Epigram Books Fiction Prize 2016 Finalist Landon Locke is no ordinary barista. A man of many names and identities, he has lived though many lifetimes, but his memory spans only days. Danger brews as Landon struggles to piece together reality through his fog of amnesia. A mysterious organisation called CODEX bent on hunting him down, a man named John who claims to be a friend, and women from Landon's past who have come back to haunt him. As CODEX closes in, he finds himself increasingly backed into a corner. Battling an unreliable memory, Landon is forced to make a choice: who can he trust?

SIMPL (Synchronous Interprocess Messaging Project for Linux) is discussed at many different levels. At its most fundamental, SIMPL is a set of library functions which allow the passing of encapsulated messages between cooperating processes. On another level, SIMPL is an active open source project which began over a decade ago. Over the years this project has accumulated an extensive body of sample code and extensions. SIMPL is also a great way to design software applications where complexity is encapsulated in separate, easily testable, readily extendable modules. The current state of software development is compared to the hardware world before the advent of integrated circuit chips. The term softwareIC is coined to describe the software equivalent of the integrated circuit. The SIMPL toolkit, along with tokenized messaging and the SIMPL testing framework is shown to be a great way to build these softwareICs. Several are illustrated throughout the book.

At its most fundamental, SIMPL is a set of library functions which allow the passing of encapsulated messages between cooperating processes. These processes may be local to one host computer or spread over a network.On another level, SIMPL is an active open source project which began over a decade ago. Over the years this project has accumulated an extensive body of sample code and extensions. Currently SIMPL libraries are supported for C/C++, Python, JAVA and Tcl programming languages. A sample Sudoku puzzle solver project illustrates all these in a single application.

Covers the latest research on a sensitive and controversial topic in a professional and well researched manner. Provides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not. Related title by Co-author Geert Molenbergh has sold more than 3500 copies world wide. Provides dual viewpoints: from scientists in the industry as well as regulatory authorities.

The complexity of Surrogacy is arguably made even more so by the very nature of it being a decision many families reach due to the greatest of emotional challenges. There are so many opportunities for things to go wrong, but also the greatest of happy outcomes for so many families too. As a specialist surrogacy lawyer and a surrogate in 2018, Sarah Jefford has observed many surrogacy teams both flourish and struggle, and that has led to this very important book. In order to maximise every potential for things to go well for both intended parents and surrogate mothers, we need to make informed decisions that protect the interests of everyone involved, but most importantly that are in the best interests of the children - those who are already here, and those who will be in the future. If you want to know answers to the questions of how does surrogacy work, and the surrogate mother process, then this book will be your best place to start. But keep it handy throughout the entire process so that as your journey progresses, you will be able to understand the many aspects of surrogate pregnancy, intended parents roles, and each other's vital roles in creating a family together.

This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

This book constitutes the thoroughly refereed post-proceedings of the 12th International Workshop on Security Protocols, April 2004. The book presents 21 revised full papers presented together with edited transcriptions of some of the discussions following the presentations. Among the topics addressed are authentication, anonymity, verification of cryptographic protocols, mobile ad-hoc network security, denial of service, SPKI, access control, timing attacks, API security, biometrics for security, and others.

The rapidly changing climatic condition coupled with habitat destruction, aquatic pollution and increasing anthropogenic pressure on water bodies have resulted in decline of many important fish population and some of them even become endangered. As of now the breeding protocol for seed production in captivity is developed for only handful of fish species and mostly their seed is collected from natural resources for aquaculture. This factor limits the efforts for species diversification in aquaculture. There are approaches/ technologies to generate seed of such fish species for aquaculture, especially the species that are too large to propagate in captivity or species those do not response to hormonal treatments due to stress of confinement. One of the viable approach is surrogate broodstock development using adult fish as the recipient. The obvious advantage of using adult fish as recipient is that, the donor-derived gametes can be generated within few months after stem cell transplantation; oppose to using embryos or young hatchlings those take years together to attain sexual maturity. Note: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

The real life behind Helen Hunt’s Oscar-nominated performance in The Sessions: “A provocative and unusual book about a provocative and unusual profession” (Booklist). For the past forty years, Cheryl Cohen Greene has worked as a surrogate partner, helping clients to confront and ultimately accept their sexuality. In this riveting memoir, Cohen Greene shares some of her most moving cases, and also reveals her own sexual coming-of-age. Beginning with a rigid Catholic upbringing in the 1950s, where she was taught to think sex and sexual desires were unnatural and wrong, Cohen Greene struggled to reconcile her sexual identity. In the 1960s Sexual Revolution, Cohen Greene found herself drawn to alternative sexual paths, and ultimately achieved a rich and rewarding career as a surrogate partner. Sex surrogacy as a profession was first developed by noted sex researchers Masters and Johnson in the 1960s, and since its inception has remained in the shadows. An Intimate Life offers a candid look into the personal and professional life of a surrogate partner, examining the cultural and emotional ramifications of pursuing something most people consider taboo. The memoir opens with Cohen Greene’s work with Berkeley-based poet and journalist Mark O’Brien, who was confined to an iron lung after contracting polio at age six. His short essay “On Seeing A Sex Surrogate” was adapted into the film The Sessions starring John Hawkes and Helen Hunt as Cheryl T. Cohen Greene.

Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.