Drawing on strange and thought-provoking case studies, an eminent neurologist offers unprecedented insight into the evolution of the uniquely human brain.

This fascinating book reveals what we learn about human nature when the brain goes wrong. It looks at why the human brain is so unique and examines how it became so complex.

The brain remains a mystery to us. How can a three-pound mass of jelly that can fit in our palm imagine angels, contemplate the meaning of infinity, and even question its own place in the cosmos? Renowned neuroscientist Prof. V.S. Ramachandran takes us on a fascinating journey into the human brain by studying patients who exhibit bizarre symptoms and using them to understand the functions of a normal brain. Along the way he asks big questions: How did abstract thinking evolve? What is art? Why do we laugh? How are these hardwired into the neural mechanisms of the human brain, and why did they evolve? Brilliant, lucid, and utterly compelling, The Tell-Tale Brain is a path-breaking book from one of the leading neuroscientists.

Neuroscientist V.S. Ramachandran is internationally renowned for uncovering answers to the deep and quirky questions of human nature that few scientists have dared to address. His bold insights about the brain are matched only by the stunning simplicity of his experiments -- using such low-tech tools as cotton swabs, glasses of water and dime-store mirrors. In Phantoms in the Brain, Dr. Ramachandran recounts how his work with patients who have bizarre neurological disorders has shed new light on the deep architecture of the brain, and what these findings tell us about who we are, how we construct our body image, why we laugh or become depressed, why we may believe in God, how we make decisions, deceive ourselves and dream, perhaps even why we're so clever at philosophy, music and art. Some of his most notable cases: A woman paralyzed on the left side of her body who believes she is lifting a tray of drinks with both hands offers a unique opportunity to test Freud's theory of denial. A man who insists he is talking with God challenges us to ask: Could we be "wired" for religious experience? A woman who hallucinates cartoon characters illustrates how, in a sense, we are all hallucinating, all the time. Dr. Ramachandran's inspired medical detective work pushes the boundaries of medicine's last great frontier -- the human mind -- yielding new and provocative insights into the "big questions" about consciousness and the self.

Meet Edgar and Allan Poe -- twelve-year-old identical twins, the great-great-great-great-grandnephews of Edgar Allan Poe. They look and act so much alike that they're almost one mischievous, prank-playing boy in two bodies. When their beloved black cat, Roderick Usher, is kidnapped and transported to the Midwest, Edgar and Allan convince their guardians that it's time for a road trip. Along the way, mayhem and mystery ensue, as well as deeper questions: What is the boys' telepathic connection? Is Edgar Allan Poe himself reaching out to them from the Great Beyond? And why has a mad scientist been spying on the Poe family for years? With a mix of literary humor, mystery, a little quantum physics, and fun extras like fortune cookie messages, letters in code, license plate clues -- and playful illustrations thoughout -- this series opener is a perfect choice for smart, funny tweens who love the Time Warp Trio, Roald Dahl, and Lemony Snicket.

In Edgar Allan Poe's "The Tell-Tale Heart", the narrator tries to prove his sanity after murdering an elderly man because of his "vulture eye". His growing guilt leads him to hear the old man's heart beating under the floorboards, which drives him to confess the crime to the police.

"How can people come to believe that their poodle is an impostor? Or see colors in numbers? Francis Crick, co-discoverer of DNA, said of V. S. Ramachandran's first book, "The patients he describes are fascinating, and his experiments on them are both simple and ingenious." With his unique energy and style Ramachandran now shares his insights into the mind from such everyday human experiences as pain, sight, and the appreciation of beauty to the ultimate philosophical conundrums of consciousness."--BOOK JACKET.

Phineas Gage was truly a man with a hole in his head. Phineas, a railroad construction foreman, was blasting rock near Cavendish, Vermont, in 1848 when a thirteen-pound iron rod was shot through his brain. Miraculously, he survived to live another eleven years and become a textbook case in brain science. At the time, Phineas Gage seemed to completely recover from his accident. He could walk, talk, work, and travel, but he was changed. Gage "was no longer Gage," said his Vermont doctor, meaning that the old Phineas was dependable and well liked, and the new Phineas was crude and unpredictable. His case astonished doctors in his day and still fascinates doctors today. What happened and what didn't happen inside the brain of Phineas Gage will tell you a lot about how your brain works and how you act human.

Key concepts in neuroscience presented for the non-medical reader. A fresh take on contemporary brain science, this book presents neuroscience—the scientific study of brain, mind, and behavior—in easy-to-understand ways with a focus on concepts of interest to all science readers. Rigorous and detailed enough to use as a textbook in a university or community college class, it is at the same time meant for any and all readers, clinicians and non-clinicians alike, interested in learning about the foundations of contemporary brain science. From molecules and cells to mind and consciousness, the known and the mysterious are presented in the context of the history of modern biology and with an eye toward better appreciating the beauty and growing public presence of brain science.

Previously published in hardcover: New York: Free Press, 2012.