The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.

This textbook serves as a modern introduction to vascular biomechanics and provides the comprehensive overview of the entire vascular system that is needed to run successful vascular biomechanics simulations. It aims to provide the reader with a holistic analysis of the vascular system towards its biomechanical description and includes numerous fully through-calculated examples. Various topics covered include vascular system descriptions, vascular exchange, blood vessel mechanics, vessel tissue characterization, blood flow mechanics, and vascular tissue growth and remodeling. This textbook is ideally suited for students and researchers studying and working in classical and computational vascular biomechanics. The book could also be of interest to developers of vascular devices and experts working with the regulatory approval of biomedical simulations. Follows the principle of “learning by doing” and provides numerous fully through-calculated examples for active learning, immediate recall, and self-examination; Provides a holistic understanding of vascular functioning and the integration of information from different disciplines to enable students to use sophisticated numerical methods to simulate the response of the vascular system; Includes several case studies that integrate the presented material. Case studies address problems, such as the biomechanical rupture risk assessment of Abdominal Aortic Aneurysms, Finite Element analysis of structural and blood flow problems, the computation of wall stress and wall shear stress in the aorta.

This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.

"Modeling has provided not only answers to questions related to normal or pathological function but also predicted multiple adaptations of the total and individual dynamic structures that are included in cardiovascular research. The original idea of this book was to produce a textbook to be used for the course 'Modeling in Biomechanics and Mechanobiology', which is oriented to Artificial Organs and Tissue Engineering at Buenos Aires University, Argentina. This book brings together the challenges and experiences of academic scientists, leading engineers, industry researchers and students to enable them to analyse results of all aspects of biomechanics and biomedical engineering. It also provides a springboard to discuss the practical challenges and to propose solutions on this complex subject." -- Prové de l'editor.

This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.

This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.

Cowin (New York Center for Biomedical Engineering) and Humphrey (biomedical engineering, Texas A&M U.) present seven papers that discuss current research and future directions. Topics concern tissues within the cardiovascular system (arteries, the heart, and biaxial testing of planar tissues such as heart valves). Themes include an emphasis on data on the underlying microstructure, especially collagen; the consideration of the fact that both arteries and the heart contain muscle and that there is, therefore, a need to quantify both the active and passive response; constitutive relations for active behavior; and the growth and remodeling of cardiovascular tissues. Of interest to cardiovascular and biomechanics soft tissue researchers, and bioengineers. Annotation copyrighted by Book News, Inc., Portland, OR.

This book covers many aspects of human musculoskeletal biomechanics. As the title represents, aspects of forces, motion, kinetics, kinematics, deformation, stress, and strain are examined for a range of topics such as human muscles, skeleton, and vascular biomechanics independently or in the presence of devices. Topics range from image processing to interpret range of motion and/or diseases, to subject specific temporomandibular joint, spinal units, braces to control scoliosis, hand functions, spine anthropometric analyses along with finite element analyses. Therefore, this book will be valuable to students at introductory level to researchers at MS and PhD level searching for science of specific muscle/vascular to skeletal biomechanics. This book will be an ideal text to keep for graduate students in biomedical engineering since it is available for free, students may want to make use of this opportunity. Those that are interested to participate in the future edition of this book, on the same topic, as a contributor please feel free to contact the author.

This textbook is based on the author's one-semester course for advanced undergraduates and beginning graduate students in the area of biosolid/biofluid mechanics and biomaterials. Coverge includes an introduction to cardiovascular physiology and chapters on the rheology of blood, mechanics of blood vessels, steady and unsteady flow models, measurements in circulation, prosthetic vascular implants, cardiac imaging, myocardial mechanics, and ventricular assist devices and total artificial hearts. Annotation copyrighted by Book News, Inc., Portland, OR

Traditionally, applications of biomechanics will model system-level aspects of the human body. As a result, the majority of technological progress to date appears in system-level device development. More recently, biomechanical initiatives are investigating biological sub-systems such as tissues, cells, and molecules. Fueled by advances in experime