A practical guide to perioperative cognitive disorders, the most common complications of anesthesia and surgery in older people.

Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. - Quick and easy reference for understanding problems in neuroanesthesia - Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients - Includes useful section with clinical case studies of complications in neuroanesthesia

This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important clinical challenges encountered in day-to-day practice in the OR, the PACU, and the ICU and is designed as a problem-solving tool for all members of the perioperative medicine team: trainees and faculty in anesthesiology, neurosurgery, and critical care; nurses; nurse anesthetists; and physician’s assistants. • Encompasses clinical continuum from neurosurgical pre-op to critical care – plus anesthesia in neuroradiology • Adult and pediatric care • Structured algorithmic approach supports clinical decision-making • Succinct presentation of clinically relevant basic science • End-of-chapter summaries, with suggestions for further reading • Collaborative approach and multidisciplinary nature of perioperative medicine emphasized • Extensive summary tables • Portable and formatted for quick retrieval of information • Ideal for use in the OR, the PACU, and the ICU

This unique and richly illustrated volume presents the state of the art in the comprehensive management of major neurosurgical diseases in the elderly (aged 65 and over). It explores all of the common neurosurgical pathologies affecting elderly patients, and emphasizes the paramount importance of tailored management strategies for quality of life. It highlights updated techniques for anaesthesia and critical care, as well as minimally invasive neurosurgical methods intended for this specific group of patients. Radiosurgery treatment is also discussed, in particular for brain tumours. In western societies, the proportion of elderly citizens has nearly reached 20%, and shows no signs of slowing down. The management of neurosurgical conditions in this particular population requires specific multidisciplinary strategies. To address this situation, a team of internationally respected contributors accurately describe degenerative and traumatic spinal diseases, which account for the majority of admissions among the elderly, as well as brain tumours and intracranial haemorrhages, aspects that are raising new ethical issues. The book mainly addresses the needs of neurosurgeons and geriatric neurologists, but also neuro-oncologists and neuro-anaesthesists working with elderly patients, as well as students in these disciplines.

Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Geriatric anesthesia is a rapidly growing and evolving field and this is the major revision of a classic anesthesia reference. The last few years have seen significant advancements and important new modalities for addressing the needs of an aging population. The editors of this second edition are uniquely situated to put together a text highlighting both essential knowledge and recent breakthroughs of importance to all who work with the elderly. This edition easily maintains the high standard for quality scholarship and useful material set by the first.

The third edition of Psychiatric Care of the Medical Patient brings a classic reference text into the twenty-first century. It combines critical scholarship with the voice of expert clinicians who work at the interface of psychiatry with medical specialties. It is meant to be read for pleasure as well as consulted as a reference. The editors have worked with the authors to bring a consistent perspective to the book - one that sees the medical psychiatrist as an agent for bringing a more comprehensive perspective to medical care. Even seasoned and knowledgeable practitioners will find much that is new to them in this book. The volume covers topics in depth that other books in the field may not cover at all, such as the use of herbal and nutritional therapies for medical-psychiatric symptoms and syndromes, and the choice of questionnaires to supplement history-taking. It looks at old topics in a new way: The chapter on the physical examination applies psychometric considerations to the Babinski sign, describes the method and application of quantitative bedside olfactory testing, and discusses smartphone apps to improve the sensitivity of the examination. Psychiatric Care of the Medical Patient, 3rd Edition provides concepts and information to facilitate the dialogue between psychiatrists and general medical specialists - minimizing psychiatric jargon and speaking in the common language of caring and curious physicians.

This new edition of one of the premier references for geriatric nurses in hospital, long-term, and community settings delivers current guidelines, real-life case studies, and evidence-based protocols developed by master educators and practitioners. With a focus on improving quality of care, cost-effectiveness, and outcome, the fifth edition is updated to provide the most current information about care of common clinical conditions and issues in older patients. Several new expert contributors present current guidelines about hip fractures, frailty, perioperative and postoperative care, palliative care, and senior-friendly emergency departments. Additionally, chapters have been reorganized to enhance logical flow of content and easy information retrieval. Protocols, systematically tested by more than 300 participating NICHE (Nurses Improving Care for Health system Elders) hospitals‚ are organized in a consistent format and include an overview, evidence-based assessment and intervention strategies, and an illustrative case study with discussion. Additionally, protocols are embedded within chapter text, providing the context and detailed evidence for each. Chapter objectives, annotated references,and evidence ratings for each protocol are provided along with resources for additional study. New to the Fifth Edition: Reorganized to enhance logical flow of information and ease of use Updated and revised Includes new contributions from expert educators and practitioners Provides new chapters on perioperative and postoperative care, general surgical care, care of hip fracture, palliative care, and the senior-friendly emergency department Key Features: Includes PowerPoints and a test bank for instructors Delivers evidence-based, current guidelines and protocols for care of common clinical conditions in the older person Illustrates the application of clinical protocols to real-life practice through case studies and discussion Edited by nationally known geriatric leaders who are endorsed by the Hartford Institute for Geriatric Nursing and NICHE Written for nursing students, nurse leaders, and practitioners at all levels, including those in specialty roles

Long regarded as the undisputed leading text of its kind, Miller's Basics of Anesthesia provides comprehensive yet concise coverage of both basic science and clinical topics in anesthesiology. Under the experienced editorial leadership of Dr. Manuel C. Pardo, Jr., the 8th Edition has been meticulously updated to reflect the latest advances in practice and important aspects of contemporary anesthesia care, including pathophysiology, pharmacology, regional anesthesia, anesthetic management, and special problems and patient groups. It remains the first learning resource of choice for anesthesia providers, including anesthesia residents and fellows, medical students, and student registered nurse anesthetists, and is also a valuable review tool for practitioners undergoing maintenance of certification or recertification. - Features a reader-friendly format with color-coded section tabs, easy-to-read chapters, and a concise writing style, along with color patterns in every chapter for quick navigation. - Contains new chapters on Clinician Well-Being, Perioperative Point-of-Care Ultrasound, Environmental Impact of Anesthetics, and Perioperative Medicine. - Covers key topics such as anesthesia neurotoxicity, palliative care, sleep medicine, trauma, and much more. - Includes high-quality images that offer a detailed visual understanding of complex topics, while numerous figures and tables condense material for easier retention and review. - Shares the knowledge and experience of renowned anesthesia expert Dr. Manuel C. Pardo, Jr. and a team of more than 80 global contributing authors. - Serves both as an initial learning resource and a useful tool for solidifying the essential "must know" information and reviewing core knowledge for maintenance of certification. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.