The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. Unfolding the Biopolymer Landscape provides a unique account of “biopolymeric interventions” inherent to biotechnological applications, soft tissue engineering, ophthalmic drug delivery, biotextiles, environmentally responsive systems, neurotherapeutics, and emulsions-based formulations for food and pharmaceutical applications. Chapters in this volume also cover biomedical applications and implications of cationic polymers, collagen-based substrates, multifunctional polymers, shape memory biopolymers, hybrid semisynthetic biomaterials, microbial exopolysaccharides, biomaterials mimicking the extracellular microenvironment, derivatized polysaccharides, and metallic biomaterials. Each chapter is distinctly written by experts in the respective fields and emphasis is given on the mechanistic profile of the performance of biopolymers and biomedical applications. This book provides both basic and advanced biopolymer information for scientific experts and early career researchers in the field of drug delivery, tissue engineering, nanomedicine, food technology, peptide science, biomaterial design, and nutrition. This volume provides a unique account of “biopolymeric interventions” inherent to biotechnological applications, soft tissue engineering, ophthalmic drug delivery, biotextiles, environmentally responsive systems, neurotherapeutics, and emulsions-based formulations for food and pharmaceutical applications.

This book covers pharmaceutical residue dispersion in the aquatic environment and its toxic effect on living organisms. It discusses conventional and advanced remediation technologies such as the use of biomaterials for the sequestration of contaminants, nanotechnology, and phytoremediation. The book includes topics such as the removal of pharmaceutical and personal care product residues from water bodies, green chemistry, and legal regimens for pharmaceuticals in the aquatic environment. It also covers the application of modified biochar in pharmaceutical removal. FEATURES Explores the management of the environment through green chemistry Describes phytoremediation technology for decontamination of pharmaceutical-laden water and wastewater Covers the detection methods and quantification of pharmaceutical residues in various contaminated sources Discusses ecotoxicological aspects and risk assessment of pharmaceuticals in the aquatic environment Reviews degradation and treatment technologies including nanotechnology, biomaterials, and biochar This book is meant for pharmaceutical, toxicology, and environmental science industry experts and researchers.

This book is a comprehensive guide to bioconversion approaches based on microorganisms and enzymes for the valorization of underused wastes of diverse categories to produce new products. Optimized conditions for microbial and enzymatic valorization are discussed, along with related biotechnological considerations, environmental considerations, bioprocess development, obstacles, and future outlooks. Biofuels, bioenergy, and other platform chemicals are only some of the products that can be produced through this book's explanation of the microbiological processes involved in the bioconversion and valorization of wastes.

3D Printing and Microfluidics in Dermatology provides a thorough exploration and applications of three-dimensional (3D) printing and microfluidics within the field of dermatology. It investigates various methods utilized in these fields, such as 3D bioprinting, nano-transporters, microscopic fabrication, and device development. The book not only examines practical applications but also delves into the design principles crucial for implementing these techniques using specific materials tailored to their intended purposes. Additionally, it addresses ethical concerns and regulatory considerations pertinent to these evolving technologies. Key highlights include the following: A detailed insight into the utilization of 3D printing and microfluidic technologies for treating skin disorders. Exploration of design concepts necessary for effective implementation, considering the unique properties of materials involved. Coverage of diverse methodologies, ranging from 3D bioprinting to nano-transporters, microscopic fabrication, and device engineering. In-depth discussion on ethical considerations vital for the sustainable development of the industry. Investigation into advancements in material development, device design, fabrication techniques, and performance evaluation through preclinical and clinical studies. This book targets graduate students and researchers in fields such as 3D printing, dermatology, drug delivery, bioengineering, and pharmaceutical sciences.

This book examines the commercial role of various microbial polysaccharides and recent advances in their production. Offering an overview of the physiological role, biosynthetic pathways and regulatory mechanisms, it also explores the current challenges regarding bioprocessing for the production of polysaccharides.

Until the late 20th century, computational studies of biomolecules and nanomaterials had considered the two subjects separately. A thorough presentation of state-of-the-art simulations for studying the nanoscale behavior of materials, Simulations in Nanobiotechnology discusses computational simulations of biomolecules and nanomaterials together. Th

Information on our detailed genetic code is increasing at a dramatic pace. We need to understand how that is translated into the three-dimensional structure of proteins in order to make use of the information. Progress in this field is hampered by the lack of precise force fields and of efficient codes for finding equilibrium configurations of heteropolymers. However, there has been rapid advance in recent years, and this volume discusses that.

Biopolymer-Based Formulations: Biomedical and Food Applications presents the latest advances in the synthesis and characterization of advanced biopolymeric formulations and their state-of-the-art applications across biomedicine and food science. Sections cover the fundamentals, applications, future trends, environmental, ethical and medical considerations, and biopolymeric architectures that are organized in nano, micro and macro scales. The final section of the book focuses on novel applications and recent developments. This book is an essential resource for researchers, scientists and advanced students in biopolymer science, polymer science, polymer chemistry, polymer composites, plastics engineering, biomaterials, materials science, biomedical engineering, and more. It will also be of interest to R&D professionals, scientists and engineers across the plastics, food, biomedical and pharmaceutical industries. - Provides in-depth coverage of methods for the characterization of the physical properties of biopolymeric architectures - Supports a range of novel applications, including scaffolds, implant coatings, drug delivery, and nutraceutical encapsulation systems - Includes the use of experimental data and mathematical modeling, thus enabling the reader to analyze and compare the properties of different polymeric gels

This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design. X-ray crystallographic structures in combination with enzyme kinetic testing provide information on the interaction of CAs and their inhibitors, knowledge which is crucial for rational drug design. CAs are zinc carrying enzymes that catalyse the reversible interconversion of carbon dioxide and bicarbonate and are involved in numerous cellular processes. They are therefore a common target for drugs. The suppression of CA activities through inhibitory compounds has found application for example in diuretics and in glaucoma therapy. In this book methods used to determine binding thermodynamics of inhibitory compounds (Isothermal titration calorimetry, Fluorescent thermal shift assay/differential scanning fluorimetry and others) will be compared in detail. Also types and chemical synthesis of CA inhibitors, the use of antibodies against CAs as well as inhibitor application in animals are discussed.

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource