The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup. In this book, my goal is to contribute to a growing body of literature on personalized medicine by tracing and analyzing how this field has blossomed in Asia. In so doing, I aim to illustrate how various social and economic forces shape the co-production of science and social order in global contexts. This book shows that there are inextricable transnational linkages between developing and developed countries and also provides a theoretically guided and empirically grounded understanding of the formation and usage of particular racial and ethnic human taxonomies in local, national and transnational settings. The Open Access version of this book, available at http://www.taylorfrancis.com/doi/view/10.4324/9781315537177 has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

"The book Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems represents a valuable interdisciplinary contribution created to fill an existing gap in the field of health economics and healthcare systems. The book brings the latest insights from the growing field of health economics and healthcare systems. It deals with various economic, technological, sociological, ethical, legal and philosophical implications and questions arising from the development and implementation of personalized medicine. It is unprecedented in combining practical guidelines for the use of economic tools and techniques with an analysis of the current process of decision-making in the health service sector. The book also provides several insights into the factors that determine human health, the socioeconomic aspects of population aging and the social implications of the evolving burden of disease. Some contributions are highly innovative and cover extremely relevant branches of medicine such as oncology, neurology and endocrinology. In addition, in a brave, yet professional and sovereign manner, the book covers the issue of biological predictors of health outcomes; though they are currently mainly used as global analytical methods, they are yet to be applied or have only recently been applied in clinical medicine. Further, it provides an example from traditional Korean medicine, a proven and valuable tool for personalized medical healthcare. This edition is unique in the sense that 30 chapters were written by 41 authors, all of them experts in their respective fields of research. The authors hail from Croatia, Hungary, South Korea and the United States. The volume is intended to serve as valuable teaching material for university students, as well as a reference book for research scholars, policymakers, business executives, health managers, physicians and freelance readers"--

Will genome-based precision medicine fix the problem of race/ethnicity-based medicine? To answer this question, Sun and Ong propose the concept of racialization of precision medicine, defined as the social processes by which racial/ethnic categories are incorporated (or not) into the development, interpretation, and implementation of precision medicine research and practice. Drawing on interview data with physicians and scientists in the field of cancer care, this book addresses the following questions: Who are the racializers in precision medicine, how and why do they do it? Under what conditions do clinicians personalize medical treatments in the context of cancer therapies? The chapters elucidate different ways in which racialization occurs and reveal that there exists an inherent contradiction in the usage of race/ethnicity as precision medicine moves from bench to bedside. The relative resources theory is proposed to explain that whether race/ethnicity-based medicine will be replaced by genomic medicine depends on the resources available at the individual and systemic levels. Furthermore, this book expands on how racialization happens not only in pharmacogenomic drug efficacy studies, but also in drug toxicity studies and cost-effectiveness studies. An important resource for clinicians, researchers, public health policymakers, health economists, and journalists on how to deracialize precision medicine.

Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

This set of multi-reference works is meant to be read together as the five volumes interlace one another like the laces of a shoe in the famous painting by Vincent van Gogh. Who will wear the shoes is a question long debated in art history and philosophy. If we take these five volumes from different points of view on the theory and practice of business storytelling then we have a crisscrossing, a new and impressive dialogue for the reader. This set is presented as a new way to lace up the laces of business storytelling.Volume 1 aims to recount narratives in a variety of ways so that the precepts of entrepreneurial storytelling can be made accessible to a variety of audiences — academic, practitioner, student, and community member. Entrepreneurship has a long history and tradition but there are disputed ways of doing business storytelling in entrepreneurship that the next four volumes articulate.Volume 2 provides insights into stories fostering the idea of business (and not necessarily business itself). It focuses specifically on history — contributing to the current debates within management and organizational history around the idea of 'the historic turn'. It reflects on the idea of business and beyond; could there be more to history and business storytelling than what has previously been accepted in the field? This book sets out to explore a diverse array of alternative modes and multiple ways of storying organizations. The editors intentionally sought to involve an international network of authors with diverse storytelling accounts of history as a way of helping build out this new storytelling paradigm in a diverse and inclusive ethic. As a result, this volume showcases a broad spectrum of critical storytelling from geographically diverse authors working in universities, small businesses, and public service throughout Brazil, Canada, Finland, the United Kingdom, and the United States. To reflect these dynamics, and for the stories in this volume to fit together, chapters were organized into three themes: stories of processing history, tales of history-as-method, and narratives of history through a business opportunity.Volume 3 features stories that reflect the exacerbated inequalities of race, gender, and income across the world. These inequalities and power relations remain continuously con-tested, particularly in these trying times, despite being captive to a particular economic ideology built on the premise of exploitation and subjugation. The stories told in this volume tell against the orthodoxy, the colonizer, and the (seemingly) powerful. They are organized as stories of resistance, emancipation, and transformation. They invite us to rethink the multiple ways to (re)structure power relations between the colonizer and the colonized, and open up spaces for the marginalized underprivileged voices.Volume 4 is designed to create a new business storytelling paradigm that critically approaches business narratives that have historically privileged a corporate agenda. It explores the various ways that images of the other in business are developed, presented, and accounted for through powerful and dominant narratives. The stories in this volume, collectively, help readers to understand, resist, and provide strategies for change through various analyses of how business narratives come to develop, get written, are legitimized, are challenged, and get changed over time.Volume 5 brings together the practices specific to the socioeconomic approach to management (SEAM). SEAM is a method of change management developed through research interventions carried out in more than 2,000 companies and organizations since 1975. This method is systemic, it considers the whole company, and tends to simultaneously increase social and economic performance by focusing mainly on the development of human skills and behaviors, making it possible to reduce dysfunctions and recycle hidden costs into added value.

Medicinal flora plays an important role in health care systems across the world. Out of the half million flowering plants, around 50.000 species are valued for their therapeutic properties. During the last few decades, 20% of the world’s population used plants and/or their derived products as a source of medicine. WHO stated that 80% population around the globe, specifically the rural communities, depend on medicinal plants for their basic healthcare needs. To this end, plant-based phytochemicals are known to have hepato-protective, anti-carcinogenic, anti-allergic, anti-inflammatory, antimicrobial, antioxidant actions. This book is a guide to ~280 plant species of medicinal flora that demonstrates global relevance. Our goal is to share local knowledge about phytomedicines to a worldwide audience. It is an illustrated reference that documents and preserves the existing knowledge on these plant taxa, with a social and cultural (ethnobotanical) emphasis. This book also provides comprehensive and useful information about traditional uses of medicinal plants by the local communities for the treatment of various prevalent diseases. It contains comprehensive descriptions of each species including family, synonyms, English name, distribution, altitude, habitat, morphological description, life form, part used, mode of utilization, diseases category, recipes, other medicinal uses, phytochemical activity and toxicity.

Digital humanities is a dynamic and emerging field that aspires to enhance traditional research and scholarship through digital media. Although countries around the world are witnessing the widespread adoption of digital humanities, only a small portion of the literature discusses its development in the Asia Pacific region. Digital Humanities and Scholarly Research Trends in the Asia-Pacific provides innovative insights into the development of digital humanities and their ability to facilitate academic exchange and preserve cultural heritage. The content covers challenges including the need to maintain digital humanities momentum in libraries and research communities, to increase international collaboration, to maintain and promote developed digital projects, to deploy and redeploy resources to support research, and to build new skillsets and new professionals in the library. It is designed for librarians, government agencies, industry professionals, academicians, and researchers.

Public Health, Personal Health and Pills explores the processes and effects of the increasing governance of our lives through pharmaceuticals, looking at the moral, interactional, social and political forces that shape our use of them. It demonstrates the ways in which social relationships and identities are developed, sustained and transformed through medication use. Building on the extensive medicalisation of health literature, and the more recent concept of pharmaceuticalisation, this pioneering book is firmly based on empirical research and sociological theory. It brings together macro considerations of trends in pharmaceutical consumption, regulation and policy, micro considerations of the decision-making and the negotiation of medication use in homes and clinics, and an institutional analysis of the role of drug monitoring agencies, drug subsidising agencies, drug trial methodologies and the media. This book is a contribution to a burgeoning sociological interest in medication use, and will be of interest to a multidisciplinary audience of scholars and students of sociology, science and technology studies, pharmacy and health studies.