Essentials of Glycobiology

Essentials of Glycobiology
Author :
Publisher : CSHL Press
Total Pages : 694
Release :
ISBN-10 : 0879696818
ISBN-13 : 9780879696818
Rating : 4/5 (18 Downloads)

Synopsis Essentials of Glycobiology by : Ajit Varki

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Tumor Microenvironments in Organs

Tumor Microenvironments in Organs
Author :
Publisher : Springer Nature
Total Pages : 155
Release :
ISBN-10 : 9783030362140
ISBN-13 : 3030362140
Rating : 4/5 (40 Downloads)

Synopsis Tumor Microenvironments in Organs by : Alexander Birbrair

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Eosinophilic Gastrointestinal Diseases

Eosinophilic Gastrointestinal Diseases
Author :
Publisher : Clinics: Internal Medicine
Total Pages : 0
Release :
ISBN-10 : 1437704891
ISBN-13 : 9781437704891
Rating : 4/5 (91 Downloads)

Synopsis Eosinophilic Gastrointestinal Diseases by : Glenn T. Furuta

Drs. Glen Furuta and Dan Atkins have assembled an in-depth look at Eosinophilic Gastrointestinal Diseases as related to allergy with topics such as "Basic pathogenetic mechanisms of Eosinophilic Esophagitis", "Nutritional management of patients with food allergies and EGIDs", "Chemotactic factors role in EGIDs", "Biomarkers associated with allergic diseases", "Association of other allergic diseases with EGIDs" and much more!

Lung Development

Lung Development
Author :
Publisher : Springer
Total Pages : 464
Release :
ISBN-10 : 9781461475378
ISBN-13 : 1461475376
Rating : 4/5 (78 Downloads)

Synopsis Lung Development by : Claude Gaultier

Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.

Single Domain Antibodies

Single Domain Antibodies
Author :
Publisher : Humana Press
Total Pages : 580
Release :
ISBN-10 : 161779967X
ISBN-13 : 9781617799679
Rating : 4/5 (7X Downloads)

Synopsis Single Domain Antibodies by : Dirk Saerens

The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications. In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Stem Cell-Based Therapy for Lung Disease

Stem Cell-Based Therapy for Lung Disease
Author :
Publisher : Springer Nature
Total Pages : 260
Release :
ISBN-10 : 9783030294038
ISBN-13 : 303029403X
Rating : 4/5 (38 Downloads)

Synopsis Stem Cell-Based Therapy for Lung Disease by : Janette K. Burgess

This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

The Extracellular Matrix: an Overview

The Extracellular Matrix: an Overview
Author :
Publisher : Springer Science & Business Media
Total Pages : 429
Release :
ISBN-10 : 9783642165559
ISBN-13 : 3642165559
Rating : 4/5 (59 Downloads)

Synopsis The Extracellular Matrix: an Overview by : Robert Mecham

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
Author :
Publisher : Woodhead Publishing
Total Pages : 392
Release :
ISBN-10 : 9780081008522
ISBN-13 : 008100852X
Rating : 4/5 (22 Downloads)

Synopsis Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair by : Mario Barbosa

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. - Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration - Explores protein and peptides from the fundamentals, to processing and applications - Written by an international group of leading biomaterials researchers

The Oxford Handbook of Evolutionary Medicine

The Oxford Handbook of Evolutionary Medicine
Author :
Publisher : Oxford University Press
Total Pages : 967
Release :
ISBN-10 : 9780192506788
ISBN-13 : 0192506781
Rating : 4/5 (88 Downloads)

Synopsis The Oxford Handbook of Evolutionary Medicine by : Martin Brüne

Medicine is grounded in the natural sciences, where biology stands out with regard to our understanding of human physiology and the conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, the macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system. Moreover, many adaptations to past ecologies have actually turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. One could add depression, anxiety, and other psychiatric conditions to the list. The Oxford Handbook of Evolutionary Medicine is a compilation of up-to-date insights into the evolutionary history of ourselves as a species, exploring how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine is valuable reading for students as well as scholars in the fields of medicine, biology, anthropology and psychology.