"England may with justice claim to be the native land of transfusion," wrote one European physician in 1877, acknowledging Great Britain’s crucial role in developing and promoting human-to-human transfusion as treatment for life-threatening blood loss. As news of this revolutionary medical technique spread from professional publications to popular journals and newspapers, the operation invaded the Victorian imagination. Transfusion is the first extended study of this intersection between medical and literary history. It examines the medical discourse that surrounded the real nineteenth-century practice of transfusion, which focused on women suffering from uterine hemorrhage, alongside literary works that exploited the operation’s sentimental, satirical, sensational, and gothic potentials. In the eighteenth century, the term "transfusion" was used to figure aesthetic and religious inspiration as well as erotic and romantic commingling—associations that persisted into the nineteenth century and informed attitudes toward the medical practice of blood transfer and the cultural conception of sympathetic exchange. Exploring transfusion’s role in canonical works such as Wells’s The Island of Dr. Moreau and Stoker’s Dracula, as well as a surprising array of lesser-known short stories and novels, Kibbie demonstrates the tangled, mutually informing relationship between science and culture. This innovative study traces the creation of a new fluid economy between persons, one that could be seen to forge new forms of intimacy between donors and recipients or to threaten the very idea of personal identity.

This volume presents a selection from the American and British fiction of the nineteenth century which was evolving into what we now know as science fiction. Taking Frankenstein as its formative work, it assembles stories and excerpts from narratives exploring the complex impact of new technologies like the telegraph and later the cinema, or new scientific practices like mesmerism (hypnotism) and microscopy. The selected authors range from those famous within the realist tradition like George Eliot and Mark Twain to scientists like the physician Silas Weir Mitchell and the inventor Thomas Edison. They repeatedly destabilize their narratives so that some come to resemble scientific records and frequently leave their endings unresolved, encouraging the reader to speculate about their subjects, which include extensions to the senses, new inventions, and challenges to individual autonomy. Many focus on experiments but might combine scientific enquiry with the supernatural, producing hybrid narratives as a result which are difficult to classify.

William Godwin’s Mandeville was described as his best novel by Percy Shelley, who sent a copy to Lord Byron, and it was immediately recognized by its other admirers as a work of unique power. Written one year after the battle of Waterloo and set in an earlier revolutionary period between the execution of Charles I and the Restoration, Mandeville is a novel of psychological warfare. The narrative begins with Mandeville’s rescue from the traumatic aftermath of the Ulster Rebellion of 1641 and proceeds through his early education by a fanatical Presbyterian minister to his persecution at Winchester school, his constant (and not unjustified) paranoia, and his confinement in an asylum. Mandeville’s final, desperate attempt to prevent his sister’s marriage to his enemy ends with his disfiguration, which also defaces endings based on settlement or reconciliation. The novel’s events have many resonances with Godwin’s own period. The historical appendices offer contemporary reviews, including Shelley’s letter to Godwin praising Mandeville, material explaining the novel’s complex historical background, and contemporary writings on war, madness, and trauma.