Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels. - Features recent developments in theoretical and computational modeling for clinical researchers and engineers - Furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale - Includes chapters expertly authored by internationally recognized authorities in the fundamental and applied fields that are associated with microscale transport in living media

This text offers an introduction to the coarse-graining theory of macrotransport processes. Transport processes, whether macro or micro, refer to the continuum-level transport of mass, species, momentum, energy, electric charge and others, all of which processes are of great interest to scientists.

Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels.

Transport Phenomena: in Micro Process Engineeringputs fundamentals of chemical engineering into context with micro system technology, microfluidics, and transport processes within microstructures. After a general overview about both disciplines and common areas, the text presents numerous recent projects as examples. The text also applies transport of momentum, heat and mass in microstructures to chemical reactors, and coupled transport phenomena and their potential are illustrated to the reader. The book concludes with an evaluation of the state of the art and an outlook upon the next steps to come in research.

The homogenization of single phase gases or liquids with chemical reactive components by mixing belongs to one of the oldest basic operations applied in chemical engineering. The mixing process is used as an essential step in nearly all processes of the chemical industry as well as the pharmaceutical and food ind- tries. Recent experimentally and theoretically based results from research work lead to a fairly good prediction of the velocity fields in differend kinds of mixers, where as predictions of simultaneously proceeding homogeneous chemical re- tions, are still not reliable in a similar way. Therefore the design of equipment for mixing processes is still derived from measurements of the so called “mixing time” which is related to the applied methods of measurement and the special - sign of the test equipment itself. The cooperation of 17 research groups was stimulated by improved modern methods for experimental research and visualization, for simulations and nume- cal calculations of mixing and chemical reactions in micro and macro scale of time and local coordinates. The research work was financed for a six years period within the recently finished Priority Program of the German Research Foundation (DFG) named “Analysis, modeling and numerical prediction of flow-mixig with and without chemical reactions (SPP 1141)”. The objective of the investigations was to improve the prediction of efficiencies and selectivities of chemical re- tions on macroscopic scale.

Sulphatic claystones are among the most problematic rocks in tunnelling due to their distinctive swelling properties. They are known to have caused severe damage, for example, to numerous tunnels excavated in the Gypsum Keuper formation. The repairs were extremely costly and time-consuming, and often provided only a temporary solution. The setbacks experienced in tunnelling through Gypsum Keuper may be attributed, among other things, to our limited knowledge of the macroscopic principles governing the swelling process and the underlying microscopic mechanisms. The issues in question have formed the focal point of long-standing research in the Chair of Underground Construction at ETH Zurich. A series of theoretical and experimental research projects are being conducted to investigate the interactions between chemical reactions, transport processes and the observed macroscopic behaviour. The objective of the investigations is to improve our understanding of swelling processes in order to yield a scientifically established basis for design. This work has achieved important progress towards this objective. It has systematically and comprehensively analysed the thermodynamics and the kinetics of the chemical reactions involved in the swelling process, as well as their interplay with advective and diffusive ion transport. The topic is of great value in terms of further investigation in this area.

Understanding how fluids flow through though rocks is very important in a number of fields. Almost all of the world's oil and gas are produced from underground reservoirs. Knowledge of how they got where they are, what keeps them there and how they migrate through the rock is very important in the search for new resources, as well as for maximising the extraction of as much of the contained oil/gas as possible. Some contributors to this volume have been trying to understand real rocks in real situations and others have been working on computer models and laboratory simulations. Put together, these approaches have yielded very useful results, many of which are discussed in this volume.