In Gene Regulatory Sequences and Human Disease, the Editor will introduce the different technological advances that led to this breakthrough. In addition, several examples will be provided of nucleotide variants in noncoding sequences that have been shown to be associated with various human diseases.

Historical fiction that speculates on how, US Naval rigid airships could have played a part in the war in the Pacific during World War II, if they had continued to evolve after 1935.

Vertebrate Skeletal Development, Volume 133, the latest release in the Current Topics in Developmental Biology series, presents interesting chapters on a variety of topics, with this edition focusing on Craniofacial skeletal development, Regulatory mechanism of jawbone and tooth development, Development of the axial skeleton and intervertebral discs, Stem and progenitor cells in skeletal development, Origin, functioning and morphogenetic activity of limb synovial joint, ECM signaling in cartilage development and endochondral ossification, Sox genes in skeletal development, Wnt-Signaling in Skeletal Development, Gas signaling in skeletal development and diseases, FGF signaling in skeletal development, Bone morphogenetic growth factors in bone development, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on Vertebrate Skeletal Development

Petri Nets were introduced in the doctoral dissertation by K.A. Petri, titled "Kommunikation mit Automaten" and published in 1962 by University of Bonn. Petri Nets are graphical (the intuitive graphical modeling language) and mathematical (advanced formal analysis method) tool. The concurrence of performed actions is the natural phenomenon due to which Petri Nets are perceived as mathematical tool for modeling concurrent systems. The main idea of this theory was modified by many researchers according to their needs, owing to the unusual "flexibility" of this theory. The present monograph focuses on Petri Nets applications in two main areas: manufacturing (section 1) and computer science (section 2). These two areas have still huge influence on our lives and our world. The theory of Petri Nets is still developing: some directions of investigations are presented in section 3. And at the end there is section 4 including some infesting facts concerning application of Petri Nets in the public area: the analysis and control of public bicycle sharing systems. The monograph shows the results of research works performed with use of Petri Nets in science centers all over the world.

Within six months of the devastating attack on Pearl Harbor, the U.S. Navy had checked the Japanese military advance in the Pacific to the extent that the United States could return to its original "Defeat Germany First" strategy. That the Navy was able to accomplish this feat with only six fleet aircraft carriers and little more than 1,000 combat aircraft was not sheer luck but the culmination of more than two decades of determined preparation. This thorough study, with detailed drawings and photographs, explains and illustrates the trial and error process which went into developing the aircraft, airships and ships of the interwar period. The critical factors that shaped Naval Aviation after World War I--naval treaties, fleet tactics, government programs, leadership and organization, as well as the emergence of Marine Corps and Coast Guard aviation--are discussed in depth.

In this third volume of The Quantum Theory of Fields, available for the first time in paperback, Nobel Laureate Steven Weinberg continues his masterly exposition of quantum field theory. This volume presents a self-contained, up-to-date and comprehensive introduction to supersymmetry, a highly active area of theoretical physics. The text introduces and explains a broad range of topics, including supersymmetric algebras, supersymmetric field theories, extended supersymmetry, supergraphs, non-perturbative results, theories of supersymmetry in higher dimensions, and supergravity. A thorough review is given of the phenomenological implications of supersymmetry, including theories of both gauge and gravitationally-mediated supersymmetry breaking. Also provided is an introduction to mathematical techniques, based on holomorphy and duality, that have proved so fruitful in recent developments. This book contains much material not found in other books on supersymmetry, including previously unpublished results. Exercises are included.

Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today’s clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. Covers today’s key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.