Myosins, actin-dependent molecular motors, are best known for their involvement in muscle contraction. However, besides classical (conventional) myosins, there is a vast number of other myosin motors that structurally and functionally do not resemble muscle myosins and therefore are termed as unconventional myosins. Since discovery in 1973 of the first unconventional myosin, myosin I, in Acanthamoeba castellanii by Thomas D. Pollard and Edward D. Korn, it has been shown that unconventional myosins form a large family, members of which are involved in a plethora of cellular functions, including those associated with intracellular trafficking and cell migration. However, despite the intensive research still many questions persist about their specific role(s) in these processes.

MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.

The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

This highly authoritative volume highlights the remarkable superfamily of molecular motors called myosins, which are involved in such diverse cellular functions as muscle contraction, intracellular transport, cell migration and cell division. In a timely compilation of chapters written by leading research groups that have made key discoveries in the field, the current understanding of the molecular mechanisms and biological functions of these intriguing proteins is explored.

DIATOM GLIDING MOTILITY Moving photosynthetic organisms are still a great mystery for biologists and this book summarizes what is known and reports the current understanding and modeling of those complex processes. The book covers a broad range of work describing our current state of understanding on the topic, including: historic knowledge and misconceptions of motility; evolution of diatom motility; diatom ecology & physiology; cell biology and biochemistry of diatom motility, anatomy of motile diatoms; observations of diatom motile behavior; diatom competitive ability, unique forms of diatom motility as found in the genus Eunotia; and models of motility. This is the first book attempting to gather such information surrounding diatom motility into one volume focusing on this single topic. Readers will be able to gather both the current state of understanding on the potential mechanisms and ecological regulators of motility, as well as possible models and approaches used to help determine how diatoms accomplish such varied behaviors as diurnal movements, accumulation into areas of light, niche partitioning to increase species success. Given the fact that diatoms remain one of the most ecologically crucial cells in aquatic ecosystems, we hope that this volume will act as a springboard towards future research into diatom motility and even better resolution of some of the issues in motility. Audience Diatomists, phycologists, aquatic ecologists, cellular physiologists, environmental biologists, biophysicists, diatom nanotechnologists, algal ecologists, taxonomists.