This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

A revolutionary and empowering paradigm in treating addiction based on groundbreaking new science. For decades addiction has been viewed and treated as a social and behavioral illness, afflicting people of "weak" character and "bad" moral fiber. However, recent breakthroughs in genetic technology have enabled doctors, for the first time, to correctly diagnose the disease and prove that addiction is an inherited, neuro-chemical disease originating in brain chemistry, determined by genetics, and triggered by stress. In their groundbreaking The Addiction Solution, David Kipper, MD, and Steven Whitney distill these exciting findings into a guide for the millions of adults who want to be free from the cycle of addiction, and for their loved ones who want to better understand it and to help. It draws on composite case histories to illustrate how the innovative Personal Recovery Program works by customizing treatment for a diverse group of addicts abusing a wide variety of different substances—from the first day of treatment to its successful resolution. The result is a complete guide to a world made brand-new by this enormous paradigm shift in the treatment of addiction.

Delivers an EMDR model that can expand access to urgently needed mental health services while maintaining affordability This innovative handbook is the first to present EMDR Group Therapy as a pragmatic approach to trauma care that enables practitioners to scale up mental health services while ensuring cost and time efficiency. It delivers step-by-step guidance—supported by real-life case examples—for practicing this safe, effective, and culturally adaptable modality in a wide range of situations and conditions. EMDR group protocols are applicable to inpatient and outpatient settings, strangers experiencing similar or different events, families, and a wide range of ages. The book explores how and why EMDR group protocols are applicable to disaster response, addictions, schools, medical challenges, grief, families, refugees, victims of sexual violence, emergency responders and more. The text describes the theoretical underpinnings and practical applications of EMDR Group Therapy, comparing nine group protocols through the lens of the eight phases of EMDR therapy and early intervention principles. It emphasizes the concept of task sharing, allowing nonspecialist facilitators to deliver low-intensity EMDR treatment options effectively. To promote in-depth understanding, chapters provide Learning Objectives, Learned Through Experience boxes, Case Examples focusing on a variety of specific groups and problems, Discussion Questions to reinforce knowledge, and unique Pocket Guides refining protocols and derived techniques in a clear snapshot. A full Glossary of terms is also provided at the end of the book. Key Features: The first book to disseminate the principles and applications of Group EMDR Therapy Delivers the knowledge of 36 contributing EMDR experts and researchers from 11 countries Follows the eight phases of standard EMDR protocol Offers a window into EMDR practice with a broad variety of specific groups and topics Detailed cultural competence checklist for practitioners to provide care with respect for diversity Includes multiple Case Examples, Learning Objectives, Learned Through Experience boxes, figures and charts, and much more Provides Pocket Guides for a clear, easy-to-follow snapshot of group EMDR protocols

This volume reviews the latest information about the treatment and prevention of major mental disorders that emerge during adolescence. It should be a primary resource for both clinicians and researchers, with special attention to gaps in our knowledge.

This text offers insights into the complex and disturbing questions of drug abuse by examining the range of factors that affect vulnerability, focusing specifically on factors and patterns associated with the transition from drug use to drug abuse.

Drug abuse and addiction are common in clinical practice. Often they interfere with patient treatment or require an alternative approach. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment is a major contribution to the literature, a gold standard title offering a comprehensive range of topics for those who care for patients with addiction, conduct research in this area, or simply have an interest in the field. Offering state-of-the-art information for all those working with drug abusing or addicted patients, or for those interested in this topic from other research perspectives, the volume is a first of its kind book -- rich, comprehensive, yet focused, addressing the needs of the very active theoretical, basic, and clinical research in the field. Comprised of 46 chapters organized in four sections and developed by the leading international experts, Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment covers virtually every core, as well as contemporary, topic on addiction, from the established theories to the most modern research and development in the field. Enhancing the educational value of the volume, every chapter includes an abstract and two boxes summarizing learning objectives and directions for future research. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment discusses the topic in a authoritative, systematic manner and is an indispensable reference for all clinicians and researchers interested in this rapidly changing field.

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. - A comprehensive reference on the effects of drug addiction on the human nervous system - Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs - Includes foundational science chapters on the biology of addiction - Details challenges in diagnosis and treatment options