Based on the proceedings of the Bone-Biomaterial Interface Workshop held in Toronto, Canada, December 1990, addresses the questions which have arisen during this period of evolution from inert to active materials in orthopedic, dental, and maxillofacial implants with specific reference to the bone-biomaterial interface. The seven parts of the volume reflect the seven sessions of the workshop, dealing with materials issues, protein adsorption, cell and tissue reactions, mechanical influences on interfacial biology, retrieval analysis, and the industrial context. Annotation copyrighted by Book News, Inc., Portland, OR

Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. - Presents a specific focus on the development and use of biomaterials in the oral environment - Discusses the basic science of the dental interface and its clinical applications - Contains important coverage on the monitoring and analysis of the dental implant interface

Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and Interfaces for Biomaterials summarizes the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue. The first part of the book reviews the way biomaterial surfaces form. Part Two then discusses ways of monitoring and characterizing surface structure and behavior. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility. Surfaces and Interfaces for Biomaterials will be a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine.

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Written by respected experts in the field, Biomaterials in Orthopedics discusses bioabsorbable biomaterials for bone repair, nondegradable materials in orthopaedics and delivery systems. Topics in this text include biocompatibility and the biomaterial/tissue interface; self-reinforced bioabsorbable devices and guided regeneration; bone substitutes,

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration.

This volume presents a comprehensive review on the actual trends in basic and applied research on biomaterials, in hard tissue repair and reconstruction, as well as their consequences for both industry and society. The importance of methods for high-resolution characterization are highlighted, the crucial problem of interactions is illustrated by a variety of methods which include implantation, cell culture, and microstructural examination. Also included are papers on the recent developments in joint replacement, maxillo facial, nerve and ligament repair, and dental implants.

The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research

Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. - Reviews and discusses all aspects of orthopedic implant osseointegration - Provides conceptual implants for bone fracture fixation and joint replacement - Offers novel ideas for the development of orthopedic implants with superior osseointegration