This research guidebook is to provide the reader with current DoD initiatives, policy and guidance, and identification of newly formed organizations in M & S. This book will provide a better understanding of how models are developed, applied in simulations and their value in analysis; and more importantly, it provides a quick reference for the application of these tools in the development of weapon systems. This guidebook offers lessons learned from current acquisition managers, advice on management practices, points of contact (POCs) and how to access M & S data bases.