem in neurodegeneration.

9

The 7th Annual European Symposium on Algorithms (ESA ’99) is held in Prague, Czech Republic, July 16-18, 1999. This continued the tradition of the meetings which were held in – 1993 Bad Honnef (Germany) – 1994 Utrecht (Netherlands) – 1995 Corfu (Greece) – 1996 Barcelona (Spain) – 1997 Graz (Austria) – 1998 Venice (Italy) (The proceedingsof previousESA meetings were publishedas Springer LNCS v- umes 726, 855, 979, 1136, 1284, 1461.) In the short time of its history ESA (like its sister meeting SODA) has become a popular and respected meeting. The call for papers stated that the “Symposium covers research in the use, design, and analysis of ef?cient algorithms and data structures as it is carried out in c- puter science, discrete applied mathematics and mathematical programming. Papers are solicited describing original results in all areas of algorithmic research, including but not limited to: Approximation Algorithms; Combinatorial Optimization; Compu- tional Biology; Computational Geometry; Databases and Information Retrieval; Graph and Network Algorithms; Machine Learning; Number Theory and Computer Algebra; On-line Algorithms; Pattern Matching and Data Compression; Symbolic Computation.

This Festschrift was published in honor of Hans L. Bodlaender on the occasion of his 60th birthday. The 14 full and 5 short contributions included in this volume show the many transformative discoveries made by H.L. Bodlaender in the areas of graph algorithms, parameterized complexity, kernelization and combinatorial games. The papers are written by his former Ph.D. students and colleagues as well as by his former Ph.D. advisor, Jan van Leeuwen. Chapter “Crossing Paths with Hans Bodlaender: A Personal View on Cross-Composition for Sparsification Lower Bounds” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Today the cemented joint prosthesis operation is one of the most frequent procedures in orthopaedic surgery. During the past 30 years the individual steps of such an operation have been carefully validated and thus allow for a reproducible and standardized operation, including a reliable prognosis for the maintenance of the joint. This manual is a practical guide to a complication preventing cementing technique, cement fixation, maintenance of the bone and diamond technique. Clear drawings and diagrams guide the reader through the pre-operative, peri-operative and post-operative steps. The manual covers all possible complications and gives clear instructions, so as to prevent complications but also to cope with them if they occur. Finally, it covers all forensic criteria to be considered.

This volume contains the papers presented at ESA 2009: The 17th Annual - ropean Symposium on Algorithms, September 7–9, 2009. ESA has been held annually since 1993, and seeks to cover both theoretical and engineering aspects of algorithms. The authors were asked to classify their paper under one or more categories as described in Fig. 1. Since 2001, ESA has been the core of the larger ALGO conference, which typically includes several satellite conferences. ALGO 2009 was held at the IT University of Copenhagen, Denmark. The ?ve members of the ALGO 2009 - ganizing Committee were chaired by Thore Husfeldt. The ESA submission deadline was April 12, Easter Sunday. This was clearly an error and we o?er profuse apologies for this mistake. Albeit no excuse, the hard constraints we faced were (a) ICALP noti?cation, April 6, and (b) ESA in Copenhagen, September 7. Between these two endpoints we needed to design a schedule that allowed modifying ICALP rejections for resubmission (1 week), Program Committee deliberations (7 weeks), preparing ?nal versions (4 weeks), and, to prepare, publish, and transport the proceedings (9 weeks). ESA 2009had 272submissions ofwhich 14 werewithdrawn overtime. Of the remaining 222 submissions to Track A (Design and Analysis), 56 were accepted. Of the remaining 36 submissions to Track B (Engineering and Applications), 10 were accepted. This gives an acceptance rate of slightly under 25%.

The 7th Annual European Symposium on Algorithms (ESA ’99) is held in Prague, Czech Republic, July 16-18, 1999. This continued the tradition of the meetings which were held in – 1993 Bad Honnef (Germany) – 1994 Utrecht (Netherlands) – 1995 Corfu (Greece) – 1996 Barcelona (Spain) – 1997 Graz (Austria) – 1998 Venice (Italy) (The proceedingsof previousESA meetings were publishedas Springer LNCS v- umes 726, 855, 979, 1136, 1284, 1461.) In the short time of its history ESA (like its sister meeting SODA) has become a popular and respected meeting. The call for papers stated that the “Symposium covers research in the use, design, and analysis of ef?cient algorithms and data structures as it is carried out in c- puter science, discrete applied mathematics and mathematical programming. Papers are solicited describing original results in all areas of algorithmic research, including but not limited to: Approximation Algorithms; Combinatorial Optimization; Compu- tional Biology; Computational Geometry; Databases and Information Retrieval; Graph and Network Algorithms; Machine Learning; Number Theory and Computer Algebra; On-line Algorithms; Pattern Matching and Data Compression; Symbolic Computation.