Textbook Of Cell Signalling In Cancer
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Author |
: Jacques Robert |
Publisher |
: Springer |
Total Pages |
: 341 |
Release |
: 2015-02-17 |
ISBN-10 |
: 9783319143408 |
ISBN-13 |
: 3319143409 |
Rating |
: 4/5 (08 Downloads) |
Synopsis Textbook of Cell Signalling in Cancer by : Jacques Robert
This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis. This comprehensive reference text is based on the master’s courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.
Author |
: Kasirajan Ayyanathan |
Publisher |
: CRC Press |
Total Pages |
: 402 |
Release |
: 2014-06-20 |
ISBN-10 |
: 9781482299458 |
ISBN-13 |
: 1482299453 |
Rating |
: 4/5 (58 Downloads) |
Synopsis Cancer Cell Signaling by : Kasirajan Ayyanathan
This title includes a number of Open Access chapters.Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developi
Author |
: Christoph Wagener |
Publisher |
: John Wiley & Sons |
Total Pages |
: 356 |
Release |
: 2017-01-27 |
ISBN-10 |
: 9783527800476 |
ISBN-13 |
: 3527800476 |
Rating |
: 4/5 (76 Downloads) |
Synopsis Cancer Signaling, Enhanced Edition by : Christoph Wagener
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Author |
: Christoph Wagener |
Publisher |
: John Wiley & Sons |
Total Pages |
: 356 |
Release |
: 2016-12-12 |
ISBN-10 |
: 9783527336586 |
ISBN-13 |
: 3527336583 |
Rating |
: 4/5 (86 Downloads) |
Synopsis Cancer Signaling by : Christoph Wagener
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Author |
: Kakoli Bose |
Publisher |
: Springer Nature |
Total Pages |
: 587 |
Release |
: 2019-11-25 |
ISBN-10 |
: 9789813298163 |
ISBN-13 |
: 9813298162 |
Rating |
: 4/5 (63 Downloads) |
Synopsis Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach by : Kakoli Bose
Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Author |
: Kasirajan Ayyanathan |
Publisher |
: CRC Press |
Total Pages |
: 412 |
Release |
: 2014-06-20 |
ISBN-10 |
: 9781771880671 |
ISBN-13 |
: 1771880678 |
Rating |
: 4/5 (71 Downloads) |
Synopsis Cancer Cell Signaling by : Kasirajan Ayyanathan
Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an overview of the field and how various cell biology techniques are used to better understand cancer on a cellular level. This easily accessible reference volume offers a comprehensive look at the field of cancer cell signaling. Edited by a researcher from Florida Atlantic University, Cancer Cell Signaling: Targeting Signaling Pathways Towards Therapeutic Approaches to Cancer is an authoritative and easy-to-use reference.
Author |
: Malay Chatterjee |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 334 |
Release |
: 2011-12-02 |
ISBN-10 |
: 9781461407300 |
ISBN-13 |
: 1461407303 |
Rating |
: 4/5 (00 Downloads) |
Synopsis Cell Signaling & Molecular Targets in Cancer by : Malay Chatterjee
This book provides an overview of critical components of cell signaling machinery and its role in epithelial morphogenesis, proliferation, invasions and angiogenesis in human cancer and discusses novel types of protein kinase pathways.
Author |
: Martha Robles-Flores |
Publisher |
: Humana |
Total Pages |
: 300 |
Release |
: 2020-11-12 |
ISBN-10 |
: 1071607588 |
ISBN-13 |
: 9781071607589 |
Rating |
: 4/5 (88 Downloads) |
Synopsis Cancer Cell Signaling by : Martha Robles-Flores
This fully updated edition provides the most recent advances in cancer cell signaling knowledge combined with some discussion of the current challenges and prospects in cancer therapy. Beginning with an important section on cancer resistance, the main obstacle to effective cancer therapy, the book continues with chapters exploring state-of-the-art methods in epigenetic control of cancer, metastasis promotion, as well as a variety of new technologies in the study of cancer. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Third Edition serves as an ideal guide to researchers seeking to overcome the challenges in the vital field of cancer cell signaling.
Author |
: Francesco Pezzella |
Publisher |
: Oxford University Press |
Total Pages |
: 505 |
Release |
: 2019-05-02 |
ISBN-10 |
: 9780198779452 |
ISBN-13 |
: 0198779453 |
Rating |
: 4/5 (52 Downloads) |
Synopsis Oxford Textbook of Cancer Biology by : Francesco Pezzella
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.
Author |
: Francesco Pezzella |
Publisher |
: Oxford University Press |
Total Pages |
: 505 |
Release |
: 2019-05-06 |
ISBN-10 |
: 9780191084867 |
ISBN-13 |
: 0191084867 |
Rating |
: 4/5 (67 Downloads) |
Synopsis Oxford Textbook of Cancer Biology by : Francesco Pezzella
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.