This book intensively examines the efficacy of plant-derived products that have been used for over a thousand years by practitioners of so-called Traditional Chinese Medicine in the light of recent chemotherapeuticals. The chapters were written by renowned Chinese medical researchers and are supplemented by results obtained in German antiparasitic research projects. Parasites and emerging diseases are a major threat of our time, which is characterized by an enormous increase in the size of the human population and by an unbelievably rapid globalization that has led to the daily transport of millions of humans and containers with goods from one end of the earth to the other. Furthermore the slow but constant global warming offers new opportunities for many agents of diseases to become established in new areas. Therefore it is essential that we develop precautions in order to avoid epidemics or even pandemics in overcrowded megacities or at the large-scale farm animal confinements that are needed to secure a steady flow of food in the crowded regions of the world. Of course intensive research in the field of chemotherapy since 1900 has produced unbelievable breakthroughs in therapies for formerly untreatable and thus deadly diseases. However, a large number of untreatable diseases remain, as well as a constantly growing number of agents of disease that have developed resistances to standard chemical compounds. As such, it is not only worthwhile but also vital to consider the enormous amounts of information that have been obtained by human “high cultures” in the past. Examples from the past (like quinine) or present (like artemisinin, a modern antimalarial drug) show that plant extracts may hold tremendous potential in the fight against parasites and/or against vector-transmitted agents of diseases.

This book emphasizes past and current research efforts about principles of natural control of major parasites affecting humans, animals, and crops. Each chapter is a complete and integrated subject that presents a problem and confers on the safe alternatives to chemicals. This book discusses and updates information about three major topics of natural remedies. The first topic is represented in a chapter outlining important information on biological control of parasites, the second topic is represented in three chapters dealing with botanicals as promising antiparasitic agents, and the last four chapters deal with miscellaneous control strategies against parasites. This easily readable book is designed precisely for students as well as professors linked with the field of parasitic control. We enhanced words with breathing areas in the form of graphical abstracts, figures, photographs, and tables.

This volume provides cutting-edge research from malaria parasitology and records the success story of disease control in China. The country, which was certified malaria-free by the World Health Organization in 2021, looks back on 70 years of effort and fruitful combat history. Expert authors supply insights from Plasmodium morphology to the clinical picture of malaria, molecular and immunodiagnosis, as well as current treatment and resistance issues, making this book a valuable blueprint for further success stories. The present work makes a significant contribution to the Sustainable Development Goal (SDG) 3, Good Health and Well-Being, with the aim to end malaria epidemics by 2030. Practical details of malaria elimination tools and strategies are completed by chapters on artificial intelligence in diagnosis and also traditional Chinese medicines for therapy. All researchers involved in malaria control and elimination around the globe will benefit from the knowledge presented, including students, scientists, policy makers at various levels, and professionals in healthcare and antiparasitic drug discovery.

This book focuses on waterborne pathogens and significant diseases occurring along major rivers around the globe, including key examples like the Amazonas, Mekong River and Nile. Written by leading international experts, it offers unique insights into local riverine infection risks in times of global warming, and addressing these through advances in diagnosis, health management and the development of simple but effective control measures. It also sheds light on why former societies collapsed due to transmitted diseases during periods of climate change, droughts and floods, to help establish effective preventive measures for the future. The book appeals to a wide readership, from scientists in the field of parasitology, infectious diseases and epidemiology, to healthcare managers and general readers with an interest in pathogen spread along the largest rivers on earth. It particularly highlights past and current control mechanisms in times of global warming and assesses potential future health hazards.

Schistosomiasis Control, the latest edition in the Advances in Parasitology series first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. The 2014 impact factor is 6.226, with a thematic issue focus on Schistosomiasis Control. - Informs and updates on all the latest developments in the field of parasitology - Includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes - Contains contributions from leading authorities and industry experts

This book addresses various clinical and sub clinical applications of antioxidant nutraceuticals, with a primary focus on preventive use for general wellness, common ailments, and such chronic illnesses as cancer and neurological applications. This unique book captures the applications of natural antioxidants, which have been used for thousands of years in Traditional Chinese Medicine and Ayurvedic Medicine as well as modern nutraceuticals formulations. It covers antioxidant applications in clinical scenarios including the historical perspective, basic antioxidant properties and applications, anti-inflammatory properties, and antioxidant applications in a variety of clinical conditions.

Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The seventh volume of this series features these interesting reviews: - Nucleic acid and peptide aptamers as potential antiviral drugs - Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens - Bioactive substances as anti-infective strategies against clostridioides difficile - Anti-toxoplasma drug discovery and natural products: a brief overview - Development of antimalarial and antileishmanial drugs from amazonian biodiversity

Essentials of Chinese Materia Medica and Medical Formulas: New Century Traditional Chinese Medicine presents specific knowledge about the source, medicinal nature, action and application of more than 800 commonly-used Chinese materia medica, as well as the efficacy and application of more than 740 kinds of commonly-used Chinese medical formulas. Notably, all of the content is presented in table form, making the information easier to access, understand and apply. Each primary herbal medicine is introduced with color pictures, and each primary formula is presented with efficacy analysis pictures. The book provides readers with essential information on Chinese materia medica and formulas and how to use them accurately, including the most common Chinese materia medica used in clinics and in commonly used clinical formulas. This is an essential reference for traditional medical professionals and those interested in traditional Chinese medicine, including advanced undergraduate and postgraduate students. - Includes over 800 Chinese materia medica and 740 medical formulas with their essential information - Combines 514 color pictures of medicine material crude slices and 255 formulary efficacy analysis pictures - Organized with concise forms, facilitating understanding and memorization

Studies in Natural Products Chemistry, Volume 57, covers rapid developments in spectroscopic techniques and advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products in new drug development. The series also covers the synthesis of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Specific sections in this release cover broad-spectrum health protection of extra virgin olive oil compounds, synthesis of cardiac steroids and their role on heart failure and cancer, and more. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores

Offering an example for transnational cooperation and successful reduction of a neglected tropical disease, this volume shows how Chinese scientists and local physicians controlled schistosomiasis in Zanzibar. Over a four-year study, local medical specialists and the population of Zanzibar were taught how to diagnose the parasitosis caused by flukes (trematode worms) of the genus Schistosoma. Furthermore, methods to eliminate the disease and prevent new infections were established. The developed control system will avoid repeated increase of human schistosomiasis, which is still prevalent in the tropics and subtropics. Rural populations and poor communities lacking access to clean drinking water and adequate sanitation are most affected. This book is a blueprint of activities urgently needed to combat schistosomiasis in countries with low medical impact. The strategies outlined are particularly relevant to parasitologists and professionals in public health, physicians, medical personnel and also governmental, healthcare and pharmaceutical institutions.