One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

The fundamental principles of the scientific method are essential for enhancing perspective, increasing productivity, and stimulating innovation. These principles include deductive and inductive logic, probability, parsimony and hypothesis testing, as well as science's presuppositions, limitations, ethics and bold claims of rationality and truth. The examples and case studies drawn upon in this book span the physical, biological and social sciences; include applications in agriculture, engineering and medicine; and also explore science's interrelationships with disciplines in the humanities such as philosophy and law. Informed by position papers on science from the American Association for the Advancement of Science, National Academy of Sciences and National Science Foundation, this book aligns with a distinctively mainstream vision of science. It is an ideal resource for anyone undertaking a systematic study of scientific method for the first time, from undergraduates to professionals in both the sciences and the humanities.

As the gateway to scientific thinking, an understanding of the scientific method is essential for success and productivity in science. This book is the first synthesis of the practice and the philosophy of the scientific method. It will enable scientists to be better scientists by offering them a deeper understanding of the underpinnings of the scientific method, thereby leading to more productive research and experimentation. It will also give scientists a more accurate perspective on the rationality of the scientific approach and its role in society. Beginning with a discussion of today's 'science wars' and science's presuppositions, the book then explores deductive and inductive logic, probability, statistics, and parsimony, and concludes with an examination of science's powers and limits, and a look at science education. Topics relevant to a variety of disciplines are treated, and clarifying figures, case studies, and chapter summaries enhance the pedagogy. This adeptly executed, comprehensive, yet pragmatic work yields a new synergy suitable for scientists and instructors, and graduate students and advanced undergraduates.

This book shows how science works, fails to work, or pretends to work, by looking at examples from such diverse fields as physics, biomedicine, psychology, and economics. Social science affects our lives every day through the predictions of experts and the rules and regulations they devise. Sciences like economics, sociology and health are subject to more ‘operating limitations’ than classical fields like physics or chemistry or biology. Yet, their methods and results must also be judged according to the same scientific standards. Every literate citizen should understand these standards and be able to tell the difference between good science and bad. Scientific Method enables readers to develop a critical, informed view of scientific practice by discussing concrete examples of how real scientists have approached the problems of their fields. It is ideal for students and professionals trying to make sense of the role of science in society, and of the meaning, value, and limitations of scientific methodology in the social sciences.

The surprising history of the scientific method—from an evolutionary account of thinking to a simple set of steps—and the rise of psychology in the nineteenth century. The idea of a single scientific method, shared across specialties and teachable to ten-year-olds, is just over a hundred years old. For centuries prior, science had meant a kind of knowledge, made from facts gathered through direct observation or deduced from first principles. But during the nineteenth century, science came to mean something else: a way of thinking. The Scientific Method tells the story of how this approach took hold in laboratories, the field, and eventually classrooms, where science was once taught as a natural process. Henry M. Cowles reveals the intertwined histories of evolution and experiment, from Charles Darwin’s theory of natural selection to John Dewey’s vision for science education. Darwin portrayed nature as akin to a man of science, experimenting through evolution, while his followers turned his theory onto the mind itself. Psychologists reimagined the scientific method as a problem-solving adaptation, a basic feature of cognition that had helped humans prosper. This was how Dewey and other educators taught science at the turn of the twentieth century—but their organic account was not to last. Soon, the scientific method was reimagined as a means of controlling nature, not a product of it. By shedding its roots in evolutionary theory, the scientific method came to seem far less natural, but far more powerful. This book reveals the origin of a fundamental modern concept. Once seen as a natural adaptation, the method soon became a symbol of science’s power over nature, a power that, until recently, has rarely been called into question.

This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.

A Summary of Scientific Method is a brief description of what makes science scientific. It is written in a direct, clear style that is accessible and informative for scientists and science students. It is intended to help science teachers explain how science works, highlighting strengths without ignoring limitations, and to help scientists articulate the process and standards of their work. The book demonstrates that there are several important requirements for being scientific, and the most fundamental of these is maintaining an extensive, interconnected, coherent network of ideas. Some components in the network are empirical, others are theoretical, and they support each other. Clarifying the structure of this web of knowledge explains the role of the commonly cited aspects of scientific method, things like hypotheses, theories, testing, evidence, and the like. A Summary of Scientific Method provides a clear, intuitive, and accurate model of scientific method.

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Researchers, historians, and philosophers of science have debated the nature of scientific research in education for more than 100 years. Recent enthusiasm for "evidence-based" policy and practice in educationâ€"now codified in the federal law that authorizes the bulk of elementary and secondary education programsâ€"have brought a new sense of urgency to understanding the ways in which the basic tenets of science manifest in the study of teaching, learning, and schooling. Scientific Research in Education describes the similarities and differences between scientific inquiry in education and scientific inquiry in other fields and disciplines and provides a number of examples to illustrate these ideas. Its main argument is that all scientific endeavors share a common set of principles, and that each fieldâ€"including education researchâ€"develops a specialization that accounts for the particulars of what is being studied. The book also provides suggestions for how the federal government can best support high-quality scientific research in education.