Ground-breaking scientific research and new philosophical perspectives currently challenge our anthropocentric cultural assumptions of the vegetal world. As humanity begins to grapple with the urgency imposed by climate change, reconsidering human/plant relationships becomes essential to grant a sustainable future on this planet. It is in this context that a multifaceted approach to plant-life can reveal the importance of ecological interconnectedness and lead to a more nuanced consideration of the variety of living organisms and ecosystems with which we share the planet. In Botanical Speculations, researchers, artists, art historians, and activists collaboratively map the uncharted territories of new forms of botanical knowledge. This book emerges from a symposium held at the School of the Art Institute of Chicago in September 2017, and capitalizes on contemporary art’s ability to productively unhinge scientific theories and certainties in order to help us reconsider unquestioned beliefs about this living world.