The Mechanism of Tumor Evolution and Microenvironmental Changes of Genitourinary Oncology in Clinical Diagnosis and Treatment,volume II

The Mechanism of Tumor Evolution and Microenvironmental Changes of Genitourinary Oncology in Clinical Diagnosis and Treatment,volume II
Author :
Publisher : Frontiers Media SA
Total Pages : 104
Release :
ISBN-10 : 9782832551790
ISBN-13 : 2832551793
Rating : 4/5 (90 Downloads)

Synopsis The Mechanism of Tumor Evolution and Microenvironmental Changes of Genitourinary Oncology in Clinical Diagnosis and Treatment,volume II by : Hailiang Zhang

Tumor microenvironment (TME) is a bidirectional, dynamic and intricate network of interactions between tumor cells and mesenchymal tissue cells. Therefore, an in-depth study in TME is of great significance for clarifying tumor biology and molecular mechanisms during tumorigenesis and progression. The genitourinary tumors mainly include relatively high-incidence malignant prostate cancer, kidney cancer and bladder cancer, and relatively rare adrenocortical cancer, penile cancer, and so on. There are various complex intercellular communications in genitourinary tumor microenvironment. Many cells reprogram their metabolic pathways to adapt to an acidic hypoxic environment, providing energy support for growth and metastasis of genitourinary tumors. The heterogeneity of genitourinary TME makes tumor progression quite different between individuals. Therefore, it is necessary to analyze the interaction between tumor cells and stromal components, the key components that exert anti-tumor immunity (such as cytotoxic T lymphocytes, TAM, MDSC, etc.) and other genitourinary tumor microenvironment characterizations

Diagnosis and Treatment of Genitourinary Malignancies

Diagnosis and Treatment of Genitourinary Malignancies
Author :
Publisher : Springer Science & Business Media
Total Pages : 397
Release :
ISBN-10 : 9781461563433
ISBN-13 : 1461563437
Rating : 4/5 (33 Downloads)

Synopsis Diagnosis and Treatment of Genitourinary Malignancies by : Kenneth J. Pienta

The field of genito-urinary oncology is rapidly evolving at virtually every level. Significant advances have been made in our understanding of the molecular and cellular events which contribute to the generation of GU malignancies. At the same time, similar advances have been made in the clinical arena which have improved the diagnosis and treatment of urologic cancers. This volume attempts to summarize those advances which most impact us as clinicians, and has been divided into three sections. Section One, `Diagnostic advances: the use of molecular medicine in the diagnosis and prognosis of GU malignancies', details how epidemiologic studies and new molecular techniques are impacting our ability to diagnose and treat GU tumors. Section Two, `Surgical and radiation advances', details the recent major advances in the treatment of organ-confined cancers. Section Three, `Medical advances', addresses major issues in the treatment of metastatic disease. This volume will serve as a compendium of the advances, both at the basic science and clinical levels, which are currently impacting practicing oncologists and urologists.

Oncology of CNS Tumors

Oncology of CNS Tumors
Author :
Publisher : Springer Science & Business Media
Total Pages : 776
Release :
ISBN-10 : 9783642028748
ISBN-13 : 3642028748
Rating : 4/5 (48 Downloads)

Synopsis Oncology of CNS Tumors by : Jörg-Christian Tonn

Knowledge about the etiology and diagnosis as well as treatment concepts of neu- oncologic diseases is rapidly growing. This turnover of knowledge makes it dif? cult for the physician engaged in the treatment to keep up to date with current therapies. This book sets out to close the gap and pursues several innovative concepts. As a comprehensive text on neuro-oncology, its chapters are interconnected, but at the same time some chapters or subdivisions are so thoroughly assembled that the whole volume gives the impression of several books combined into one. Neuropathology is treated in an extensive and clearly structured section. The int- ested reader ? nds for each tumor entity the latest well-referenced consensus rega- ing histologic and molecular pathology. Through this “book-in-the-book” concept, information on neuropathology is readily at hand in a concise form and without ov- loading the single chapters. Pediatric neuro-oncology differs in many entities from tumors in adult patients; also, certain tumors of the CNS are typically or mainly found only in the child. Therefore, pediatric neuro-oncology was granted its own, book-like section. Tumor entities that are treated differently in children and adults are included both in the pediatric neuro-oncology section and in the general section. Entities that typically occur only in the child and adolescent are found in the pediatric section in order to avoid redundancies.

Clinical Oncology

Clinical Oncology
Author :
Publisher :
Total Pages : 0
Release :
ISBN-10 : 044307545X
ISBN-13 : 9780443075452
Rating : 4/5 (5X Downloads)

Synopsis Clinical Oncology by : Martin D. Abeloff

A must-have reference, this new edition provides practical information on treatment guidelines, details of diagnosis and therapy, and personal recommendations on patient management from experts in the field. Consistently formatted chapters allow for a user-friendly presentation for quick access of key information by the practicing clinician. Completely updated, this new edition includes all of the latest developments in treatment strategies of medical, surgical and radiation oncologists.

Accuracy Requirements and Uncertainties in Radiotherapy

Accuracy Requirements and Uncertainties in Radiotherapy
Author :
Publisher :
Total Pages : 297
Release :
ISBN-10 : 9201008155
ISBN-13 : 9789201008152
Rating : 4/5 (55 Downloads)

Synopsis Accuracy Requirements and Uncertainties in Radiotherapy by : International Atomic Energy Agency

Accuracy requirements in radiation oncology have been defined in multiple publications; however, these have been based on differing radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have been reduced and more detailed patient outcome data are available. No comprehensive literature on accuracy and uncertainties in radiotherapy has been published so far. The IAEA has therefore developed a new international consensus document on accuracy requirements and uncertainties in radiation therapy, to promote safer and more effective patient treatments. This publication addresses accuracy and uncertainty issues related to the vast majority of radiotherapy departments including both external beam radiotherapy and brachytherapy. It covers clinical, radiobiological, dosimetric, technical and physical aspects.

Pediatric Head and Neck Tumors

Pediatric Head and Neck Tumors
Author :
Publisher : Springer Science & Business Media
Total Pages : 380
Release :
ISBN-10 : 9781461487555
ISBN-13 : 1461487552
Rating : 4/5 (55 Downloads)

Synopsis Pediatric Head and Neck Tumors by : Reza Rahbar

The pediatric head and neck cancer patient necessitates a multidisciplinary team of specialists to provide an optimal continuum of care. This A-Z guide provides practical, in-depth information for all medical professionals involved in the evaluation and treatment of these patients. Written in an easy to follow format, each entry contains illustrative figures to aid in pathological and radiographical diagnosis, as well as structured discussion of evaluation and multimodality management. The alphabetical layout eliminates redundancy and allows the busy physician to quickly locate relevant information. Pediatric Head and Neck Tumors is ideal for young physicians as well as attending physicians seeking to expand their knowledgebase to the various subspecialties involved in the multidisciplinary care of their patients.

Surgical Techniques in Rectal Cancer

Surgical Techniques in Rectal Cancer
Author :
Publisher : Springer
Total Pages : 597
Release :
ISBN-10 : 9784431555797
ISBN-13 : 443155579X
Rating : 4/5 (97 Downloads)

Synopsis Surgical Techniques in Rectal Cancer by : Giovanni Dapri

This book describes the various procedures, including surgery through the abdominal wall, through a transanal access or by the union of both, using an open, laparoscopic, or robotic approach. Worldwide pioneers for each technique are invited as authors and portray in step-by-step detail about each procedure. Of the 32 chapters, 23 are dedicated only for the surgical procedures. Each chapter is enriched by numerous figures, which complement the text, permitting the understanding of each surgical technique from its beginning until the last step. Eight additional chapters are dedicated to the clinical and anatomical aspects of rectal cancer. In the last decade there has been an impressive evolution in the treatment of patients with rectal cancer, with a focus not only on the preservation of a cancer-free life, but the quality of that life. This book has been written to be useful for everyone involved in rectal cancer management. From internists, gastroenterologists, endoscopists, oncologists, radiotherapists and radiologists involved in the treatment of rectal cancer during their daily practice, to surgeons specialized in colorectal surgery, to junior faculty to trainees, all interested in new and innovative techniques.

50 Studies Every Urologist Should Know

50 Studies Every Urologist Should Know
Author :
Publisher : Oxford University Press
Total Pages : 352
Release :
ISBN-10 : 9780190655365
ISBN-13 : 0190655364
Rating : 4/5 (65 Downloads)

Synopsis 50 Studies Every Urologist Should Know by : Philipp Dahm

50 Studies Every Urologist Should Know presents key studies that have shaped the practice of urology. Selected using a rigorous methodology, the studies cover topics including reflux disease in paediatric urology, management of male erectile dysfunction and lower urinary tract symptoms, female urology and stone disease, the various forms of genitourinary cancer, and more. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for healthcare professionals in urology, as well as anyone who wants to learn more about the data behind clinical practice.

Modification of Radiation Response

Modification of Radiation Response
Author :
Publisher : Springer Science & Business Media
Total Pages : 308
Release :
ISBN-10 : 3540422315
ISBN-13 : 9783540422310
Rating : 4/5 (15 Downloads)

Synopsis Modification of Radiation Response by : Carsten Nieder

This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.