In order for today's organizations to achieve success, improvement must be generated from within. This book explains how organizations can develop effective improvement plans based upon their unique strengths and corporate objectives, and demonstrates how to most effectively manage or work within the four basic types of corporate cultures.

The pharmaceutical industry is currently operating under a business model that is not sustainable for the future. Given the high costs associated with drug development, there is a vital need to reform this process in order to provide safe and effective drugs while still securing a profit. Re-Engineering Clinical Trials evaluates the trends and challenges associated with the current drug development process and presents solutions that integrate the use of modern communication technologies, innovations and novel enrichment designs. This book focuses on the need to simplify drug development and offers you well-established methodologies and best practices based on real-world experiences from expert authors across industry and academia. Written for all those involved in clinical research, development and clinical trial design, this book provides a unique and valuable resource for streamlining the process, containing costs and increasing drug safety and effectiveness. - Highlights the latest paradigm-shifts and innovation advances in clinical research - Offers easy-to-find best practice sections, lists of current literature and resources for further reading and useful solutions to day-to-day problems in current drug development - Discusses important topics such as safety profiling, data mining, site monitoring, change management, increasing development costs, key performance indicators and much more

The most successful business book of the last decade, Reengineering the Corporation is the pioneering work on the most important topic in business today: achieving dramatic performance improvements. This book leads readers through the radical redesign of a company's processes, organization, and culture to achieve a quantum leap in performance. Michael Hammer and James Champy have updated and revised their milestone work for the New Economy they helped to create -- promising to help corporations save hundreds of millions of dollars more, raise their customer satisfaction still higher, and grow ever more nimble in the years to come.

This title is of value to businesses from all sectors which are considering their re-engineering and restructuring options, as well as those that are reviewing both their approach to international expansion, and whether there are other ways to penetrate domestic markets which their typical expansion model does not allow them to address.This first edition of Alternative Corporate Re-engineering will be of great assistance to corporations and their counsel, providing valuable insights and guidance to these complicated processes

Every day, new warnings emerge about artificial intelligence rebelling against us. All the while, a more immediate dilemma flies under the radar. Have forces been unleashed that are thrusting humanity down an ill-advised path, one that's increasingly making us behave like simple machines? In this wide-reaching, interdisciplinary book, Brett Frischmann and Evan Selinger examine what's happening to our lives as society embraces big data, predictive analytics, and smart environments. They explain how the goal of designing programmable worlds goes hand in hand with engineering predictable and programmable people. Detailing new frameworks, provocative case studies, and mind-blowing thought experiments, Frischmann and Selinger reveal hidden connections between fitness trackers, electronic contracts, social media platforms, robotic companions, fake news, autonomous cars, and more. This powerful analysis should be read by anyone interested in understanding exactly how technology threatens the future of our society, and what we can do now to build something better.

Holonic networks give businesses the agility to rapidly change product and service capabilities to meet rapidly changing market demands, offering the following advantages: leverage, speed, flexibility, fast growth and high profits, sustainable customers, reduced capital requirement, and quick failure recognition. In this book, the authors describe how holonic networks and the virtual companies within them have been implemented in businesses as diverse as Ford, Hewlett Packard, Benetton and R Griggs, the company that makes Doc Marten shoes. Beyond Business Process Reengineering provides a thought provoking and practical examination of business today. For everyone in business being pulled through competition, technological change and their own reengineering efforts, it provides a new and radical alternative to downsizing, restructuring, cost reduction and strategic repositioning.

Diagnosing and Changing Organizational Culture provides a framework, a sense-making tool, a set of systematic steps, and a methodology for helping managers and their organizations carefully analyze and alter their fundamental culture. Authors, Cameron and Quinn focus on the methods and mechanisms that are available to help managers and change agents transform the most fundamental elements of their organizations. The authors also provide instruments to help individuals guide the change process at the most basic level—culture. Diagnosing and Changing Organizational Culture offers a systematic strategy for internal or external change agents to facilitate foundational change that in turn makes it possible to support and supplement other kinds of change initiatives.

Business process reengineering is arguably the management paradigm of the decade. No other paradigm for organizational innovation and improvement has achieved a stronger presence and impact in corporate boardrooms around the world. In recent years reengineering has also moved away from the hype into real-world application, and there is now a vast pool of techniques and experience ready to be tapped by organizational-change advocates.This book provides an international showcase of reengineering in action, with contributions from more than forty experts spanning five continents. Besides prescriptions of concepts and tools, it presents case studies of public sector as well as private sector reengineering experience, and visions of the future of reengineering practice.

In today's manufacturing environment, the integration of commercial, production, maintenance, and engineering functions is a common and crucial goal. In this timely volume, Richard G. Lamb presents a new standard within the enterprise and plant design management. Lamb shows readers how to advance the plant's role in enterprise business performance and leadership by most cost effectively achieving the mechanical availability necessary to perform in the face of current events, business cycles, and industry trends. Performance is from the designed and managed reliability and maintainability of its equipment.