For two decades, Swine in the Laboratory: Surgery, Anesthesia, and Experimental Techniques has been the most respected practical technical guide for medical and veterinary researchers using swine as experimental animals. Extensively updated and expanded since the publication of the second edition in 2007 and now sponsored by the American College of

Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...

Experimental surgery is an important link for the development in clinical surgery, research and teaching. Experimental surgery was part of the most important surgical discoveries in the past century. Since 1901 nine Nobel Prizes have been awarded to the pioneers had remarkable achievements in the basic or practical surgery. In recent 20 years, experimental surgery has achieved new advances, like laparoscopic and robotic surgery, tissue engineering, and gene therapy which are widely applied in clinic surgery. The present book covers wide experimental surgery in preclinical research models subdivided in two volumes. Volume I introduces surgical basic notions, techniques, and different surgical models involved in basic experimental surgery and review the biomechanical models, ischemia/reperfusion injury models, repair and regeneration models, and organ and tissue transplantation models, respectively. Volume II introduces several specific experimental models such as laparoscopic and bariatric experimental surgical models. The second volume also introduces graft-versus-host disease, and other experimental models. Review the advances and development of recent techniques such as tissue engineering, organ preservation, wound healing and scarring, gene therapy and robotic surgery. The book documents the enormous volume of knowledge we have acquired in the field of experimental surgery. In this book, we have invited experts from the United States, Canada, France, Germany, China, Japan, Korea, UK, Sweden, Netherland, Hungary and Turkey to contribute 36 chapters in the fields of their expertise. These two volumes are the compilation of basic experimental surgery and updated advances of new development in this field that will be invaluable to surgeons, residents, graduate students, surgical researchers, physicians, immunologists, veterinarians and nurses in surgery.

Since its first publication in 1936, Sabiston Textbook of Surgery has been regarded as the preeminent source for definitive guidance in all areas of general surgery. The 20th edition continues the rich tradition of quality that has made this classic text synonymous with the specialty and a part of generations of surgery residents and practitioners. Meticulously updated throughout, this classic text concisely covers the breadth of material needed for certification and practice of general surgery. Detailed, full-color intraoperative illustrations capture key teaching moments, allowing you to better understand the basic science of surgery, make the most informed decisions and achieve optimal outcomes for every patient. Understand the underlying science and its clinical application to make informed surgical decisions and achieve optimal outcomes. Overcome tough challenges, manage unusual situations, and avoid complications with the most trusted advice in your field. Get the depth of coverage you need in an easily accessible, single volume organized by organ and along traditional lines beginning with principles common to surgical specialties including fluid and electrolyte management, metabolic support, and wound healing. Subsequent sections review the management of injury, transplantation, oncology, breast, endocrine, and abdominal procedures. Explore topics encountered by general surgery residents in training as well as in-depth coverage of subspecialty areas including head and neck, thoracic, vascular, urology, neurosurgery, pediatrics, and gynecology. Visually grasp and retain difficult concepts thanks to a full-color design featuring an abundance of illustrations, intraoperative photographs, and tables as well as more schematic diagrams that facilitate the comprehension of surgical techniques and procedures. Glean all essential, up-to-date, need-to-know information about the latest surgical perspectives and approaches to treatment including innovations in minimally invasive surgery and percutaneous devices. Streamline clinical decision making with an increased number of schematic diagrams and key data on surgical outcomes. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.

This book initiates the descriptions of the practical performance of different hysterectomies with conventional and robotically assisted laparoscopy, laparotomy and vaginal surgery. Laparoscopic hysterectomy has been out as an additional technique for hysterectomies for the last couple of decades. As the necessary light, augmentation and advanced skill has only been introduced into this already 200 year old surgical procedure within the last few decades by laparoscopy, the editors aim to look at the laparoscopic procedures followed by the traditional techniques of hysterectomy with laparotomy and vaginal surgery.

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. - Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research - Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology - Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. "[Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book." —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust.

To diminish the learning curve associated with using swine as models, Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition provides practical technical information for the use of swine in biomedical research. The book focuses on models produced by surgical and other invasive procedures, supplying the ba