This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Giuseppe Bagliani, Roberto De Ponti, and Fabio Leonelli is dedicated to The Complex World of Cardiac Pre-Excitation: towards Precision Electrocardiology. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Anatomy of the AV junction, Pre-excitation, Algorithms to identify accessory pathways location on 12-lead ECG, Pathophysiology of accessory pathways-mediated arrhythmias, Arrhythmias with by-stander accessory pathways, Arrhythmias involving unusual accessory pathways, Sudden cardiac death in patients with ventricular pre-excitation, Clinical approach to symptomatic and asymptomatic patients with ventricular pre-excitation, Methodology of accessory pathway ablation, Ablation of accessory pathways with unusual anatomic location, Ablation of accessory pathways with uncommon electrophysiologic properties, and Ablation in pediatric patients and in association with congenital heart disease.

This book presents the features of Wolff-Parkinson-White and other preexcitation syndromes with detailed discussion of the management and treatment of these patients. Catheter ablation has become a curative first-line treatment for circus movement tachycardias involving accessory pathway conduction. However, diagnostic and interventional challenges may be associated with anatomically and electrophysiologically complex single accessory pathway conduction, multiple accessory pathways, accessory pathways with other coexistent tachycardias, including atrioventricular nodal reentrant tachycardia and atrial tachycardias, and accessory pathways with coexistent congenital heart disease. The complexity involved requires a thorough theoretical and practical knowledge for performing unequivocally conclusive/meaningful electrophysiological testing and successful catheter ablation. This book is based on the author’s personal long-term experience and contains over 700 illustrations of intracardiac recordings and fluoroscopic images, as well as clear and user-friendly descriptions of the electrophysiologic data, its analysis and interpretation. It therefore offers a comprehensive practical guide for mapping and catheter ablation. The systematic approach is also invaluable for accessory pathways coexistent with other arrhythmias or congenital heart diseases. Wolff-Parkinson-White and Other Preexcitation Syndromes presents the topic as a fascinating part of clinical cardiac electrophysiology and all types of corresponding accessory pathways, which are often associated with diagnostic and interventional challenges. It therefore provides an invaluable educational resource to further scientific and medical knowledge in the topic and will be essential reading for all electrocardiologists and any medical professional that manages these patients.

correction of such a reentry when he observed The W olff-Parkinson-White (WPW) syndrome, . . . in a favourable experiment, the vigorous the most common variety of preexcitation, has for some time held a fascination for those circulating wave and its instantaneous arrest by interested in clinical electrophysiology because section of the ring is a sight not easily forgotten. it seems to represent a naturally occurring event which, if adequately understood, would un Courageous is the only way to describe the mask answers to many fundamental questions first attempt to surgically interrupt an accessory concerning mechanisms and treatment of car pathway. The immensity of the feat speaks for diac arrhythmias. Thus, it has been described by itself: Open heart surgery was performed to Scherf and Neufeld [1] as the "Rosetta Stone" divide an invisible stream of electrons! This of electrocardiography. historic event was not anticipated. A fisherman The historic overview of the pre excitation from the coast of North Carolina presented to syndromes will be deferred to Dr. Burchell's Duke University Medical Center in 1968 with authoritative chapter, but a few highlights de refractory supraventricular tachycardia related serve emphasis here because they graphically to the WPW syndrome [2]. Attempts to control portray how elements of serendipity, courage, the tachycardia medically failed. Dr. Andrew and luck played important roles in the unfold Wallace (then Director of the Coronary Care Unit) had recently returned from the NIH ing of the mysteries of preexcitation.

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Luigi Padeletti and Giuseppe Bagliani, will cover the latest in Normal Electrophysiology, Substrates, and the Electrocardiographic Diagnosis of Cardiac Arrhythmias. Topics covered in this issue include History of Arrhythmias; P wave and arrhythmias originating in the atria; PQ interval and Junctional zone; QRS complex; Ventricular repolarization during arrhythmias; Classification and specific electrocardiographic pattern of Cardiac Arrhythmias; and Electrocardiographic practice of cardiac arrhythmias.

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Pramod Deshmukh and Kenneth A. Ellenbogen, will focus on His Bundle Pacing. Topics include, but are not limited to, Bundle of His – A contemporary reappraisal, Electrophysiology of bundle branch block, Pacing-induced cardiomyopathy, Tricuspid valve dysfunction caused by RV leads, His Bundle Pacing – concept to reality, How to perform HBP - Tools and techniques, Electro-anatomical atlas of HBP (LAO/RAO views & recorded Egms), Hemodynamics of His bundle pacing in comparison Apical & Septal pacing, HBP for cardiac resynchronization, Long-term results of HBP, Getting on the curve – learning HBP, HBP in conjunction with AV node ablation in AF, and Ongoing clinical trials and future developments.

This issue of Cardiac Electrophysiology Clinics examines electrocardiography of complex arrhythmias. Topics include concealed conduction, right and left atrial macroreentrant tachycardias, focal atrial fachycardias, AV nodal and AV reentrant tachycardia, wide complex tachycardias, ventricular tachycardia in CAD, ECG characteristics of outflow tract VT, fascicular tachycardias, VT in non-ischemic dilated cardiomyopathy, VT originating from unusual sites, incessant VT and VT storms, ECG characteristics of TdP, VT in ARVC, and ventricular arrhythmia in inherited channelopathies, arrrhythmias in complex congenital heart disease, AV conduction disease and block, electrocardiographic analysis of paced rhythms.

“Variants of Ventricular Preexcitation: Recognition and Treatment provides a unique opportunity for general cardiologists and electrophysiologists to find in one text the intricacies of recognizing and treating a group of disorders that has intrigued physicians for more than 100 years.” --from the Foreword by Mark E. Josephson, MD, Chief, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, USA Drs Sternick and Wellens combine their expertise in the diagnosis and treatment of cardiac arrhythmias to bring you this complete overview of decrementally conducting accessory pathways and their role in cardiac arrhythmias. This is the first book dedicated to these special types of accessory pathways, their recognition and management. By covering the uncommon varieties of ventricular preexcitation, this book supports you in improving patient care by: Helping you to identify decrementally conducting AV fibers- which comprise 3-5 % of all accessory AV pathways Explaining exactly what information can be obtained from the 12-lead ECG Showing how to identify and localize these pathways during an electrophysiologic study Detailing the proper treatment and how to treat these patients By explaining the fundamental pathophysiology as well as the diverse clinical presentation of arrhythmias, Drs Sternick and Wellens demystify the subject of the different variants of decrementally conducting accessory pathways leading to ventricular pre-excitation and their role in cardiac arrhythmias.

Debates and controversies about how to treat difficult problems or conditions abound in cardiac electrophysiology. This issue attempts to bring together a variety of controversial subjects and to present differing views on how to resolve these questions so clinicians will have a handy guide to the most current thinking about these difficult subjects.

The Clinical Cardiac Electrophysiology Handbook, Second Edition, is a concise presentation in outline format of the practical information needed to understand the subtleties of cardiac electrophysiology. The Handbook focuses on the “how-to” management of arrhythmias, along with an understanding of the “why.” “. . . a quick source for information in the EP lab or on the wards offering the ability to quickly review the essential components before a case or to reinforce new notions and practices encountered during a case.” — From the Preface -Fully illustrated with more than 250 figures and tables. -Equally valuable to the cardiology fellow on their electrophysiology rotation, or an EP fellow or technologist working in the EP lab. New and updated sections in the Second Edition: -Ablation energy and biophysics, including pulsed field ablation -AF ablation techniques adjunctive to pulmonary vein isolation -Alternatives to cardiac resynchronization therapy -His bundle pacing -Intracardiac echocardiography -Left atrial appendage occlusion

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Jason Bradfield and Kalyanam Shivkumar, is dedicated to Epicardial Interventions in Electrophysiology. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Anatomy of the Pericardial Space, Techniques for Percutaneous Access, Peri-operative Imaging to Guide Epicardial Mapping and Ablation, Epicardial Ablation of Idiopathic Ventricular Tachycardia, Epicardial Ablation of Ischemic Ventricular Tachycardia, Epicardial Ablation of Non-ischemic Ventricular Tachycardia, Epicardial Ablation of Arrhythmogenic Right Ventricular Cardiomyopathy, Epicardial Ablation of Ventricular Arrhythmia secondary to Brugada Syndrome, Epicardial Ablation of Supraventricular Tachycardia, Epicardial Ablation of Atrial Fibrillation, Hybrid Surgical Epicardial Ablation, Epicardial Ablation via the Arterial and Venous System, Epicardial Ablation Biophysics and novel Radiofrequency Energy Delivery Techniques, Epicardial Ablation Complications, and The Future of Epicardial Interventions.