This volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and neurodegeneration), fundamental neuroscience and basic subterranean biology. In 2013, Science magazine named the naked mole-rat as the Vertebrate of the Year. This was partly due to research carried out documenting its extreme longevity, negligible senescence, and prolonged maintenance of cancer free, good health well into old age as well as seminal work on mechanisms involved in these processes, pain and hypoxia resistance. In addition to this research focus on longevity and chronic diseases such as cancer and cardiovascular disease, the naked mole-rat has also made a substantial contribution to the fields of ecophysiology, neuroscience and behavior. With international contributions, this book provides a valuable text for zoological students, behavioral scientists and biomedical researchers.

This volume brings together more than a decade of information collected in the field and lab on the naked mole-rat (Heterocephalus glaber), a northeast African mammal unique for its physical characteristics and eusociality. Nearly blind and virtually hairless, naked mole-rats inhabit large subterranean colonies in which only one female and her one to three mates conceive offspring, while the young from previous litters maintain and defend the group as do workers in colonies of the social insects. In this first major treatise on naked mole-rats an international group of researchers covers such topics as the evolution of eusociality, phylogeny and systematics of the rodent family Bathyergidae, population and behavioral ecology and genetics of naked mole-rats in the field, vocal and nonvocal behaviors, social organization and divisions of labor within colonies, and climatic, social, and physiological factors affecting growth, reproduction, and reproductive suppression. In addition to the editors, the contributors are D. H. Abbott, M. W. Allard, N. C. Bennett, R. A. Brett, S. H. Braude, B. Crespi, S. V. Edwards, C. G. Faulkes, L. M. George, R. L. Honeycutt, E. A. Lacey, C. E. Liddell, E. McDaid, K. Nelson, K. M. Noonan, J. O'Riain, J. W. Pepper, H. K. Reeve, and D. A. Schlitter. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Wilbur, a naked mole rat who likes to wear clothes, is forced to go before the wise community elder, who surprises the other naked mole rats with his pronouncement.

"Examines the adaptations and life of naked mole-rats"--

The Nude Mouse in Experimental and Clinical Research presents the state of knowledge regarding the nude mouse and its applications to different branches of scientific research. The research studies featured in this book emphasize the academic status of a broad range of subjects and techniques of nude mouse research. The text consists of 21 chapters, each discussing an important aspect of nude mouse research. Some chapters discuss the biological aspect such as physiology, genes, and breeding and mass production of the mouse. A number of the chapters also discuss the general observations of the mouse like histopathological observations and their background. The applications of the nude mouse to human tumor and cancer cell research are likewise given emphasis. This book will be of valuable importance to both students and researchers in the fields of medicine, biology, and pathology.

Do you love rodents? Did you know that there's a rodent with no fur? Read this book to learn about the naked mole rat's amazing adaptations.

The Naked Mole Rat is exactly what it sounds like - it's a species of rat belonging to the order of rodents, and it is called "naked" because it has very little hair, leaving its skin totally exposed. This animal is also called by other names, such as Sand Puppy and Desert Mole Rat. If you've seen newly born puppies, then you know that they somewhat look like a mouse or a rat, which is why it's called a Sand Puppy. The sand part refers to the type of place they prefer to live in. Its other name, Desert Mole Rat, is easier to understand. Of course, they can be found in deserts, and the very nature of the animal called a mole is that they live underground - just like Naked Mole Rats. This animal is therefore very interesting because of its looks and its overall characteristics. Wouldn't you like to know it better? Read on and you will find out how amazing Naked Mole Rats are.

The understanding of pig genetics and genomics has advanced significantly in recent years, creating fresh insights into biological processes. This comprehensive reference work discusses pig genetics and its integration with livestock management and production technology to improve performance. Fully updated throughout to reflect advances in the subject, this new edition also includes new information on genetic aspects of domestication, colour variation, genomics and pig breeds, with contributions from international experts active in the field.

The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

*FINALIST FOR THE 2020 GENERAL NONFICTION MINNESOTA BOOK AWARDS* Interested in the origins of the species? Consider the Platypus uses pets such as dogs and cats as well as animal outliers like the axolotl and naked mole rat to wittily tackle mind-bending concepts about how evolution, biology, and genetics work. Consider the Platypus explores the history and features of more than 50 animals to provide insight into our current understanding of evolution. Using Darwin's theory as a springboard, Maggie Ryan Sandford details scientists' initial understanding of the development of creatures and how that has expanded in the wake of genetic sequencing, including the: Peppered Moth, which changed color based on the amount of soot in the London air; California Two-Spotted Octopus, which has the amazing ability to alter its DNA/RNA not over generations but during its lifetime; miniscule tardigrade, which is so hearty it can withstand radiation, lack of water and oxygen, and temperatures as low as -328°F and as high 304 °F; and, of course, the platypus, which has so many disparate features, from a duck's bill to venomous spur to mammary patches, that scientists originally thought it was a hoax. Surprising, witty, and impeccably researched, Sandford describes each animal's significant features and how these have adapted to its environment, such as the zebra finch's beak shape, which was observed by Charles Darwin and is a cornerstone of his Theory of Evolution. With scientifically accurate but charming art by Rodica Prato, Consider the Platypus showcases species as diverse as the sloth, honey bee, cow, brown kiwi, and lungfish, to name a few, to tackle intimidating concepts is a accessible way.