Flies (Dipteria) have had an important role in deepening scientists'understanding of modern biology and evolution. The study of flies has figured prominently in major advances in the fields of molecular evolution, physiology, genetics, phylogenetics, and ecology over the last century. This volume, with contributions from top scientists and scholars in the field, brings together diverse aspects of research and will be essential reading for entomologists and fly researchers.

It is not often that one has the opportunity to send a public birthday greet ing to a friend and colleague of many years, and to congratulate him on having reached the age of reason. In fact it happens only once, and comes then as a surprise. Surely it was only a few years ago that we sat together at an International Genetics Congress in Ithaca, and only yesterday that we became members of the same department. The eighth floor of Schermerhorn Hall had a north end where the flies were and a south end furnished with mice, and in between, a seminar room and laboratory. There the distances were short and the doors open and the coffee pot busy. But it now appears that yesterday has fallen thirty years behind and that we have grown up. I find it interesting and appropriate that Dobzhansky's lifetime spans the period of maturation of the fields to which this volume is devoted. This is true in a chronological sense for his birth occurred in the same year, 1900, in which modern genetics began. The rediscovery of Mendel's princi ples and the interpretation of the nature of heredity and variation to which this event led were necessary prerequisites to the development of evolution ary biology as presented in this collection of essays.

Understanding how a multicellular animal develops from a single cell (the fertilized egg) poses one of the greatest challenges in biology today. Development from egg to adult involves the sequential expression of virtually the whole of an organism's genetic instructions both in the mother as she lays down developmental cues in the egg, and in the embryo itself. Most of our present information on the role of genes in development comes from the invertebrate fruit fly, Drosophila. The two authors of this text (amongst the foremost authorities in the world) follow the developmental process from fertilization through the primitive structural development of the body plan of the fly after cleavage into the differentiation of the variety of tissues, organs and body parts that together define the fly. The developmental processes are fully explained throughout the text in the modern language of molecular biology and genetics. This text represents the vital synthesis of the subject that many have been waiting for and it will enable many specific courses in developmental biology and molecular genetics to focus on it. It will appeali to 2nd and 3rd year students in these disciplines as well as in biochemistry, neurobiology and zoology. It will also have widespread appeal among researchers. Authored by one of the foremost authorities in the world. A unique synthesis of the developmental cycle of Drosophila - our major source of information on the role of genes in development. Designed to provide the basis of new courses in developmental biology and molecular genetics at senior undergraduate level. A lucid explanation in the modern language of the science.

Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the species Drosophila melanogaster, the great workhorse of genetics. Michael Rose and his colleagues have been able to double the lifespan of these insects, and improved their health in numerous respects as well. The study of these flies with postponed aging is one of the best means we have of understanding, and ultimately achieving, the postponement of aging in humans. As such, the carefully presented detail of this book will be of value to research devoted to the understanding and control of aging.Methuselah Flies: ? is a tightly edited distillation of twenty years of work by many scientists? contains the original publications regarding the longer-lived fruit flies? offers commentaries on each of the topics covered ? new, short essays that put the individual research papers in a wider context? gives full access to the original data ? captures the scientific significance of postponed aging for a wide academic audienc

A comparison of the genetic circuits of Homo sapiens and Drosophila reveals the evidence for deep homology.

Flies (Dipteria) have had an important role in deepening scientists'understanding of modern biology and evolution. The study of flies has figured prominently in major advances in the fields of molecular evolution, physiology, genetics, phylogenetics, and ecology over the last century. This volume, with contributions from top scientists and scholars in the field, brings together diverse aspects of research and will be essential reading for entomologists and fly researchers.

"Tells the story of how the marvelous discoveries of molecular and developmental biology are transforming our understanding of who we are and where we came from. Jacob scrutinizes the place of the scientist in society". -- Jacket.

How do new animal and plant species come about? How quickly does it happen? And what are species anyway? Schilthuizen, reputed scientist and journalist, launches into the debate that has baffled biologists ever since Darwin, with tremendous energy and wit. The whole subject leaps to life andits significance for understanding biodiversity comes clear. This is a fascinating read that will appeal equally to the lay reader and to students getting to grips with the fundementals of a complex subject.

Written for academic researchers and graduate students in entomology, this is the first comprehensive analysis of Sciomyzid flies. Sciomyzid flies are important as prime candidates for the biological control of snails and slugs that help transmit diseases such as schistosomiasis or are important agricultural pests. They also serve as a paradigm for the study of the evolution of feeding behavior in predatory insects. Starting with analyses of malacophagy in general and then in Diptera specifically, all important aspects of the Sciomyzidae are discussed, including behavior, ecology, life cycles, morphology, and identification. New behavioral and morphological classifications and hypotheses are proposed on the basis of unpublished information and a complete analysis of the extensive literature. Also included are keys to adults, larvae and puparia and a checklist of world species, with information on geographical range and the location of type specimens. The accompanying DVD includes Clifford O. Berg's classic film on the biology of Sciomyzidae and biological control of snails.

"One of the most productive of all laboratory animals, Drosophila has been a key tool in genetics research for nearly a century. At the center of Drosophila culture from 1910 to 1940 was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges, who, by inbreeding fruit flies, created a model laboratory creature - the 'standard' fly. By examining the material culture and working customs of Morgan's research group, [the author] brings to light essential features of the practice of experimental science. [This book] takes a broad view of experimental work, ranging from how the fly was introducted into the laboratory and how it was physically redesigned for use in genetic mapping, to how the 'Drosophilists' organized an international network for exchanging fly stocks that spread their practices around the world"--Back cover.