This volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and neurodegeneration), fundamental neuroscience and basic subterranean biology. In 2013, Science magazine named the naked mole-rat as the Vertebrate of the Year. This was partly due to research carried out documenting its extreme longevity, negligible senescence, and prolonged maintenance of cancer free, good health well into old age as well as seminal work on mechanisms involved in these processes, pain and hypoxia resistance. In addition to this research focus on longevity and chronic diseases such as cancer and cardiovascular disease, the naked mole-rat has also made a substantial contribution to the fields of ecophysiology, neuroscience and behavior. With international contributions, this book provides a valuable text for zoological students, behavioral scientists and biomedical researchers.

This volume brings together more than a decade of information collected in the field and lab on the naked mole-rat (Heterocephalus glaber), a northeast African mammal unique for its physical characteristics and eusociality. Nearly blind and virtually hairless, naked mole-rats inhabit large subterranean colonies in which only one female and her one to three mates conceive offspring, while the young from previous litters maintain and defend the group as do workers in colonies of the social insects. In this first major treatise on naked mole-rats an international group of researchers covers such topics as the evolution of eusociality, phylogeny and systematics of the rodent family Bathyergidae, population and behavioral ecology and genetics of naked mole-rats in the field, vocal and nonvocal behaviors, social organization and divisions of labor within colonies, and climatic, social, and physiological factors affecting growth, reproduction, and reproductive suppression. In addition to the editors, the contributors are D. H. Abbott, M. W. Allard, N. C. Bennett, R. A. Brett, S. H. Braude, B. Crespi, S. V. Edwards, C. G. Faulkes, L. M. George, R. L. Honeycutt, E. A. Lacey, C. E. Liddell, E. McDaid, K. Nelson, K. M. Noonan, J. O'Riain, J. W. Pepper, H. K. Reeve, and D. A. Schlitter. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Wilbur, a naked mole rat who likes to wear clothes, is forced to go before the wise community elder, who surprises the other naked mole rats with his pronouncement.

"Examines the adaptations and life of naked mole-rats"--

If you could have any animal's front teeth, whose would you choose? What If You Had Animal Teeth!? takes children on a fun, informative, and imaginative journey as they explore what it would be like if their own front teeth were replaced by those of a different animal. Featuring a dozen animals (beaver, great white shark, narwhal, elephant, rattlesnake, naked mole rat, hippopotamus, crocodile, and more), this book explores how different teeth are especially adapted for an animal's survival. At the end of the book, children will discover why their own teeth are just right for them. And they'll also get a friendly reminder to take good care of their teeth, because they're the only teeth they'll ever have. Each spread features a photograph of the animal using its specialized teeth on the left and a humorous illustrated image of a child using that animal's teeth on the right.

*FINALIST FOR THE 2020 GENERAL NONFICTION MINNESOTA BOOK AWARDS* Interested in the origins of the species? Consider the Platypus uses pets such as dogs and cats as well as animal outliers like the axolotl and naked mole rat to wittily tackle mind-bending concepts about how evolution, biology, and genetics work. Consider the Platypus explores the history and features of more than 50 animals to provide insight into our current understanding of evolution. Using Darwin's theory as a springboard, Maggie Ryan Sandford details scientists' initial understanding of the development of creatures and how that has expanded in the wake of genetic sequencing, including the: Peppered Moth, which changed color based on the amount of soot in the London air; California Two-Spotted Octopus, which has the amazing ability to alter its DNA/RNA not over generations but during its lifetime; miniscule tardigrade, which is so hearty it can withstand radiation, lack of water and oxygen, and temperatures as low as -328°F and as high 304 °F; and, of course, the platypus, which has so many disparate features, from a duck's bill to venomous spur to mammary patches, that scientists originally thought it was a hoax. Surprising, witty, and impeccably researched, Sandford describes each animal's significant features and how these have adapted to its environment, such as the zebra finch's beak shape, which was observed by Charles Darwin and is a cornerstone of his Theory of Evolution. With scientifically accurate but charming art by Rodica Prato, Consider the Platypus showcases species as diverse as the sloth, honey bee, cow, brown kiwi, and lungfish, to name a few, to tackle intimidating concepts is a accessible way.

From acclaimed journalist Bill Gifford comes a roaring journey into the world of anti-aging science in search of answers to a universal obsession: what can be done about getting old? Spring Chicken: Stay Young Forever (or Die Trying) Spring Chicken is a full-throttle, high-energy ride through the latest research, popular mythology, and ancient wisdom on mankind's oldest obsession: How can we live longer? And better? In his funny, self-deprecating voice, veteran reporter Bill Gifford takes readers on a fascinating journey through the science of aging, from the obvious signs like wrinkles and baldness right down into the innermost workings of cells. We visit cutting-edge labs where scientists are working to "hack" the aging process, like purging "senescent" cells from mice to reverse the effects of aging. He'll reveal why some people live past 100 without even trying, what has happened with resveratrol, the "red wine pill" that made headlines a few years ago, how your fat tissue is trying to kill you, and how it's possible to unlock longevity-promoting pathways that are programmed into our very genes. Gifford separates the wheat from the chaff as he exposes hoaxes and scams foisted upon an aging society, and arms readers with the best possible advice on what to do, what not to do, and what life-changing treatments may be right around the corner. An intoxicating mixture of deep reporting, fascinating science, and prescriptive takeaway, Spring Chicken will reveal the extraordinary breakthroughs that may yet bring us eternal youth, while exposing dangerous deceptions that prey on the innocent and ignorant.

This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research.

Molecular Biology of the Hepatitis B Virus presents a comprehensive account of the various molecular aspects of the life cycle of the hepatitis B virus (HBV). Topics covered include the animal model systems, sequence data on the hepadnavirus genomes, the transcripts coded for the biral genome and sequence elements involved in regulating their expression, hepadnavirus replication, and analysis of the various HBV gene products and their role in virion synthesis and assembly. Other important features of the book include its discussions of the consequences of long term exposure to hepadnavirus infection and its association with hepatocellular carcinoma, the use of recombinant technologies in the generation of second generation vaccines, and the utilization of recombinant technologies to analyze an immune mediated disease. Researchers studying hepadnaviruses will find a wealth of information in this essential reference volume.

Can Kit’s super-weird superpower save her world? Twelve-year-old kit (with a small k) likes shopping at the flea market with her best friend, Clem, roller-skating, climbing to the roof to look at the stars, and volunteering at an animal shelter. Until suddenly she has a really big, really strange secret that makes life more complicated than she’s prepared for: Sometimes, without warning, she turns into a tiny naked mole rat. It first happened as kit watched Clem fall and get hurt during a performance with her acrobatic-troupe family on TV. Since then, the transformations keep coming. Kit can’t tell Clem, because Clem hasn’t been herself after the accident. She’s mad and gloomy and keeping a secret of her own: the real reason she fell. Months later, kit and Clem still haven’t figured out how to deal with all the ways they have changed—both inside and out. Somehow, kit has to save the day. But she’s no hero, and turning into a naked mole rat isn’t a superpower. Or is it?