In this issue of Urologic Clinics of North America, guest editor Dr. Kevin R. Loughlin brings his considerable expertise to the topic of Testosterone. With about 2 out of 10 men older than 60 years having low testosterone (American Urological Association), coupled with an aging population, this issue is an important resource for all urologists for effectively treating men and improving outcomes. It provides a current update on testosterone in men from top experts in the field, covering prostate cancer treatment, the use of anabolic steroids, hypogonadism, testosterone replacement, and more. Contains 15 practice-oriented topics including current management and controversies surrounding andropause; testosterone and male sexual function; the interplay of testosterone and dihydrotestosterone in prostate cancer; and more. Provides in-depth clinical reviews on testosterone, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Urologic Clinics of North America, guest editor Dr. Kevin R. Loughlin brings his considerable expertise to the topic of Testosterone. With about 2 out of 10 men older than 60 years having low testosterone (American Urological Association), coupled with an aging population, this issue is an important resource for all urologists for effectively treating men and improving outcomes. It provides a current update on testosterone in men from top experts in the field, covering prostate cancer treatment, the use of anabolic steroids, hypogonadism, testosterone replacement, and more. - Contains 15 practice-oriented topics including current management and controversies surrounding andropause; testosterone and male sexual function; the interplay of testosterone and dihydrotestosterone in prostate cancer; and more. - Provides in-depth clinical reviews on testosterone, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of the Urologic Clinics covers timely topics pertinent to Men's Health, including The Role of Primary Care in Men’s Health, Changes in Male Fertility in the Last Two Decades, The Aging Male, and Pre-adolescent issues as risk factors for adult male health.

The relationship between testosterone and prostate cancer physiology resulted in a Nobel Prize almost 5 decades ago; scientists have been studying testosterone and its relationship to heart health, diabetes, bone density, and muscle development throughout the subsequent 50 years. Included in this issue is the clinical experience and research expertise of many of the leaders in this field.

This issue provides much needed updates since Dr. Sheinfeld’s issue published in 2007. Dr. Lin has assembled expert authors to provide clinicians with the full breadth of clinical updates on testicular cancer. New to this issue are articles on clinical outcomes, survivorship, and several articles on the management of Nonseminomatous Germ Cell Tumors.

This issue of Medical Clinics of North America, guest edited by Robert E. Brannigan, MD, is devoted to Urology. Articles in this outstanding issue include: Prostate Cancer Screening; Treatment Modalities and Outcomes for Prostate Cancer; Kidney, Ureteral, and Bladder Cancer: A Primer for the Internist; Testicular Cancer: Epidemiology, Diagnosis, and Treatment; Urinary Stone Disease: Diagnosis, Medical Therapy, and Surgical Management; Male Voiding Dysfunction, BPH, and Urinary Retention; Female Voiding Dysfunction and Urinary Incontinence; Penile and Urethral Reconstructive Surgery; Male Infertility Diagnosis and Treatment in the Era of IVF/ICSI; Sexual Dysfunction: Behavioral, Medical, and Surgical Therapies; Hypogonadism: Therapeutic Risks, Benefits, and Outcomes; Cutaneous Diseases of the External Genitalia; Urological Emergencies; Telemedicine: Early Experience in the Urology Clinic; and Men’s Health Programs: The Intersection of Internal Medicine and Urology.

In this issue of Urologic Clinics, Guest Editors Alan W Shindel and Tom F. Lue bring their considerable expertise to the topic of Sexual Dysfunction. Top experts in the field cover key topics such as Sexual Wellness in transgender persons; Energy-based Therapies for ED; Oncology Survivorship and Sexual Wellness for Men and Women; Sexual Wellness in Gay, Lesbian, and Bisexual Patients; and more. Provides in-depth, clinical reviews in Sexual Dysfunction, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 16 relevant, practice-oriented topics including Management of Penile Fracture; Physiology of Erection and Pathophysiology of Erectile Dysfunction; Stem Cell and Gene-Based Therapy for ED; Management of Priapism; and more.

Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an "antiaging tonic," testosterone's reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.

This issue of the Urologic Clinics covers office-based procedures in urology. There are a wealth of urologic procedures that can be done in the office setting, offering reduced risks to the patient, less stress, and better recovery time, as well as a more favourable reimbursement for the physician. Articles include more common issues such as stone management, ultrasound/prostate biopsy, and vasectomy, as well as infusion therapy, biofeedback, and office anesthesia.

Dr. Samir Taneja, Consulting Editor, is stepping into the Guest Editor role for this issue of Urologic Clinics devoted to Prostate Cancer. He has assembled top experts to address the latest advances in the diagnosis and treatment of prostate cancer. Articles are devoted to the following topics: Whom to Biopsy: Pre-Diagnostic Risk Stratification with Biomarkers, Nomograms, and Risk Calculators; How to Biopsy: Transperineal vs. Tranrectal, Saturation vs. Targeted: What’s the Evidence; Pre-Diagnostic Risk and Assessment with Imaging and Image-guided Biopsy; Whom to treat: Post-Diagnostic Risk Assessment with Gleason score, Risk Models, and Genomic Classifier; Strategies for Staging and Utilization of Imaging; Contemporary Active Surveillance: Candidate Selection, Follow-up Tools, and Expected Outcomes; Focal Ablation of Early Stage Prostate Cancer: Candidate Selection, Treatment Guidance, and Assessment of Outcome; Extent of Lymphadenectomy at Time of Prostatectomy: An Evidence-based Approach; How to Radiate the Prostate: Hypofractionation, Sterotactic Body Radiation Therapy, and Conventional Intensity-Modulated Radiotherapy; Managing Relapse after Surgical Therapy: Adjuvant vs. Salvage Therapy; Newly diagnosed Metastatic Prostate Cancer – Has the Paradigm Changed; Role of Local therapy in Oligometastatic Prostate Cancer: Should we Expect Cure; Approaching the High-Risk Patient; and Castration-Resistant Prostate Cancer: An Algorithmic Approach. Readers will come away with state-of-the-art information on strategies for diagnosing, treating, and managing prostate cancer.