This book covers clinical management including diagnosis, localization and physiology, for a number of clinical diseases treated by endocrinologists and surgeons. Following each chapter there is a 3-4 page biographical sketch of the person behind the clinical endocrinopathy, whose name is closely associated with the disease. The field of endocrine surgery is rich in history and this is the first text to bring together in one place the person behind the disease and the pioneers of the field. The text covers both the current management of endocrine surgical diseases, and also provides a historical background by highlighting the person in whom these discoveries were named after. Surgical Endocrinopathies is of great value to endocrine surgeons, ENT surgeons, endocrinologists, internal medicine and medical historians.

Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.

Introduction Anthony J. Edis, Richard H. Egdahl, Tracy K. Mcintosh, Contents Lester F. Williams xi 1 Surgery of the Parathyroids General Introduction 1 SURGICAL ANATOMY Primary Hyperparathyroidism 7 PATHOLOGY 7 DIAGNOSIS 11 PREOPERATIVE LOCALIZATION STUDIES 22 TREATMENT 27 Secondary Hyperparathyroidism 35 SIGNS, SYMPTOMS, COMPLICATIONS 35 CLINICAL MANAGEMENT 36 Tertiary Hyperparathyroidism 37 Operative Technique 38 CERVICAL EXPLORATION WITH REMOVAL OF A PARATHYROID ADENOMA 46 SUBTOTAL PARATHYROIDECTOMY FOR HYPERPLASIA 59 PARATHYROIDECTOMY FOR CARCINOMA 60 MEDIASTINAL EXPLORATION FOR PARATHYROID TUMOR 61 References 66 2 Surgery of the Thyroid 71 General Introduction 71 SURGICAL ANATOMY 72 Nodular Goiter and Thyroid Carcinoma 79 PATHOLOGY 79 DIAGNOSIS 82 TREATMENT OF THYROID NODULES 94 TREATMENT OF THYROID CANCER RELATED TO PATHOLOGIC TYPE 97 Hyperthyroidism 110 Graves' Disease 111 PATHOLOGY 111 DIAGNOSIS 112 TREATMENT 115 Plummer's Disease 120 PATHOLOGY 120 DIAGNOSIS 120 TREATMENT 122 Complications of Thyroid Surgery 123 PREVENTION AND MANAGEMENT 123 viii CONTENTS 127 Operative Techniques TOTAL THYROID LOBECTOMY 127 REMOVAL OF A SUBSTERNAL GOITER 134 SUBTOTAL THYROID LOBECTOMY 136 MODIFIED NECK DISSECTION FOR PAPILLARY THYROID CARCINOMA 141 References 144 3 Surgery of the Adrenals 151 151 General Introduction SURGICAL ANATOMY 152 Pheochromocytoma 155 PATHOLOGY 155 156 DIAGNOSIS PREOPERATIVE 162 TREATMENT 166 172 Primary Aldosteronism PATHOLOGY 172 DIAGNOSIS 174 178 PREOPERATIVE LOCALIZATION STUDIES TREATMENT 180 Cushing's Syndrome 181 CLASSIFICATION 182 DIAGNOSIS 187 PREOPERATIVE LOCALIZATION STUDIES 192 TREATMENT 194 Adrenal Gland and Metastatic Breast Carcinoma 198 Adrenocortical Carcinoma 200 DIAGNOSIS 201 PREOPERATIVE LOCALIZATION STUDIES AND STAGING 201 TREATMENT 202 PROGNOSIS 203 Nonfunctioning Adrenal Tumors 203

In this textbook, leading experts from highly acclaimed institutions describe evidence-based best practice in the management of a wide range of benign and malignant thyroid, parathyroid, adrenal, and neuroendocrine conditions. Detailed attention is devoted to the current role of surgery, including minimally invasive surgery and robotic surgery, in different endocrine disorders. The reader will also learn how best to respond to the problems that may be encountered during endocrine surgical practice. While much of the focus is on surgical aspects, the approach is multidisciplinary, with inclusion of information on recent advances in epidemiology, genetics, cytology, pathology, imaging modalities, and other treatment options. The clear text is complemented by instructive clinical cases as well as numerous high-quality illustrations and tables summarizing key points. This book will be of value for specialists in endocrine medicine and surgery as well as general surgeons with an interest in endocrine surgery.

This issue of Surgical Clinics of North America focuses on Surgical Management of Endocrine Disease and is edited by Drs. Rebecca S. Sippel and David F. Schneider. Articles will include: Evaluation of Thyroid Nodules; Decision Making in Indeterminate Thyroid Nodules and the Role of Molecular Testing; Extent of Thyroidectomy for Thyroid Cancer; Management of Nodal Disease in Thyroid Cancer; The Role of Surgery in Inflammatory Conditions of the Thyroid; Diagnosis and Evaluation of Primary Hyperparathyroidism; Who Benefits from Treatment of Primary Hyperparathyroidism?; Intra-operative Decision Making in Parathyroid Surgery; Surgical Management of MEN-1 and MEN-2; The Importance of Family History in the Management of Endocrine Disease; Evaluation of an Adrenal Incidentaloma; Evaluation and Management of Primary Hyperaldosteronism; When to Intervene for Subclinical Cushing’s Syndrome; Adrenocortical Cancer Treatment; Surgical Approaches to the Adrenal Gland; Evaluation and Management of Neuroendocrine Tumors of the Pancreas; and more!

In this issue of Surgical Clinics, guest editor Drs. Andrea Gillis and Jessica McMullin bring their considerable expertise to the topic of Endocrine Surgery. Top experts provide review articles on the current surgical management of the major endocrine glands, as well as articles on molecular markers, immunofluorescence, imaging, and health care disparities in endocrine surgical disorders. - Contains 16 relevant, practice-oriented topics including management of incidental thyroid nodules; the role of radiofrequency ablation in benign and malignant thyroid nodules; the role of molecular markers in thyroid cancer diagnostics and treatment; evaluation of adrenal incidentaloma; evaluation and surgical management of multiple endocrine neoplasias; and more. - Provides in-depth clinical reviews on endocrine surgery, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Editor Peter Mazzaglia and authors review the current management and procedures in endocrine surgery. Articles will cover: central compartment lymph node dissection for papillary thyroid cancer; evaluation of thyroid incidentaloma; the role of genetic markers in the evaluation and management of thyroid nodules; medical therapy for advanced forms of thyroid cancer; follicular lesions of the thyroid; controversy over radio-iodine ablation: who benefits?; minimizing cost while maximizing success in the pre-operative localization strategy for primary hyperparathyroidism; operative treatment for primary hyperparathyroidism; evaluation of adrenal incidentalomas: biochemical and radiographic characterization; hyperaldosteronism: diagnosis, lateralization, and treatment; subclinical Cushing’s syndrome; adrenocortical cancer update; and pancreatic neuroendocrine tumors.

Butterworths International Medical Review, Surgery 2: Endocrine Surgery is a 12-chapter text that describes various surgical procedures for the management of a specific endocrine problem. This book deals first with the principles of thyroidectomy and its application in thyrotoxicosis management. The subsequent chapter discusses the management of clinically solitary nodules without definite evidence of malignancy, such as lower cervical adenopathy or recurrent laryngeal nerve palsy. This topic is followed by considerations of reoperative parathyroid surgery; adrenalectomy for Cushing's syndrome management; percutaneous transhepatic portal and pancreatic vein catheterization for patients with organic hyperinsulinism, hypergastrinemia, and carcinoid syndrome; and pancreatic transplantation. This text further examines some surgical considerations of pancreatic islet cell and the pituitary in patients with multiple endocrine neoplasia type I. The concluding chapters explore the benefits and limitations of pre- and post-operative treatments of gastrinoma. These chapters also describe the principles and application of surgical treatments in primary aldosteronism and pheochromocytoma. This work will be of great value to established and in training endocrine surgeons, endocrinologists, and workers in other fields, including radiology and pathology.

This book describes the varying clinical manifestations of postural tachycardia syndrome (PoTS) and provides a robust yet practical set of clinical tools for those managing patients suffering with this syndrome. Guidance is provided by a range of disciplines relevant to PoTS including general and specialist assessments, associated conditions, diagnostic considerations, therapy and service models. Postural Tachycardia Syndrome: A Concise and Practical Guide to Management and Associated Conditions presents the scientific background and practical information for the busy medical professional, illustrating key features with care-based materials to help them manage this condition, which can be a challenge for patients and clinicians alike.

Textbook of Endocrine Surgery, Third Edition, is the latest edition of this highly illustrated, comprehensive guide. Edited by professors from the University of California, San Francisco, this authoritative textbook covers surgical procedures for a broad range of endocrine conditions. Comprised of four sections, divided into 81 chapters, this book examines disorders of the thyroid, parathyroid and adrenal glands, as well as neuroendocrine tumours of the pancreas and gastrointestinal tract. All chapters have been extensively revised and updated, and many new chapters have been added to this edition to reflect recent advances in the field. This book provides up to date information on aetiology, embryology, anatomy, clinical manifestations, diagnostic and localisation procedures, surgical and other treatment modalities for endocrine disorders. Enhanced by 550 full colour images and illustrations, Textbook of Endocrine Surgery is an invaluable resource for surgeons and endocrinologists. Key Points New edition of this richly illustrated, comprehensive guide to endocrine surgery Previous edition published 2005 (9780721601397) Editorial team from the University of California, San Francisco 550 full colour images and illustrations