The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.

SHORTLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2022 THE TIMES SCIENCE BOOK OF THE YEAR A GUARDIAN BEST POLITICS BOOK OF THE YEAR A TOP 5 SUNDAY TIMES BESTSELLER *Revised and updated edition with new chapter reflecting on the impact of Covid-19 two years on, and what come next* Did the UK government really 'follow the science' throughout the Covid-19 pandemic, as it claims? As head of the Wellcome Trust, Jeremy Farrar was one of the first people in the world to hear about a mysterious new disease in China - and to learn it could readily spread between people. A member of the SAGE emergency committee, Farrar was a key figure in both the UK and the World Health Organization at the onset of the Covid-19 pandemic amid great uncertainty, fast-moving situations and missed opportunities. Spike is his widely acclaimed inside story. His account casts light on the UK government's claims to be 'following the science' and is informed not just by Farrar's views but by interviews with other top scientists and political figures.

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.

This career-spanning monograph is a visual celebration of Spike Lee's life and career to date. Featuring hundreds of never-before-seen photographs by David Lee, Spike's brother, this book includes behind-the-scenes, insider images that underscore his creative process, and his significant impact on the culture at large. Print run 15,000.

Intended for neurobiologists with an interest in mathematical analysis of neural data as well as the growing number of physicists and mathematicians interested in information processing by "real" nervous systems, Spikes provides a self-contained review of relevant concepts in information theory and statistical decision theory.

Human life and the human condition are changing rapidly, and are about to change even faster and more radically. Dazzling scientific breakthroughs are changing how long we live, where we live, how we dress, how we communicate, how we work and what work we do, and even how we think and imagine. Scientist Vernor Vinge proposed that humanity is approaching what he called the Singularity, what Broderick has renamed the Spike: that moment in human history when heretofore unimaginable changes -- artificial intelligence, immortality, and nanotechnology, just to name a few -- occur with such rapidity and number that the human race will be transformed -- or destroyed. This book of wonders and dangers brings together all the fascinating possibilities. Don't miss Broderick's new Tor novel, Transcension, also published in February, in which one of the futures described in The Spike is the setting for a diverting entertainment. Copyright © Libri GmbH. All rights reserved.

Join Jack Vargo as he explores a popular tool and weapon in Colonial North America in The Spike Tomahawk. This book discusses the origin, methods of manufacture, distribution and importance of a tool and weapon during the colonial period. Vargo's intention in writing this volume is to provide readers a comprehensive study of just one type of trade artifact, a small hatchet having a metal head with a cutting bit at one end and a pick or spike at the other, known by most as the "spiked axe" or "spike tomahawk".

A rare look at Spike Lee’s creative appropriation of the documentary film genre. In this groundbreaking book, Delphine Letort sheds light on a neglected part of Spike Lee’s filmmaking by offering a rare look at his creative engagement with the genre of documentary filmmaking. Ranging from history to sports and music, Lee has tackled a diversity of topics in such nonfiction films as 4 Little Girls, A Huey P. Newton Story, Jim Brown: All-American, and When the Levees Broke: A Requiem in Four Acts. Letort analyzes the narrative and aesthetic discourses that structure these films and calls attention to Lee’s technical skills and narrative-framing devices. Drawing on film and media studies, African American studies, and cultural theories, she examines the sociological value of Lee’s investigations into contemporary culture and also explores the ethics of his commitment to a genre characterized by its claim to truth. “The Spike Lee Brand makes a very important contribution to scholarly studies on the film-work of Spike Lee [and] places Lee in the pantheon of important social political documentarians such as Claude Lanzmann and Emile de Antonio.” — from the Foreword by Mark A. Reid

"Dogs bark at those with whom we are angry, show their teeth to those whom we hate, and hump themselves on those that we desire. In short they display that which we are not permitted to display by the rules of the veil that calls itself polite society." "The child can take two paths to creating the adult. The first is the path of Pygmalion. He carved from ivory a statue that he loved. He made offerings and sacrifices and his statue was granted life by Aphrodite. Was the statue granted life because Pygmalion's diligence and sculpting skill pleased his patron? Or was it the beauty of the statue that pleased her? No, it was the sacrifices. The child must sacrifice much before the gods allow him to become a fully living adult. Pygmalion's statue aged and died with him. The child is cruelly denied this experience. The child must also give up its own life for the adult to live. Sometimes one or both of its parents must do the same. The second path that the child may take is that of Hephaestus."