A luminary in the field of cerebrovascular surgery brings his pace-setting work on the surgical management of moyamoya disease to the neurosurgical community When the rare stroke strikes in children and youth, a likely cause is the idiopathic disease moyamoya, characterized by the slow and progressive stenosis and occlusion of the internal carotid artery and the arteries of the circle of Willis. A result of these stenoses is the formation of collaterals that are typically small and fragile, and liable to rupture. While there is no cure for moyamoya, a variety of surgical procedures can be performed to re-establish and maintain adequate blood supply to the affected brain areas. The procedures described here include various revascularization techniques and recommended bypasses. Key Features: With contributions from the world's most renowned bypass surgeons Perioperative management and considerations An overall practical approach to this painstaking high-end surgery Detailed criteria for analyzing the situation and choosing the appropriate procedure General principles of bypass surgery, direct and indirect revascularization, and combined revascularization techniques Step-by-step descriptions of these procedures Rescue strategies when repeat surgery is necessary Surgical Techniques in Moyamoya Vasculopathy is an indispensable guide for the experienced neurovascular surgeon.

Moyamoya Disease: Diagnosis and Treatment covers the key clinical disciplines involved in managing patients with moyamoya disease, including diagnostic work up, imaging, neurocognitive evaluation, and surgical options for pediatric and adult patients. The text and accompanying videos provide neurosurgeons and other health professionals treating Moyamoya patients with all the information they need to make the right diagnostic and surgical decisions. Key Features: Includes online access to videos and animations, narrated by Dr. Wanebo, demonstrating surgical techniques discussed in the book Written and edited by world-renowned experts at the Barrow Neurological Institute and other centers of excellence focused on Moyamoya Covers these dynamic topics in Moyamoya: cortical microvasculature, genetics, neuropsychiatric evaluation, and endovascular therapy Contains detailed illustrations and descriptions of technical aspects of treatment such as the direct and indirect methods of revascularization All neurosurgeons and neurologists caring for Moyamoya patients will find this book to be an important reference that they will consult often in their daily practice.

Toole's Cerebrovascular Disorders was the first modern book devoted to care of the stroke, originally published more than 40 years ago. This is a completely revised and updated sixth edition of the highly respected standard for stroke diagnosis and treatment. Dr James Toole has stayed on as a consultant for the text, and Drs E. Steve Roach, Kerstin Bettermann, and Jose Biller have reworked Dr Toole's book to include chapters on genetics, pregnancy-related stroke, and acute treatments. The practical focus of the book has not changed, retaining its emphasis on bedside diagnosis and treatment. Easily accessible both for stroke specialists and residents, the sixth edition has been modernized to keep pace with the rapid expansion of knowledge in stroke care and includes evidence-based recommendations, the latest technology and imaging, and risk factors. The text is supplemented with more than 200 images, many in color.

Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. They emphasize the need for clinical reasoning, integrative thinking, problem-solving, communication, teamwork and self-directed learning – all desirable generic skills for health care professionals. This book is a teaching tool that bridges the gap between textbook information and everyday experience of clinicians 'in the trenches'. Leading practitioners bring a practical approach to these complex conditions, highlighting specific areas of diagnostic uncertainty in evaluation and treatment. Each case is taken from real-world clinical practice and reviews the diagnostic and treatment process in a systematic manner, identifying common challenges and potential pitfalls. This concise and useful guide in the Common Pitfalls series provides a step-by-step guide for everyday clinical practice, invaluable to anyone dealing with cerebrovascular disease on a front-line basis. The intended readership is trainees and non-specialist practitioners in neurology, stroke medicine, and neurosurgery.

An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.

Emphasizes the research activities of Germany’s Nauheim Institute of the Max Planck Society and its group of investigators both past and present, in the field of collateral artery growth. Incorporates a multidisciplinary in vivo approach to the study of arteriogenesis that includes molecular approaches with classical physiology and immunohistochemistry. Full color throughout and well illustrated.

Moyamoya disease is a rare cerebrovascular disease most prevalent in East Asian countries. Thanks to new diagnostic capabilities, the number of cases discovered, including asymptomatic patients, has been increasing steadily. However, asymptomatic from the clinical point of view does not necessarily mean that there are no subjacent problems. Indeed, many patients harbour cognitive decline long before they exhibit clinical or radiological manifestations. The only effective treatment is surgical revascularization, either direct, indirect, or combined. Many posit that preventive surgical treatment should be considered even in asymptomatic moyamoya patients, particularly in the paediatric age group. This book expands on these ideas and examines the various aspects of this dreadful disease.

Moyamoya disease (MMD) was first reported as a new entity among vascular disorders in 1957. Named for the abnormal vascular networks found around the occluded distal internal carotid artery, it is the most common pediatric cerebrovascular disease in East Asia. In recent years large amounts of data on MMD have been collected and important investigations have been carried out in Japan and Korea, even as the pathophysiology of the disease remains to be discovered. This monograph covers a diversity of topics and presents a systematic compilation of the data and current status of MMD in clinical practice and basic research. With contributions by more than 70 authors, the book includes sections on genetics, computational analysis of hemodynamic shear stress, new imaging techniques, and endovascular treatment of MMD, along with practical applications and future directions for gene and stem cell therapies. For neurosurgeons as well as neurologists and pediatricians, this volume will help lead to more efficient and informed management of MMD.

Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation

Core Topics in Neuroanesthesia and Neurointensive Care is an authoritative and practical clinical text that offers clear diagnostic and management guidance for a wide range of neuroanesthesia and neurocritical care problems. With coverage of every aspect of the discipline by outstanding world experts, this should be the first book to which practitioners turn for easily accessible and definitive advice. Initial sections cover relevant anatomy, physiology and pharmacology, intraoperative and critical care monitoring and neuroimaging. These are followed by detailed sections covering all aspects of neuroanesthesia and neurointensive care in both adult and pediatric patients. The final chapter discusses ethical and legal issues. Each chapter delivers a state-of-the art review of clinical practice, including outcome data when available. Enhanced throughout with numerous clinical photographs and line drawings, this practical and accessible text is key reading for trainee and consultant anesthetists and critical care specialists.