A thrilling story of scientific detective work and medical potential that illuminates the newly understood role of microglia—an elusive type of brain cell that is vitally relevant to our everyday lives. “The rarest of books: a combination of page-turning discovery and remarkably readable science journalism.”—Mark Hyman, MD, #1 New York Times bestselling author of Food: What the Heck Should I Eat? NAMED ONE OF THE BEST BOOKS OF THE YEAR BY WIRED Until recently, microglia were thought to be helpful but rather boring: housekeeper cells in the brain. But a recent groundbreaking discovery has revealed that they connect our physical and mental health in surprising ways. When triggered—and anything that stirs up the immune system in the body can activate microglia, including chronic stressors, trauma, and viral infections—they can contribute to memory problems, anxiety, depression, and Alzheimer’s. Under the right circumstances, however, microglia can be coaxed back into being angelic healers, able to make brain repairs in ways that help alleviate symptoms and hold the promise to one day prevent disease. With the compassion born of her own experience, award-winning journalist Donna Jackson Nakazawa illuminates this newly understood science, following practitioners and patients on the front lines of treatments that help to “reboot” microglia. In at least one case, she witnesses a stunning recovery—and in others, significant relief from pressing symptoms, offering new hope to the tens of millions who suffer from mental, cognitive, and physical health issues. Hailed as a “riveting,” “stunning,” and “visionary,” The Angel and the Assassin offers us a radically reconceived picture of human health and promises to change everything we thought we knew about how to heal ourselves.

One day Donna Jackson Nakazawa found herself lying on the floor to recover from climbing the stairs. That’s when it hit her. She was managing the symptoms of the autoimmune disorders that had plagued her for a decade, but she had lost her joy. As a science journalist, she was curious to know what mind-body strategies might help her. As a wife and mother she was determined to get her life back. Over the course of one year, Nakazawa researches and tests a variety of therapies including meditation, yoga, and acupuncture to find out what works. But the discovery of a little-known branch of research into Adverse Childhood Experiences causes her to have an epiphany about her illness that not only stuns her—it turns her life around. Perfect for readers of Gretchen Rubin's The Happiness Project, Nakazawa shares her unexpected discoveries, amazing improvements, and shows readers how they too can find their own last best cure.

Kael Saunders loves to dominate handsome, masculine men like himself. Being in charge is his way of life, whether it be in his work with the secret intelligence service MI6, his empty and lonely personal life, or in the dungeon in his expensive flat on the River Thames. The last thing this no-nonsense, strict, and disciplined secret agent expects when he is out on a hit chasing down a gun runner is to fall in love with Angel Button, a young man desperate for the love and guidance of a Daddy. After spending his formatives years in foster care and then with his selfish, social-climbing mother and stepfather, Angel wants security, stability, and a man to love. However, Angel also has a passion for being spanked and restrained. Two very different men find love in a world of skilled assassins, Bosnian terrorists, and dungeon play. But can they make it work?

An examination of the link between Adverse Childhood Events (ACE's) and adult illnesses.

In the Russian winter of 1878 a shy, aristocratic young woman named Vera Zasulich walked into the office of the governor of St. Petersburg, pulled a revolver from underneath her shawl, and shot General Fedor Trepov point blank. "Revenge!," she cried, for the governor's brutal treatment of a political prisoner. Her trial for murder later that year became Russia's "trial of the century," closely followed by people all across Europe and America. On the day of the trial, huge crowds packed the courtroom. The cream of Russian society, attired in the finery of the day, arrived to witness the theatrical testimony and deliberations in the case of the young angel of vengeance. After the trial, Vera became a celebrated martyr for all social classes in Russia and became the public face of a burgeoning revolutionary fervor. Dostoyevsky (who attended the trial), Turgenev, Engels, and even Oscar Wilde all wrote about her extraordinary case. Her astonishing acquittal was celebrated across Europe, crowds filled the streets and the decision marked the changing face of Russia. After fleeing to Switzerland, Vera Zasulich became Russia's most famous "terroristka," inspiring a whole generation of Russian and European revolutionaries to embrace violence and martyrdom. Her influence led to a series of acts that collectively became part of "the age of assassinations." In the now-forgotten story of Russia's most notorious terrorist, Ana Siljak captures Vera's extraordinary life story--from privileged child of nobility to revolutionary conspirator, from assassin to martyr to socialist icon and saint-- while colorfully evoking the drama of one of the world's most closely watched trials and a Russia where political celebrities held sway.

From NYT bestselling author Brent Weeks comes the first novel in his breakout fantasy trilogy in which a young boy trains under the city's most legendary and feared assassin, Durzo Blint. For Durzo Blint, assassination is an art -- and he is the city's most accomplished artist. For Azoth, survival is precarious. Something you never take for granted. As a guild rat, he's grown up in the slums, and learned to judge people quickly -- and to take risks. Risks like apprenticing himself to Durzo Blint. But to be accepted, Azoth must turn his back on his old life and embrace a new identity and name. As Kylar Stern, he must learn to navigate the assassins' world of dangerous politics and strange magics -- and cultivate a flair for death.

The murder of a world-famous physicist raises fears that the Illuminati are operating again after centuries of silence, and religion professor Robert Langdon is called in to assist with the case.

From the Foreword: [An] astounding book . . . put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise.--Dr. Douglas Kerr, Director, Johns Hopkins Transverse Myelitis Center.

They call themselves "January 30", after the date of a British massacre in Belfast. They are allied with no one, killing American diplomats and KGB agents, Arabs and Israelis, IRA gunmen and Loyalist soldiers. But they are definitely the enemies of peace--and they are plotting an assassination that will shatter an uneasy truce that reigns in Ireland. Former IRA enforcer Sean Dillon must hunt down January 30 before they kill again. Before they spark another war. Before Dillon himself falls prey to the ultimate assassin--the Angel of Death...

From internationally bestselling author Sandrone Dazieri and featuring “two of the most intriguing detectives to have emerged in recent years” (Daily Mail, London) comes the “explosive” (Booklist, starred review) second thriller in the Caselli and Torre series. In Rome, a passenger train speeds into the city’s main station, its first-class car full of dead bodies, the macabre discovery of which falls to Deputy Police Commissioner Colomba Caselli. The police then receive a claim of responsibility and the threat of more murders to come. But neither Caselli nor her eccentrically brilliant ally, Dante Torre, are ready to buy the terrorist link. As the two unconventional investigators chip away at what the perpetrator wants everyone to believe, they put their own lives in jeopardy. But Dante’s bizarre and traumatic past enables him to see what others miss, and in this case, to connect with a kindred spirit of sorts, a woman named Giltine who also experienced an intense trauma—one from which she emerged damaged and full of murderous intent. Making her especially lethal is that the rare mental illness she suffers from has her believing she’s already dead. When Colomba and Dante find themselves on the outs with law enforcement they’re entirely on their own, faced with the responsibility of making sure the waters of Venice don’t turn red with blood.