From #1 international bestselling author Ami McKay comes The Virgin Cure, the story of a young girl abandoned and forced to fend for herself in the poverty and treachery of post-Civil War New York City. McKay, whose debut novel The Birth House made headlines around the world, returns with a resonant tale inspired by her own great-great-grandmother’s experiences as a pioneer of women’s medicine in nineteenth-century New York. One summer night in Lower Manhattan in 1871, twelve-year-old Moth is pulled from her bed and sold as a servant to a finely dressed woman. Knowing that her mother is so close while she is locked away in servitude, Moth bides her time until she can escape, only to find her old home deserted and her mother gone without a trace. Moth must struggle to survive alone in the murky world of the Bowery, a wild and lawless enclave filled with thieves, beggars, sideshow freaks, and prostitutes. She eventually meets Miss Everett, the proprietress of an "Infant School," a brothel that caters to gentlemen who pay dearly for "willing and clean" companions—desirable young virgins like Moth. She also finds friendship with Dr. Sadie, a female physician struggling against the powerful forces of injustice. The doctor hopes to protect Moth from falling prey to a terrible myth known as the "virgin cure"—the tragic belief that deflowering a "fresh maid" can cleanse the blood and heal men afflicted with syphilis—which has destroyed the lives of other Bowery girls. Ignored by society and unprotected by the law, Moth dreams of independence. But there's a high price to pay for freedom, and no one knows that better than a girl from Chrystie Street. In a powerful novel that recalls the evocative fiction Anita Shreve, Annie Proulx, and Joanne Harris, Ami McKay brings to light the story of early, forward-thinking social warriors, creating a narrative that readers will find inspiring, poignant, adventure-filled, and utterly unforgettable.

In this breathtaking debut novel, Ami McKay has created an unforgettable portrait of the struggles that women have faced to control their own bodies and to keep the best parts of tradition alive in the world of modern medicine. The Birth House is the story of Dora Rare—the first daughter in five generations of Rares. As apprentice to the outspoken Acadian midwife Miss Babineau, Dora learns to assist the women of an isolated Nova Scotian village through infertility, difficult labors, breech births, unwanted pregnancies, and even unfulfilling sex lives. During the turbulent World War I era, uncertainty and upheaval accompany the arrival of a brash new medical doctor and his promises of progress and fast, painless childbirth. Dora soon finds herself fighting to protect the rights of women as well as the wisdom that has been put into her care. A tale of tradition and science, matriarchy and paternalism, past and future, The Birth House is "a dazzling first novel." (Library Journal), and a story more timely than ever.

The beloved, bestselling author of The Birth House and The Virgin Cure is back with her most beguiling novel yet, luring us deep inside the lives of a trio of remarkable young women navigating the glitz and grotesqueries of Gilded-Age New York by any means possible, including witchcraft... The year is 1880. Two hundred years after the trials in Salem, Adelaide Thom (Moth from The Virgin Cure) has left her life in the sideshow to open a tea shop with another young woman who feels it's finally safe enough to describe herself as a witch: a former medical student and gardien de sorts (keeper of spells), Eleanor St. Clair. Together they cater to Manhattan's high society ladies, specializing in cures, palmistry and potions—and in guarding the secrets of their clients. All is well until one bright September afternoon, when an enchanting young woman named Beatrice Dunn arrives at their door seeking employment. Beatrice soon becomes indispensable as Eleanor's apprentice, but her new life with the witches is marred by strange occurrences. She sees things no one else can see. She hears voices no one else can hear. Objects appear out of thin air, as if gifts from the dead. Has she been touched by magic or is she simply losing her mind? Eleanor wants to tread lightly and respect the magic manifest in the girl, but Adelaide sees a business opportunity. Working with Dr. Quinn Brody, a talented alienist, she submits Beatrice to a series of tests to see if she truly can talk to spirits. Amidst the witches' tug-of-war over what's best for her, Beatrice disappears, leaving them to wonder whether it was by choice or by force. As Adelaide and Eleanor begin the desperate search for Beatrice, they're confronted by accusations and spectres from their own pasts. In a time when women were corseted, confined and committed for merely speaking their minds, were any of them safe?

“Compelling... [A] sure-bet read-alike for Stephanie Danler’s Sweetbitter.” --Booklist A MOST ANTICIPATED BOOK by BuzzFeed, Goodreads, Electric Lit, New York Post, LitHub, BookRiot, and Library Journal A fiercely relatable coming-of-age debut novel about an aspiring bartender at the perfect Brooklyn neighborhood bar Samantha definitely does not want to be a bartender. But after a breakup and breakdown in San Francisco, she decides to defer law school for a year to move to New York, crashing on her best friend’s couch. When she is offered a job at Joe’s Apothecary, a beloved neighborhood bar in Brooklyn, she tells herself it’s only temporary. As Sam learns more about bartending and gets to know the service industry lifers and loyal regulars at Joe’s, she is increasingly seduced by her new job. She finds acceptance in her tight-knit community and even begins a new relationship. But as the year draws to a close, destructive cycles from her past threaten to consume her again. Sam is increasingly pulled between the life she thought she wanted and the possibility of a different kind of future. How much is she willing to let go of to finally belong? Filled with cocktail recipes and bartending tips and tricks, this captivating, utterly original debut will quench your thirst.

A provocative social history examines the history of virginity and of noted virgins in Western culture, describing the unique fascination civilization has had for virginity from a social, political, economic, philosophical, medical, and legal standpoint. Reprint.

Beloved author Ami McKay is back, bringing us a magical follow-up in the tradition of Victorian winter tales to her mesmerizing bestseller, The Witches of New York. During the nights between Christmas and New Year's, the witches of New York--Adelaide Thom, Eleanor St. Clair and the youngest, Beatrice Dunn--gather before the fire to tell ghost stories and perform traditional Yuletide divinations. (Did you know that roasting chestnuts was once used to foretell one's fate?) As the witches roast chestnuts and melt lead to see their fate, a series of odd messengers land on their doorstep bearing invitations for a New Year's Eve masquerade hosted by a woman they've never met. Gossip, dreams and portents follow, leading the witches to question the woman's motives. Is she as benevolent as she seems or is she laying a trap? And so, as Gilded-Age New York prepares to ring in the new year, the witches don their finery and head for the ball, on the hunt for answers that might well be the end of them.

This is a compelling study of the origins and history of the disease. Following the continuity of the disease from its classical roots up, this study questions the nature of the disease and the relationship between illness and body image.

“Engrossing . . . beautifully written and carefully crafted . . . [a] work that explores the healing power of truth.”—The Boston Globe For seventeen years, a rural community in Kansas has faithfully tended the grave of an anonymous teenage girl christened the Virgin of Small Plains. And some claim that, perhaps owing to the girl’s intervention, strange miracles and unexplainable healings have occurred. Slowly, word of the legend spreads. But what really happened in that snow-covered field almost two decades ago, when the girl’s naked, frozen body was found? Why did young Mitch Newquist disappear the day after the shocking discovery, leaving behind his distraught girlfriend, Abby Reynolds, and their best friend, Rex Shellenberger? Now Mitch has returned to Small Plains, reigniting simmering tensions and awakening secrets. Never having resolved her feelings for Mitch, Abby is determined to uncover the startling truth about his departure. The three former friends must confront the ever-unfolding consequences of the night that forever changed their lives—and the life of their small town. Praise for The Virgin of Small Plains “Nancy Pickard . . . has evolved into a writer of substantial literary power. . . . [She] has fashioned a novel that accurately reflects the secrets and silences locked deep within the hearts of all small-town Midwesterners.”—The Denver Post “Tantalizing . . . Pickard writes with insight and compassion about an unresolved crime that continues to haunt a farming community.”—The New York Times Book Review “A class act . . . Pickard has a talent for adding depth to a story that conveys a sense of place and history.”—Orlando Sentinel “Crisply written, this new novel about loss of faith, trust, and innocence is utterly absorbing.”—Tucson Citizen

After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, this book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in World War I led to early anti-cancer agents and how the efforts to decode the human genome might lead to new approaches in drug design. Stockwell then turns to the seemingly incurable diseases we face today, such as Alzheimer's, many cancers, and others with no truly effective medicines, and details the cellular and molecular barriers thwarting scientists equipped with only the tools of traditional pharmaceutical research. Scientists such as Stockwell are now developing methods to combat these complexities technologies for constructing and testing millions of drug candidates, sophisticated computational modeling, and entirely new classes of drug molecules all with an eye toward solving the most profound mysteries of living systems and finding cures for intractable diseases. If successful, these methods will unlock a vast terrain of untapped drug targets that could lead to a bounty of breakthrough medicines. Offering a rare, behind-the-scenes look at this cutting-edge research, The Quest for the Cure tells a thrilling story of science, persistence, and the quest to develop a new generation of cures.