This book covers mathematical foundations and methods for the computerized analysis of shapes, providing the requisite background in geometry and functional analysis and introducing various algorithms and approaches to shape modeling, with a special focus on the interesting connections between shapes and their transformations by diffeomorphisms. A direct application is to computational anatomy, for which techniques such as large‒deformation diffeomorphic metric mapping and metamorphosis, among others, are presented. The appendices detail a series of classical topics (Hilbert spaces, differential equations, Riemannian manifolds, optimal control). The intended audience is applied mathematicians and mathematically inclined engineers interested in the topic of shape analysis and its possible applications in computer vision or medical imaging. The first part can be used for an advanced undergraduate course on differential geometry with a focus on applications while the later chapters are suitable for a graduate course on shape analysis through the action of diffeomorphisms. Several significant additions appear in the 2nd edition, most notably a new chapter on shape datasets, and a discussion of optimal control theory in an infinite-dimensional framework, which is then used to enrich the presentation of diffeomorphic matching.

Shapes are complex objects to apprehend, as mathematical entities, in terms that also are suitable for computerized analysis and interpretation. This volume provides the background that is required for this purpose, including different approaches that can be used to model shapes, and algorithms that are available to analyze them. It explores, in particular, the interesting connections between shapes and the objects that naturally act on them, diffeomorphisms. The book is, as far as possible, self-contained, with an appendix that describes a series of classical topics in mathematics (Hilbert spaces, differential equations, Riemannian manifolds) and sections that represent the state of the art in the analysis of shapes and their deformations. A direct application of what is presented in the book is a branch of the computerized analysis of medical images, called computational anatomy.

Understanding how a single shape can incur a complex range of transformations, while defining the same perceptually obvious figure, entails a rich and challenging collection of problems, at the interface between applied mathematics, statistics and computer science. The program on Mathematics of Shapes and Applications, was held at the Institute for Mathematical Sciences at the National University of Singapore in 2016. It provided discussions on theoretical developments and numerous applications in computer vision, object recognition and medical imaging.The analysis of shapes is an example of a mathematical problem directly connected with applications while offering deep open challenges to theoretical mathematicians. It has grown, over the past decades, into an interdisciplinary area in which researchers studying infinite-dimensional Riemannian manifolds (global analysis) interact with applied mathematicians, statisticians, computer scientists and biomedical engineers on a variety of problems involving shapes.The volume illustrates this wealth of subjects by providing new contributions on the metric structure of diffeomorphism groups and shape spaces, recent developments on deterministic and stochastic models of shape evolution, new computational methods manipulating shapes, and new statistical tools to analyze shape datasets. In addition to these contributions, applications of shape analysis to medical imaging and computational anatomy are discussed, leading, in particular, to improved understanding of the impact of cognitive diseases on the geometry of the brain.

Presents the latest groundbreaking theoretical foundation to shape optimization in a form accessible to mathematicians, scientists and engineers.

This considerably enriched new edition provides a self-contained presentation of the mathematical foundations, constructions, and tools necessary for studying problems where the modeling, optimization, or control variable is the shape or the structure of a geometric object.

This text discusses Lie groups of transformations and basic symmetry methods for solving ordinary and partial differential equations. It places emphasis on explicit computational algorithms to discover symmetries admitted by differential equations and to construct solutions resulting from symmetries. This new edition covers contact transformations, Lie-B cklund transformations, and adjoints and integrating factors for ODEs of arbitrary order.

The tools to use for problems where the modeling, optimization, or control variable is the structure of a geometric object.

This book provides an authoritative introduction to the rapidly growing field of chemical reaction network theory. In particular, the book presents deep and surprising theorems that relate the graphical and algebraic structure of a reaction network to qualitative properties of the intricate system of nonlinear differential equations that the network induces. Over the course of three main parts, Feinberg provides a gradual transition from a tutorial on the basics of reaction network theory, to a survey of some of its principal theorems, and, finally, to a discussion of the theory’s more technical aspects. Written with great clarity, this book will be of value to mathematicians and to mathematically-inclined biologists, chemists, physicists, and engineers who want to contribute to chemical reaction network theory or make use of its powerful results.

Over the past 15 years, there has been a growing need in the medical image computing community for principled methods to process nonlinear geometric data. Riemannian geometry has emerged as one of the most powerful mathematical and computational frameworks for analyzing such data. Riemannian Geometric Statistics in Medical Image Analysis is a complete reference on statistics on Riemannian manifolds and more general nonlinear spaces with applications in medical image analysis. It provides an introduction to the core methodology followed by a presentation of state-of-the-art methods. Beyond medical image computing, the methods described in this book may also apply to other domains such as signal processing, computer vision, geometric deep learning, and other domains where statistics on geometric features appear. As such, the presented core methodology takes its place in the field of geometric statistics, the statistical analysis of data being elements of nonlinear geometric spaces. The foundational material and the advanced techniques presented in the later parts of the book can be useful in domains outside medical imaging and present important applications of geometric statistics methodology Content includes: - The foundations of Riemannian geometric methods for statistics on manifolds with emphasis on concepts rather than on proofs - Applications of statistics on manifolds and shape spaces in medical image computing - Diffeomorphic deformations and their applications As the methods described apply to domains such as signal processing (radar signal processing and brain computer interaction), computer vision (object and face recognition), and other domains where statistics of geometric features appear, this book is suitable for researchers and graduate students in medical imaging, engineering and computer science. - A complete reference covering both the foundations and state-of-the-art methods - Edited and authored by leading researchers in the field - Contains theory, examples, applications, and algorithms - Gives an overview of current research challenges and future applications

The three-volume set LNCS 8673, 8674, and 8675 constitutes the refereed proceedings of the 17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014, held in Boston, MA, USA, in September 2014. Based on rigorous peer reviews, the program committee carefully selected 253 revised papers from 862 submissions for presentation in three volumes. The 53 papers included in the third volume have been organized in the following topical sections: shape and population analysis; brain; diffusion MRI; and machine learning.